Search Results - "Ueda, H. R"

Seeing the forest and trees: whole-body and whole-brain imaging for circadian biology by Ode, K. L., Ueda, H. R.

“…Recent advances in methods for making mammalian organs translucent have made possible whole‐body fluorescent imaging with single‐cell resolution. Because…”
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Fluorescence tissue microscopy by Sacconi, L., Ueda, H.R., Pagès, S., Silvestri, L.

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Systems biology of mammalian circadian clocks by Ueda, H R

“…Systems Biology is a natural extension of molecular biology and can be defined as biology after identification of key gene(s). Systems-biological research is…”
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A transcription factor response element for gene expression during circadian night by Ueda, Hiroki R, Shigeyoshi, Yasufumi, Chen, Wenbin, Adachi, Akihito, Wakamatsu, Hisanori, Hayashi, Satoko, Takasugi, Tomohiro, Nagano, Mamoru, Nakahama, Ken-ichi, Suzuki, Yutaka, Sugano, Sumio, Iino, Masamitsu, Hashimoto, Seiichi

“…Mammalian circadian clocks consist of complex integrated feedback loops that cannot be elucidated without comprehensive measurement of system dynamics and…”
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Genome-wide transcriptional orchestration of circadian rhythms in Drosophila by Ueda, Hiroki R, Matsumoto, Akira, Kawamura, Miho, Iino, Masamitsu, Tanimura, Teiichi, Hashimoto, Seiichi

“…Circadian rhythms govern the behavior, physiology, and metabolism of living organisms. Recent studies have revealed the role of several genes in the clock…”
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Universality and Flexibility in Gene Expression from Bacteria to Human by Ueda, Hiroki R, Hayashi, Satoko, Matsuyama, Shinichi, Yomo, Tetsuya, Hashimoto, Seiichi, Kay, Steve A, Hogenesch, John B, Iino, Masamitsu

“…Highly parallel experimental biology is offering opportunities to not just accomplish work more easily, but to explore for underlying governing principles…”
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Robust Oscillations within the Interlocked Feedback Model of Drosophila Circadian Rhythm by UEDA, HIROKI R., HAGIWARA, MASATOSHI, KITANO, HIROAKI

“…A mechanism for generating circadian rhythms has been of major interest in recent years. After the discovery of per and tim, a model with a simple feedback…”
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The period gene and allochronic reproductive isolation in Bactrocera cucurbitae by Miyatake, Takahisa, Matsumoto, Akira, Matsuyama, Takashi, Ueda, Hiroki R., Toyosato, Tetsuya, Tanimura, Teiichi

“…Clock genes that pleiotropically control circadian rhythm and the time of mating may cause allochronic reproductive isolation in the melon fly…”
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Intercellular Coupling Mechanism for Synchronized and Noise-Resistant Circadian Oscillators by UEDA, HIROKI R., HIROSE, KENZO, IINO, MASAMITSU

“…The circadian clock in multicellular organisms consists of multiple autonomous single-cell oscillators. These individual oscillator cells produce coherent…”
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System-level identification of transcriptional circuits underlying mammalian circadian clocks by Ueda, Hiroki R, Hayashi, Satoko, Chen, Wenbin, Sano, Motoaki, Machida, Masayuki, Shigeyoshi, Yasufumi, Iino, Masamitsu, Hashimoto, Seiichi

“…Mammalian circadian clocks consist of complexly integrated regulatory loops, making it difficult to elucidate them without both the accurate measurement of…”
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An improved single-cell cDNA amplification method for efficient high-density oligonucleotide microarray analysis by Kurimoto, Kazuki, Yabuta, Yukihiro, Ohinata, Yasuhide, Ono, Yukiko, Uno, Kenichiro D., Yamada, Rikuhiro G., Ueda, Hiroki R., Saitou, Mitinori

“…A systems-level understanding of a small but essential population of cells in development or adulthood (e.g. somatic stem cells) requires accurate quantitative…”
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Feedback repression is required for mammalian circadian clock function by Ueda, Hiroki R, Hogenesch, John B, Sato, Trey K, Yamada, Rikuhiro G, Ukai, Hideki, Baggs, Julie E, Miraglia, Loren J, Kobayashi, Tetsuya J, Welsh, David K, Kay, Steve A

“…Direct evidence for the requirement of transcriptional feedback repression in circadian clock function has been elusive. Here, we developed a molecular genetic…”
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Molecular-Timetable Methods for Detection of Body Time and Rhythm Disorders from Single-Time-Point Genome-Wide Expression Profiles by Ueda, Hiroki R., Chen, Wenbin, Minami, Yoichi, Honma, Sato, Honma, Kenichi, Iino, Masamitsu, Hashimoto, Seiichi, Waterman, Michael S.

“…Detection of individual body time (BT) via a single-time-point assay has been a longstanding unfulfilled dream in medicine, because BT information can be…”
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