Seroprevalence Rates of Hepatitis C Virus (Hcv) Antibody And Hepatitis B Virus Surface Antigen (Hbsag) in Blood Donors in A Southwestern Nigerian City

Seroprevalence Rates of Hepatitis C Virus (Hcv) Antibody And Hepatitis B Virus Surface Antigen (Hbsag) in Blood Donors in A Southwestern Nigerian City

Hepatitis B and C have been identified as major causes of Transfusion transmitted infections, in Nigeria. Our objective was to determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) in prospective blood donors in Abeokuta, Nigeria. 305 blood donors were screened for the pres...

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Bibliographic Details
Published in:Journal of immunoassay & immunochemistry Vol. 36; no. 1; pp. 91 - 99
Main Authors: Motayo, Babatunde O., Akpa, Onoja M., Ezeani, Isreal, Faneye, Adedayo O., Udo, Usen A., Onoja, Bernard
Format: Journal Article
Language:English
Published: England Taylor & Francis 02-01-2015
Subjects:
abeokuta
blood donors
Cross-Sectional Studies
Female
HBsAg
HCV
Hepatitis B Surface Antigens - blood
Hepatitis B Surface Antigens - immunology
Hepatitis C Antibodies - blood
Hepatitis C Antibodies - immunology
Humans
Male
Nigeria - epidemiology
Prospective Studies
seoprevailence
Seroepidemiologic Studies
Nigeria
blood donors
HBsAg
HCV
abeokuta
seoprevailence
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Summary:Hepatitis B and C have been identified as major causes of Transfusion transmitted infections, in Nigeria. Our objective was to determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) in prospective blood donors in Abeokuta, Nigeria. 305 blood donors were screened for the presence of Hepatitis B virus surface antigen (HBsAg) and HCV using a rapid immunochromatographic kit (DiaSpot®). Demographic information was also collected. Males constituted 96.4%, singles were the majority with 65%. Prevalence of HBsAg was 9.8%, HCV 1.3%, and dual positivity 0.3%. Prevalence of HBsAg and HCV among males was 10.2% and 1.4%, while females recorded 0.0% for HCV and HBsAg. Dual positivity was recorded in a male (0.33%). Analysis of the study variables revealed that only educational status was statistically associated with positivity of HBsAg , HCV prevalence was highest in the illiterate group it was not statistically significant (P > 0.05). We report the prevalence rates of anti-HCV Ab and HBsAg in blood donors from Ogun State, Nigeria. Our results reveals higher rate of HBsAg and evidence of co-infection with both viruses, illiteracy was the only variable associated with HBV infection. We advocate for the inclusion of anti-HBc or HBeAg in donor screening in our environment.
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ISSN:1532-1819
1532-4230
DOI:10.1080/15321819.2014.899256