Search Results - "Udatha, D. B. R. K. Gupta"

Linking genotype and phenotype of Saccharomyces cerevisiae strains reveals metabolic engineering targets and leads to triterpene hyper-producers by Madsen, Karina M, Udatha, Gupta D B R K, Semba, Saori, Otero, Jose M, Koetter, Peter, Nielsen, Jens, Ebizuka, Yutaka, Kushiro, Tetsuo, Panagiotou, Gianni

“…Metabolic engineering is an attractive approach in order to improve the microbial production of drugs. Triterpenes is a chemically diverse class of compounds…”
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Common and distant structural characteristics of feruloyl esterase families from Aspergillus oryzae by Udatha, D B R K Gupta, Mapelli, Valeria, Panagiotou, Gianni, Olsson, Lisbeth

“…Feruloyl esterases (FAEs) are important biomass degrading accessory enzymes due to their capability of cleaving the ester links between hemicellulose and…”
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The interplay of descriptor-based computational analysis with pharmacophore modeling builds the basis for a novel classification scheme for feruloyl esterases by Udatha, D.B.R.K. Gupta, Kouskoumvekaki, Irene, Olsson, Lisbeth, Panagiotou, Gianni

“…One of the most intriguing groups of enzymes, the feruloyl esterases (FAEs), is ubiquitous in both simple and complex organisms. FAEs have gained importance in…”
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Secretion of the Intimin Passenger Domain Is Driven by Protein Folding by Leo, Jack C., Oberhettinger, Philipp, Yoshimoto, Shogo, Udatha, D. B. R. K. Gupta, Morth, J. Preben, Schütz, Monika, Hori, Katsutoshi, Linke, Dirk

“…Intimin is an essential adhesin of attaching and effacing organisms such as entropathogenic Escherichia coli. It is also the prototype of type Ve secretion or…”
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Yeast biological networks unfold the interplay of antioxidants, genome and phenotype, and reveal a novel regulator of the oxidative stress response by Otero, Jose M, Papadakis, Manos A, Udatha, D B R K Gupta, Nielsen, Jens, Panagiotou, Gianni

“…Identifying causative biological networks associated with relevant phenotypes is essential in the field of systems biology. We used ferulic acid (FA) as a…”
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Introducing a New Article Type “Innovation Reports”: Venue for Communication & Dissemination of Collaborative Projects by Udatha, D.B.R.K. Gupta

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Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis by Chung, Brian K, Guevel, Bardia T, Reynolds, Gary M, Gupta Udatha, D.B.R.K, Henriksen, Eva Kristine Klemsdal, Stamataki, Zania, Hirschfield, Gideon M, Karlsen, Tom Hemming, Liaskou, Evaggelia

“…Abstract Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are immune-mediated biliary diseases that demonstrate prominent and…”
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Type V Secretion Systems in Bacteria by Fan, Enguo, Chauhan, Nandini, Udatha, D B R K Gupta, Leo, Jack C, Linke, Dirk

“…Type V secretion denotes a variety of secretion systems that cross the outer membrane in Gram-negative bacteria but that depend on the Sec machinery for…”
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How well do the substrates KISS the enzyme? Molecular docking program selection for feruloyl esterases by Udatha, D. B. R. K. Gupta, Sugaya, Nobuyoshi, Olsson, Lisbeth, Panagiotou, Gianni

“…Molecular docking is the most commonly used technique in the modern drug discovery process where computational approaches involving docking algorithms are used…”
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Multiple nucleophilic elbows leading to multiple active sites in a single module esterase from Sorangium cellulosum by Udatha, D.B.R.K. Gupta, Madsen, Karina Marie, Panagiotou, Gianni, Olsson, Lisbeth

“…The catalytic residues in carbohydrate esterase enzyme families constitute a highly conserved triad: serine, histidine and aspartic acid. This catalytic triad…”
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Understanding the pH-dependent immobilization efficacy of feruloyl esterase-C on mesoporous silica and its structure–activity changes by Thörn, Christian, Udatha, D.B.R.K. Gupta, Zhou, Hao, Christakopoulos, Paul, Topakas, Evangelos, Olsson, Lisbeth

“…•Surface charge distribution affects enzyme orientation and substrate accessibility.•Immobilization pH alters the specific activity irrespective of reaction…”
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Deciphering the signaling mechanisms of the plant cell wall degradation machinery in Aspergillus oryzae by Udatha, D B R K Gupta, Topakas, Evangelos, Salazar, Margarita, Olsson, Lisbeth, Andersen, Mikael R, Panagiotou, Gianni

“…The gene expression and secretion of fungal lignocellulolytic enzymes are tightly controlled at the transcription level using independent mechanisms to respond…”
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Targeted metabolic engineering guided by computational analysis of single-nucleotide polymorphisms (SNPs) by Udatha, D B R K Gupta, Rasmussen, Simon, Sicheritz-Pontén, Thomas, Panagiotou, Gianni

“…The non-synonymous SNPs, the so-called non-silent SNPs, which are single-nucleotide variations in the coding regions that give "birth" to amino acid mutations,…”
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Towards Classification and Functional Description of Enzymes: A Case Study of Feruloyl Esterases by Udatha, D. B. R. K Gupta

“…The prediction of enzyme functionality from sequence or structure data remains a challenging task that can be best addressed by studying the structure-function…”
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