Search Results - "Udina, E."
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Voluntary wheel running preserves lumbar perineuronal nets, enhances motor functions and prevents hyperreflexia after spinal cord injury
Published in Experimental neurology (01-02-2021)“…Perineuronal nets (PNN) are a promising candidate to harness neural plasticity since their activity-dependent modulation allows to either stabilize the…”
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Aberrant perineuronal nets alter spinal circuits, impair motor function, and increase plasticity
Published in Experimental neurology (01-12-2022)“…Perineuronal nets (PNNs) are a specialized extracellular matrix that have been extensively studied in the brain. Cortical PNNs are implicated in synaptic…”
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Effective decellularization of human nerve matrix for regenerative medicine with a novel protocol
Published in Cell and tissue research (01-04-2021)“…Injuries to the peripheral nerves represent a frequent cause of permanent disability in adults. The repair of large nerve lesions involves the use of…”
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Tubulization with chitosan guides for the repair of long gap peripheral nerve injury in the rat
Published in Microsurgery (01-05-2015)“…Biosynthetic guides can be an alternative to nerve grafts for reconstructing severely injured peripheral nerves. The aim of this study was to evaluate the…”
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Rolipram-induced elevation of cAMP or chondroitinase ABC breakdown of inhibitory proteoglycans in the extracellular matrix promotes peripheral nerve regeneration
Published in Experimental neurology (01-05-2010)“…The inhibitory growth environment of myelin and extracellular matrix proteoglycans in the central nervous system may be overcome by elevating neuronal cAMP or…”
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Schwann cell targeting via intrasciatic injection of AAV8 as gene therapy strategy for peripheral nerve regeneration
Published in Gene therapy (01-06-2011)“…Efficient transduction of the peripheral nervous system (PNS) is required for gene therapy of acquired and inherited neuropathies, neuromuscular diseases and…”
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Activation of 5-HT2A Receptors Restores KCC2 Function and Reduces Neuropathic Pain after Spinal Cord Injury
Published in Neuroscience (01-09-2018)“…•TCB-2 reduces mechanical allodynia and thermal hyperalgesia after a spinal cord hemisection.•This effect is lost when intrathecal DIOA, a blocker of KCC2, is…”
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Biocompatibility of Chronically Implanted Transverse Intrafascicular Multichannel Electrode (TIME) in the Rat Sciatic Nerve
Published in IEEE transactions on biomedical engineering (01-08-2011)“…The transverse intrafascicular multichannel electrode (TIME) is intended to be transversally implanted in the peripheral nerve and to selectively interface…”
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Implementation of a program to reduce allogeneic blood transfusión in total hip arthroplasty: 6AP2-7
Published in European journal of anaesthesiology (01-06-2013)Get full text
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Neurobiological Assessment of Regenerative Electrodes for Bidirectional Interfacing Injured Peripheral Nerves
Published in IEEE transactions on biomedical engineering (01-06-2007)“…Regenerative electrodes are designed to interface regenerated axons from a sectioned peripheral nerve. Applicability of regenerative electrodes depends on…”
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Brief electrical stimulation accelerates axon regeneration in the peripheral nervous system and promotes sensory axon regeneration in the central nervous system
Published in Motor control (01-10-2009)“…Injured peripheral but not central nerves regenerate their axons but functional recovery is often poor. We demonstrate that prolonged periods of axon…”
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FK506 enhances reinnervation by regeneration and by collateral sprouting of peripheral nerve fibers
Published in Experimental neurology (01-09-2003)“…We examined the effects of FK506 administration on the degree of target reinnervation by regenerating axons (following sciatic nerve crush) and by collateral…”
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Comparison of continuous and discontinuous FK506 administration on autograft or allograft repair of sciatic nerve resection
Published in Muscle & nerve (01-06-2004)“…An immunosuppressant drug that also possesses neuroregenerative properties, FK506 enhances the rate of axonal regeneration and improves recovery after nerve…”
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Bimodal dose-dependence of FK506 on the rate of axonal regeneration in mouse peripheral nerve
Published in Muscle & nerve (01-09-2002)“…FK506 has been shown to enhance the rate of axonal regeneration after peripheral nerve lesions. However, quite variable doses of FK506 have been used in…”
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FK506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat
Published in Journal of neuroscience research (15-09-2005)“…We examined the efficacy of FK506 in reducing tissue damage after spinal cord injury in comparison to methylprednisolone (MP) treatment. Rats were subjected to…”
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FK506 enhances regeneration of axons across long peripheral nerve gaps repaired with collagen guides seeded with allogeneic Schwann cells
Published in Glia (01-08-2004)“…We assessed the effects of FK506 administration on regeneration after a 6‐mm gap repair with a collagen guide seeded with allogeneic Schwann cells (SCs) in the…”
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Effects of the immunophilin ligand FK506 on nerve regeneration in collagen guides seeded with Schwann cells in rats
Published in Neuroscience letters (04-03-2004)“…We assessed the effects of FK506 administration on regeneration after 5-mm gap repair with a collagen guide seeded with syngeneic Schwann cells in the rat…”
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Effects of FK506 on nerve regeneration and reinnervation after graft or tube repair of long nerve gaps
Published in Muscle & nerve (01-07-2001)“…We compared the effects of FK506 administration on regeneration and reinnervation after sciatic nerve resection and repair with an autologous graft or with a…”
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