Search Results - "Ubezio, Gianluca"

Identification of a novel cord blood NK cell subpopulation expressing functional programmed death receptor-1 by Greppi, Marco, Obino, Valentina, Goda, Rayan, Rebaudi, Federico, Carlomagno, Simona, Della Chiesa, Mariella, Sivori, Simona, Ubezio, Gianluca, Agostini, Vanessa, Bo, Alessandra, Pesce, Silvia, Marcenaro, Emanuela

“…Natural Killer cells (NKs) represent the innate counterpart of TCRαβ lymphocytes and are characterized by a high anti-tumor and an anti-viral cytotoxic…”
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Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements by Bagnara, Davide, Colombo, Monica, Reverberi, Daniele, Matis, Serena, Massara, Rosanna, Cardente, Niccolò, Ubezio, Gianluca, Agostini, Vanessa, Agnelli, Luca, Neri, Antonino, Cardillo, Martina, Vergani, Stefano, Ghiotto, Fabio, Mazzarello, Andrea Nicola, Morabito, Fortunato, Cutrona, Giovanna, Ferrarini, Manlio, Fais, Franco

“…Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of monoclonal CD5 + B cells with low surface immunoglobulins (IG). About 40% of CLL…”
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“Normal values” for the lymphocyte cytokinesis-block micronucleus cytome parameters: Repeatability and reproducibility in a healthy reference population by Bolognesi, Claudia, Bonelli, Luigina, Compalati, Andrea, Ferla, Valentina, Stagnaro, Laura, Ubezio, Gianluca, Bruzzi, Paolo

“…The micronucleus test in peripheral blood lymphocytes is the most widely validated technique to evaluate the DNA damage and chromosomal instability in human…”
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Granulocytes and monocytes apheresis induces upregulation of TGFβ1 in patients with active ulcerative colitis: A possible involvement of soluble HLA‐I by Contini, Paola, Negrini, Simone, Bodini, Giorgia, Trucchi, Cecilia, Ubezio, Gianluca, Strada, Paolo, Savarino, Vincenzo, Ghio, Massimo

“…Granulocyte and monocyte apheresis has been used in different immune‐mediated disorders, mainly inflammatory bowel diseases. The removal of activated…”
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Granulocytes and monocytes apheresis induces upregulation of TGFβ 1 in patients with active ulcerative colitis: A possible involvement of soluble HLA-I by Contini, Paola, Negrini, Simone, Bodini, Giorgia, Trucchi, Cecilia, Ubezio, Gianluca, Strada, Paolo, Savarino, Vincenzo, Ghio, Massimo

“…Granulocyte and monocyte apheresis has been used in different immune-mediated disorders, mainly inflammatory bowel diseases. The removal of activated…”
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Granulocytes and monocytes apheresis induces upregulation of TGF[beta]1 in patients with active ulcerative colitis: A possible involvement of soluble HLA-I by Contini, Paola, Negrini, Simone, Bodini, Giorgia, Trucchi, Cecilia, Ubezio, Gianluca, Strada, Paolo, Savarino, Vincenzo, Ghio, Massimo

“…Granulocyte and monocyte apheresis has been used in different immune-mediated disorders, mainly inflammatory bowel diseases. The removal of activated…”
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Immunomodulation due to plasma or plasma-platelet apheresis donation: Events occurring during donation procedures by Ghio, Massimo, Contini, Paola, Ansaldi, Filippo, Ubezio, Gianluca, Setti, Maurizio, Risso, Marco, Tripodi, Gino

“…Background: It has been recently shown that during therapeutic apheresis procedure, a large amount of soluble HLA class I molecules settles onto plastic…”
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Ambulatory Management of Anemia: A Retrospective View from an Italian Multidisciplinary Team by Arboscello, Eleonora, Molinari, Elisa, Tolomeo, Francesco, Del Corso, Lisette, Vignolo, Luana, Ubezio, Gianluca, Carlier, Paolo, Strada, Paolo, Ghio, Riccardo, Puppo, Francesco, Mangini, Paola, Beltramini, Sabrina, Dulbecco, Pietro, Anserini, Paola, van Lint, Maria Teresa, Bacigalupo, Andrea, Guolo, Fabio, Clavio, Marino, Bellodi, Andrea

“…Anemia is one of the most prevalent clinic condition leading to a specialist medical consult. In 2014 our Internal Medicine unit started a Multidisciplinary…”
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Transient transforming growth factor β1 modulation in monocytes and natural killer cells following plasma or plasma-platelet apheresis donation procedures by Ghio, Massimo, Contini, Paola, Ubezio, Gianluca, Ansaldi, Filippo, Setti, Maurizio, Tripodi, Gino

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The Safety, Tolerability and Efficacy of Deferasirox in Older Patients with Transfusional Dependent Anemia by Arboscello, Eleonora, Del Corso, Lisette, Agnelli Giacchello, Jacopo, Balleari, Enrico, Bellodi, Andrea, Di Grazia, Carmen, Dominietto, Alida, Favorini, Serena, Ghiso, Anna, Giovannini, Martina, Molinari, Elisa, Salvetti, Chiara, Sicbaldi, Vera, Strada, Paolo, Ubezio, Gianluca, Van Lint, Maria Teresa, Vignolo, Luana, Ghio, Riccardo

