Search Results - "Uche, Fidelia Ijeoma"

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  1. 1

    Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study by Cao, Pan, Yang, Ying, Uche, Fidelia Ijeoma, Hart, Sarah Ruth, Li, Wen-Wu, Yuan, Chengqing

    “…Modification of metal surfaces with antimicrobial peptides is a promising approach to reduce bacterial adhesion. Here, cyclic peptides or cycloids, possessing…”
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    Journal Article
  2. 2

    Antinociceptive and anti-inflammatory activities of crude extracts of Ipomoea involucrata leaves in mice and rats by Ijeoma, Uche Fidelia, Aderonke, Shorinwa Olusayo, Ogbonna, Okorie, Augustina, Mgbahurike Amaka, Ifeyinwa, Chijioke-Nwauche

    Published in Asian Pacific journal of tropical medicine (01-02-2011)
    “…To investigate antinociceptive and anti-inflammatory activities of crude extract from Ipomoea involucrata leaves (Convolvulaceae) in mice and rats. The…”
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    Journal Article
  3. 3

    In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues by Uche, Fidelia Ijeoma, Guo, Xiaozhen, Okokon, Jude, Ullah, Imran, Horrocks, Paul, Boateng, Joshua, Huang, Chenggang, Li, Wen-Wu

    Published in Antimicrobial agents and chemotherapy (20-01-2021)
    “…Bisbenzylisoquinoline (BBIQ) alkaloids are a diverse group of natural products that demonstrate a range of biological activities. In this study, the…”
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    Journal Article
  4. 4

    Synthesis of (aminoalkyl)cycleanine analogues: cytotoxicity, cellular uptake, and apoptosis induction in ovarian cancer cells by Uche, Fidelia Ijeoma, McCullagh, James, Claridge, Timothy W.D., Richardson, Alan, Li, Wen-Wu

    Published in Bioorganic & medicinal chemistry letters (15-05-2018)
    “…[Display omitted] Our previous studies demonstrated that cycleanine, a macrocyclic bisbenzylisoquinoline (BBIQ) alkaloid, showed potent anti-ovarian cancer…”
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    Journal Article
  5. 5

    Isochondodendrine and 2′-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell lines by Uche, Fidelia Ijeoma, Abed, Mohammed N., Abdullah, Marwan I., Drijfhout, Falko P., McCullagh, James, Claridge, Timothy W. D., Richardson, Alan, Li, Wen-Wu

    Published in RSC advances (2017)
    “…Triclisia subcordata Oliv (Menispermeaceae) is used in herbal medicine for the treatment of cancer and other diseases in Africa. This study aims to isolate…”
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    Journal Article
  6. 6

    Phytochemical analysis and evaluation of anticancer and antimalarial properties of four medicinal plants by Uche, Fidelia Ijeoma

    Published 01-01-2017
    “…Cancer and malaria are among the most life-threatening diseases globally. Cancer is responsible for about 125,000 annual deaths globally. In 2015, the World…”
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    Dissertation
  7. 7