Search Results - "Uddback, Ida"
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Group A streptococci are protected from amoxicillin-mediated killing by vesicles containing β-lactamase derived from Haemophilus influenzae
Published in Journal of antimicrobial chemotherapy (01-01-2014)“…Group A streptococci (GAS) cause, among other infections, pharyngotonsillitis in children. The species is frequently localized with the Gram-negative…”
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Combined local and systemic immunization is essential for durable T-cell mediated heterosubtypic immunity against influenza A virus
Published in Scientific reports (01-02-2016)“…The threat from unpredictable influenza virus pandemics necessitates the development of a new type of influenza vaccine. Since the internal proteins are highly…”
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A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice
Published in Vaccines (Basel) (15-07-2020)“…Due to constant antigenic drift and shift, current influenza-A vaccines need to be redesigned and administered annually. A universal flu vaccine (UFV) that…”
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Vaccine induced memory CD8 + T cells efficiently prevent viral transmission from the respiratory tract
Published in Frontiers in immunology (18-12-2023)“…Mucosal immunization eliciting local T-cell memory has been suggested for improved protection against respiratory infections caused by viral variants evading…”
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Pulmonary monocytes interact with effector T cells in the lung tissue to drive T RM differentiation following viral infection
Published in Mucosal immunology (01-01-2020)“…Lung resident memory CD8 T cells (T ) are critical for protection against respiratory viruses, but the cellular interactions required for their development are…”
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Harnessing Cross-Reactive CD8 + T RM Cells for Long-Standing Protection Against Influenza A Virus
Published in Viral immunology (01-04-2020)Get more information
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Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors
Published in Scientific reports (08-12-2016)“…Intracellular pathogens represent a serious threat during early life. Importantly, even though the immune system of newborns may be characterized as…”
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Long-term maintenance of lung resident memory T cells is mediated by persistent antigen
Published in Mucosal immunology (01-01-2021)“…Tissue-resident memory T cells (T RM ) in the lungs are pivotal for protection against repeated infection with respiratory viruses. However, the gradual loss…”
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PB1 as a potential target for increasing the breadth of T-cell mediated immunity to Influenza A
Published in Scientific reports (07-10-2016)“…Recently, we showed that combined intranasal and subcutaneous immunization with a non-replicating adenoviral vector expressing NP of influenza A, strain PR8,…”
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Persistent Antigen Harbored by Alveolar Macrophages Enhances the Maintenance of Lung-Resident Memory CD8 + T Cells
Published in The Journal of immunology (1950) (01-11-2022)“…Lung tissue-resident memory T cells are crucial mediators of cellular immunity against respiratory viruses; however, their gradual decline hinders the…”
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Prevention of respiratory virus transmission by resident memory CD8+ T cells
Published in Nature (London) (08-02-2024)“…An ideal vaccine both attenuates virus growth and disease in infected individuals and reduces the spread of infections in the population, thereby generating…”
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Pulmonary monocytes interact with effector T cells in the lung tissue to drive TRM differentiation following viral infection
Published in Mucosal immunology (2020)“…Lung resident memory CD8 T cells (T RM ) are critical for protection against respiratory viruses, but the cellular interactions required for their development…”
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A Novel H-2d Epitope for Influenza A Polymerase Acidic Protein
Published in Viruses (14-03-2022)“…Understanding the complexity of the T-cell epitope hierarchy in humans through mouse models can be difficult. In particular, using only one murine strain, the…”
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837 Combination treatment with ATOR-4066, a Neo-X-Prime™ bispecific antibody targeting CD40 and CEACAM5, and anti-PD-1 reverses T cell exhaustion in vitro
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundATOR-4066 is a preclinical stage bispecific antibody targeting CD40 and CEACAM5, developed from Alligator’s novel Neo-X-Prime™ antibody technology…”
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Lung-resident memory CD8+ T cells prevent transmission of respiratory viruses
Published in The Journal of immunology (1950) (01-05-2020)“…Lung tissue-resident memory CD8+ T cells (TRM) reduce viral replication and limit pathology following respiratory virus infections. In particular, TRM are…”
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Identifying mechanisms that enhance the longevity of tissue-resident memory T cells in the lung
Published in The Journal of immunology (1950) (01-05-2020)“…Lung tissue-resident memory T cells (TRM) are crucial mediators of cellular immunity against influenza viruses, but the number of these cells in the lung…”
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Resident Memory CD8+ T cells in the respiratory tract prevent transmission of respiratory viruses
Published in The Journal of immunology (1950) (01-05-2021)“…Tissue-resident memory CD8+ T cells (TRM) in the respiratory tract reduce viral replication and limit pathology following respiratory virus infections. In…”
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Identifying mechanisms that enhance the longevity of tissue-resident memory CD8+ T cells in the lung
Published in The Journal of immunology (1950) (01-05-2021)“…Lung tissue-resident memory CD8+ T cells (TRM) are crucial mediators of cellular immunity against influenza viruses, but the number of these cells in the lung…”
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Persistent antigen can maintain lung resident memory CD8 T cells long-term
Published in The Journal of immunology (1950) (01-05-2019)“…A sub-population of memory T cells, tissue resident memory T cells (TRM), have in recent years gained attention for their indispensable role in heterologous…”
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PB1 as a potential target for increasing the breadth of T-cell mediated immunity to Influenza A
Published in The Journal of immunology (1950) (01-05-2017)“…Current influenza vaccines are inducing antibody-mediated immunity toward the surface proteins hemagglutinin and neuraminidase. High variability of these…”
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