Search Results - "Uchida, Derek A"

Heterogeneous Pulmonary Phenotypes Associated With Mutations in the Thyroid Transcription Factor Gene NKX2-1 by Hamvas, Aaron, MD, Deterding, Robin R., MD, Wert, Susan E., PhD, White, Frances V., MD, Dishop, Megan K., MD, Alfano, Danielle N., MD, Halbower, Ann C., MD, Planer, Benjamin, MD, Stephan, Mark J., MD, Uchida, Derek A., MD, Williames, Lee D., MD, Rosenfeld, Jill A., MS, Lebel, Robert Roger, MD, Young, Lisa R., MD, Cole, F. Sessions, MD, Nogee, Lawrence M., MD

“…Background Mutations in the gene encoding thyroid transcription factor, NKX2-1 , result in neurologic abnormalities, hypothyroidism, and neonatal respiratory…”
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Fluticasone Propionate Pharmacogenetics: CYP3A422 Polymorphism and Pediatric Asthma Control by Stockmann, Chris, MSc, Fassl, Bernhard, MD, Gaedigk, Roger, PhD, Nkoy, Flory, MD, MPH, MS, Uchida, Derek A., MD, Monson, Steven, BS, Reilly, Christopher A., PhD, Leeder, J. Steven, PharmD, PhD, Yost, Garold S., PhD, Ward, Robert M., MD

“…Objective To determine the relationship between allelic variations in genes involved in fluticasone propionate (FP) metabolism and asthma control among…”
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Effect of CYP3A53 on asthma control among children treated with inhaled beclomethasone by Stockmann, Chris, MSc, Reilly, Christopher A., PhD, Fassl, Bernhard, MD, Gaedigk, Roger, PhD, Nkoy, Flory, MD, MPH, MS, Stone, Bryan, MD, Roberts, Jessica K., PhD, Uchida, Derek A., MD, Leeder, J. Steven, PharmD, PhD, Sherwin, Catherine M.T., PhD, Spigarelli, Michael G., MD, PhD, Yost, Garold S., PhD, Ward, Robert M., MD

“…[...]the relative contributions of these SNPs to the clinical effects we observed could not be differentiated, although it is well known that CYP3A5*3 causes…”
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Improving Pediatric Asthma Care and Outcomes Across Multiple Hospitals by Nkoy, Flory, Fassl, Bernhard, Stone, Bryan, Uchida, Derek A, Johnson, Joseph, Reynolds, Carolyn, Valentine, Karen, Koopmeiners, Karmella, Kim, Eun Hea, Savitz, Lucy, Maloney, Christopher G

“…Gaps exist in inpatient asthma care. Our aims were to assess the impact of an evidence-based care process model (EB-CPM) 5 years after implementation at…”
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Inflammatory Myofibroblastic Tumor in the Airway of a Child by Uchida, Derek A., MD, Hawkins, John A., MD, Coffin, Cheryl M., MD, Grimmer, Johannes Fredrik, MD

“…This report describes a 9-year-old boy who was found to have an inflammatory myofibroblastic tumor completely occluding the right mainstem bronchus. Initial…”
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Ambulatory Management of Childhood Asthma Using a Novel Self-management Application by Nkoy, Flory L, Fassl, Bernhard A, Wilkins, Victoria L, Johnson, Joseph, Unsicker, Eun Hea, Koopmeiners, Karmella J, Jensen, Andrea, Frazier, Michelle, Gaddis, Jordan, Malmgren, Lis, Williams, Stacey, Oldroyd, Heather, Greene, Tom, Sheng, Xiaoming, Uchida, Derek A, Maloney, Christopher G, Stone, Bryan L

“…Pediatric ambulatory asthma control is suboptimal, reducing quality of life (QoL) and causing emergency department (ED) and hospital admissions. We assessed…”
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Activation of Transient Receptor Potential Ankyrin-1 by Insoluble Particulate Material and Association with Asthma by Deering-Rice, Cassandra E, Shapiro, Darien, Romero, Erin G, Stockmann, Chris, Bevans, Tatjana S, Phan, Quang M, Stone, Bryan L, Fassl, Bernhard, Nkoy, Flory, Uchida, Derek A, Ward, Robert M, Veranth, John M, Reilly, Christopher A

“…Inhaled irritants activate transient receptor potential ankyrin-1 (TRPA1), resulting in cough, bronchoconstriction, and inflammation/edema. TRPA1 is also…”
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Characterization of Transient Receptor Potential Vanilloid-1 (TRPV1) Variant Activation by Coal Fly Ash Particles and Associations with Altered Transient Receptor Potential Ankyrin-1 (TRPA1) Expression and Asthma by Deering-Rice, Cassandra E., Stockmann, Chris, Romero, Erin G., Lu, Zhenyu, Shapiro, Darien, Stone, Bryan L., Fassl, Bernhard, Nkoy, Flory, Uchida, Derek A., Ward, Robert M., Veranth, John M., Reilly, Christopher A.

