Search Results - "Uchii, Kie"

Structural Basis for Anti-non-alcoholic Fatty Liver Disease and Diabetic Dyslipidemia Drug Saroglitazar as a PPAR α/γ Dual Agonist by Honda, Akihiro, Kamata, Shotaro, Satta, Chihiro, Machida, Yui, Uchii, Kie, Terasawa, Kazuki, Nemoto, Ayane, Oyama, Takuji, Ishii, Isao

“…Peroxisome proliferator-activated receptors (PPARs) are nuclear receptor-type transcription factors that consist of three subtypes (α, γ, and β/δ) with…”
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Functional and Structural Insights into Human PPARα/δ/γ Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate by Honda, Akihiro, Kamata, Shotaro, Akahane, Makoto, Machida, Yui, Uchii, Kie, Shiiyama, Yui, Habu, Yuki, Miyawaki, Saeka, Kaneko, Chihiro, Oyama, Takuji, Ishii, Isao

“…Among the agonists against three peroxisome proliferator-activated receptor (PPAR) subtypes, those against PPARα (fibrates) and PPARγ (glitazones) are…”
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Functional and Structural Insights into the Human PPARα/δ/γ Targeting Preferences of Anti-NASH Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor by Kamata, Shotaro, Honda, Akihiro, Ishikawa, Ryo, Akahane, Makoto, Fujita, Ayane, Kaneko, Chihiro, Miyawaki, Saeka, Habu, Yuki, Shiiyama, Yui, Uchii, Kie, Machida, Yui, Oyama, Takuji, Ishii, Isao

“…No therapeutic drugs are currently available for nonalcoholic steatohepatitis (NASH) that progresses from nonalcoholic fatty liver via oxidative…”
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