“…Background The majority of myelodysplastic syndrome (MDS), primary myelofibrosis (MPN) and aplastic anemia (AA) patients during the course of the disease…”
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Transient inhibition of neutrophil migration following plasma or plasma-platelet apheresis donation procedures by Ghio, Massimo, Bertolotto, Maria, Ottonello, Luciano, Contini, Paola, Ubezio, Gianluca, Tripodi, Gino

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Multidisciplinary Evaluation Improves Efficacy and Safety of Iron Chelation Therapy with Deferasirox in MDS Elderly Patients by Del Corso, Lisette, Molinari, Elisa, Bellodi, Andrea, Ghio, Riccardo, Bacigalupo, Andrea, van Lint, Maria Teresa, Di Grazia, Carmen, Clavio, Marino, Ubezio, Gianluca, Russo, Rodolfo, Tassara, Rodolfo, Scudeletti, Marco, Calzamiglia, Tullio, Filiberti, Rosa, Brunofranco, Massimiliano, Goretti, Riccardo, Simonetti, Federico, Rousseau, Martina, Galimberti, Sara, Schilardi, Matteo, Biale, Lucia, Arboscello, Eleonora

“…BACKGROUND: Iron overload from chronic transfusion therapy can be extremely toxic and most patients (pts) do not receive adequate iron chelation therapy (ICT)…”
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A possible role of soluble HLA-I molecule in the immunomodulatory effects of therapeutic apheresis by Ghio, Massimo, Contini, Paola, Ansaldi, Filippo, Ubezio, Gianluca, Setti, Maurizio, Risso, Marco, Tripodi, Gino

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Contact with the bone marrow microenvironment readdresses the fate of transplanted hematopoietic stem cells by Massollo, Michela, Podestà, Marina, Marini, Cecilia, Morbelli, Silvia, Cassanelli, Clara, Pinto, Valeria, Ubezio, Gianluca, Curti, Giovanna, Uccelli, Antonio, Frassoni, Francesco, Sambuceti, Gianmario

“…Objective Despite enormous advancements in our comprehension of molecular mechanisms governing hematopoietic stem cells (HSCs) engraftment in the bone marrow,…”
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Donor neutrophil activation and transforming growth factor-β1 modulation induced by donor apheresis procedures by Ghio, Massimo, Contini, Paola, Ansaldi, Filippo, Ubezio, Gianluca, Setti, Maurizio, Risso, Marco, Tripodi, Gino

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Blood transfusions with high levels of contaminating soluble HLA-I correlate with levels of soluble CD8 in recipients' plasma; a new control factor in soluble HLA-I-mediated transfusion-modulated immunomodulation? by Ghio, Massimo, Contini, Paola, Ubezio, Gianluca, Ansaldi, Filippo, Setti, Maurizio, Tripodi, Gino

“…The cause of transfusion-related immunomodulation (TRIM) has proved tantalisingly elusive. An ever-growing body of evidence indicates that the infusion of…”
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sHLA-I contaminating molecules as novel mechanism of ex vivo/in vitro transcriptional and posttranscriptional modulation of transforming growth factor-beta in CD8+ T lymphocytes and neutrophils after intravenous immunoglobulin treatment by Ghio, Massimo, Contini, Paola, Negrini, Simone, Proietti, Michele, Gonella, Roberta, Ubezio, Gianluca, Ottonello, Luciano, Indiveri, Francesco

“…Numerous mechanisms have been proposed to explain the beneficial action of intravenous immune globulin (IVIG) in autoimmune and systemic inflammatory…”
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Bio-modulators in platelet-rich plasma: a comparison of the amounts in products from healthy donors and patients produced with three different techniques by Ubezio, Gianluca, Ghio, Massimo, Contini, Paola, Bertorello, Roberta, Marino, Gennaro, Tomasini, Andrea, Tripodi, Gino

“…Platelet-rich plasma consists of platelets concentrated in a small volume of plasma and constitutes a reservoir of bio-modulators potentially useful in tissue…”
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Immunomodulatory effects of blood transfusions: the synergic role of soluble HLA Class I free heavy-chain molecules detectable in blood components by Ghio, Massimo, Contini, Paola, Ubezio, Gianluca, Mazzei, Clemente, Puppo, Franco, Indiveri, Franco

“…BACKGROUND: Over the past decades, the weight of the published literature demonstrates that blood transfusions can induce clinically significant…”
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sHLA-I Contamination, A Novel Mechanism to Explain Ex Vivo/In Vitro Modulation of IL-10 Synthesis and Release in CD8⁺ T Lymphocytes and in Neutrophils Following Intravenous Immunoglobulin Infusion by Ghio, Massimo, Contini, Paola, Setti, Maurizio, Ubezio, Gianluca, Mazzei, Clemente, Tripodi, Gino

“…Background Numerous mechanisms have been proposed to explain the beneficial action of intravenous immune globulin (IVIG) in autoimmune and systemic…”
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