“…Transient receptor potential (TRP) channels are activated by environmental particulate materials. We hypothesized that polymorphic variants of transient…”
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The Joint Commission Children's Asthma Care Quality Measures and Asthma Readmissions by FASSL, Bernhard A, NKOY, Flory L, STONE, Bryan L, SRIVASTAVA, Rajendu, SIMON, Tamara D, UCHIDA, Derek A, KOOPMEINERS, Karmella, GREENE, Tom, COOK, Lawrence J, MALONEY, Christopher G

“…The Joint Commission introduced 3 Children's Asthma Care (CAC 1-3) measures to improve the quality of pediatric inpatient asthma care. Validity of the…”
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Late Presentation of Double Aortic Arch in School-Age Children Presumed to Have Asthma: The Benefits of Spirometry and Examination of the Flow-Volume Curve by UCHIDA, Derek A

“…Children with double aortic arch most often present in infancy. This report presents 3 patients in whom the diagnosis of double aortic arch was not revealed…”
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Longitudinal validation of a tool for asthma self-monitoring by Nkoy, Flory L, Stone, Bryan L, Fassl, Bernhard A, Uchida, Derek A, Koopmeiners, Karmella, Halbern, Sarah, Kim, Eun H, Wilcox, Allison, Ying, Jian, Greene, Tom H, Mosen, David M, Schatz, Michael N, Maloney, Christopher G

“…To establish longitudinal validation of a new tool, the Asthma Symptom Tracker (AST). AST combines weekly use of the Asthma Control Test with a color-coded…”
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Contextual Factors Influencing Implementation of Evidence-Based Care for Children Hospitalized With Asthma by Nkoy, Flory L, Wilkins, Victoria L, Fassl, Bernhard A, Johnson, Joseph M, Uchida, Derek A, Poll, Justin B, Greene, Tom H, Koopmeiners, Karmella J, Reynolds, Carolyn C, Valentine, Karen J, Savitz, Lucy A, Maloney, Christopher G, Stone, Bryan L

“…The translation of research findings into routine care remains slow and challenging. We previously reported successful implementation of an asthma…”
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Pulmonary nodules in a newborn with ATP-binding cassette transporter A3 (ABCA3) mutations by Uchida, Derek A, Wert, Susan E, Nogee, Lawrence M, Carroll, Travis R, Chatfield, Barbara A

“…Mutations in the gene for adenosine triphosphate-binding cassette transporter A3 (ABCA3) have been reported in infants and children with fatal surfactant…”
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Persistent Left Superior Vena Cava in a Child Presenting With Mild Hypoxemia by Uchida, Derek A., Cowley, Collin G., Feola, G. Peter, Williams, Richard V.

“…When present, a persistent left superior vena cava (LSVC) in most cases drains into the right atrium via an intact coronary sinus and there are no clinical…”
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Infarction of an extralobar pulmonary sequestration in a young child: diagnosis and excision by video-assisted thoracoscopy by Uchida, Derek A, Moore, Kevin R, Wood, Kelly E, Pysher, Theodore J, Downey, Earl C

“…A 4-year-old male presented with abdominal pain. A computed tomography scan of the abdomen was negative, but a pleural effusion and mass was noted in the lower…”
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Congenital Tracheal Stenosis Masquerading as Asthma in an Adolescent: The Value of Spirometry by Uchida, Derek A., Morgan-Wallace, Valerie, Richards, Kathleen, Seidelman, Jeanette, Muntz, Harlan R.

“…Congenital tracheal stenosis is a rare condition with a variable age of presentation. Severe stenosis results in significant respiratory symptoms during…”
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Pulmonary nodules in a newborn with ATP-binding cassette transporter A3 by Uchida, Derek A, Wert, Susan E, Nogee, Lawrence M, Carroll, Travis R, Chatfield, Barbara A

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Activation of Transient Receptor Potential Ankyrin-1 by Insoluble Particulate Material and Association with Asthma by Deering-Rice, Cassandra E, Shapiro, Darien, Romero, Erin G, Stockmann, Chris, Bevans, Tatjana S, Phan, Quang M, Stone, Bryan L, Fassl, Bernhard, Nkoy, Flory, Uchida, Derek A, Ward, Robert M, Veranth, John M, Reilly, Christopher A

“…Inhaled irritants activate transient receptor potential ankyrin-1 (TRPA1), resulting in cough, bronchoconstriction, and inflammation/edema. TRPA1 is also…”
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Cationic proteins increase the permeability of cultured rabbit tracheal epithelial cells: modification by heparin and extracellular calcium by Uchida, D A, Irvin, C G, Ballowe, C, Larsen, G, Cott, G R

“…Airway inflammation is a consistent finding in asthma, and increased amounts of eosinophil-derived cationic proteins are present in bronchoalveolar lavage…”
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The effect of human eosinophil granule major basic protein on airway responsiveness in the rat in vivo. A comparison with polycations by Uchida, D A, Ackerman, S J, Coyle, A J, Larsen, G L, Weller, P F, Freed, J, Irvin, C G

“…Major basic protein (MBP) is a highly cationic protein found in the granules of eosinophils. It has been postulated that MBP may participate in the…”
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