Search Results - "Uche, Fidelia Ijeoma"
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Coupling Plant-Derived Cyclotides to Metal Surfaces: An Antibacterial and Antibiofilm Study
Published in International journal of molecular sciences (09-03-2018)“…Modification of metal surfaces with antimicrobial peptides is a promising approach to reduce bacterial adhesion. Here, cyclic peptides or cycloids, possessing…”
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Journal Article -
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Antinociceptive and anti-inflammatory activities of crude extracts of Ipomoea involucrata leaves in mice and rats
Published in Asian Pacific journal of tropical medicine (01-02-2011)“…To investigate antinociceptive and anti-inflammatory activities of crude extract from Ipomoea involucrata leaves (Convolvulaceae) in mice and rats. The…”
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In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
Published in Antimicrobial agents and chemotherapy (20-01-2021)“…Bisbenzylisoquinoline (BBIQ) alkaloids are a diverse group of natural products that demonstrate a range of biological activities. In this study, the…”
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Synthesis of (aminoalkyl)cycleanine analogues: cytotoxicity, cellular uptake, and apoptosis induction in ovarian cancer cells
Published in Bioorganic & medicinal chemistry letters (15-05-2018)“…[Display omitted] Our previous studies demonstrated that cycleanine, a macrocyclic bisbenzylisoquinoline (BBIQ) alkaloid, showed potent anti-ovarian cancer…”
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Isochondodendrine and 2′-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell lines
Published in RSC advances (2017)“…Triclisia subcordata Oliv (Menispermeaceae) is used in herbal medicine for the treatment of cancer and other diseases in Africa. This study aims to isolate…”
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Phytochemical analysis and evaluation of anticancer and antimalarial properties of four medicinal plants
Published 01-01-2017“…Cancer and malaria are among the most life-threatening diseases globally. Cancer is responsible for about 125,000 annual deaths globally. In 2015, the World…”
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Dissertation -
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Isochondodendrine and 2′-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell linesThis study is presented at the 5th International Conference on the Mechanism of Action of Nutraceuticals, Aberdeen, UK.Electronic supplementary information (ESI) available. See DOI: 10.1039/c7ra08032h
Published 12-09-2017“…Triclisia subcordata Oliv (Menispermeaceae) is used in herbal medicine for the treatment of cancer and other diseases in Africa. This study aims to isolate…”
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Journal Article