Search Results - "Ubelmann, Florent"

Actin dynamics counteract membrane tension during clathrin-mediated endocytosis by Kirchhausen, Tomas, Boulant, Steeve, Kural, Comert, Zeeh, Jean-Christophe, Ubelmann, Florent

“…Clathrin-mediated endocytosis is independent of actin dynamics in many circumstances but requires actin polymerization in others. We show that membrane tension…”
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Enterocyte loss of polarity and gut wound healing rely upon the F-actin—severing function of villin by Ubelmann, Florent, Chamaillard, Mathias, El-Marjou, Fatima, Simon, Anthony, Netter, Jeanne, Vignjevic, Danijela, Nichols, Buford L., Quezada-Calvillo, Roberto, Grandjean, Teddy, Louvard, Daniel, Revenu, Céline, Robine, Sylvie

“…Efficient wound healing is required to maintain the integrity of the intestinal epithelial barrier because of its constant exposure to a large variety of…”
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Measuring the Endocytic Recycling of Amyloid Precursor Protein (APP) in Neuro2a Cells by Ubelmann, Florent, Burrinha, Tatiana, Almeida, Claudia Guimas

“…The established primary trigger of Alzheimer's disease's is β-amyloid (Aβ) (Mucke and Selkoe, 2012). Amyloid precursor protein (APP) endocytosis is required…”
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A Novel Protocol to Quantitatively Measure the Endocytic Trafficking of Amyloid Precursor Protein (APP) in Polarized Primary Neurons with Sub-cellular Resolution by Ubelmann, Florent, Burrinha, Tatiana, Almeida, Claudia Guimas

“…Alzheimer's disease's established primary trigger is β-amyloid (Aβ) (Mucke and Selkoe, 2012). The amyloid precursor protein (APP) endocytosis is required for…”
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Bin1 and CD2AP polarise the endocytic generation of beta‐amyloid by Ubelmann, Florent, Burrinha, Tatiana, Salavessa, Laura, Gomes, Ricardo, Ferreira, Cláudio, Moreno, Nuno, Guimas Almeida, Cláudia

“…The mechanisms driving pathological beta‐amyloid (Aβ) generation in late‐onset Alzheimer's disease (AD) are unclear. Two late‐onset AD risk factors, Bin1 and…”
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Abstract 4078: Acquired resistance to PARP inhibitors evolves from drug-tolerant cells vulnerable to AsiDNA by Jdey, Wael, Calvayrac, Olivier, Maloudi, Orlane, Ubelmann, Florent, Favre, Gilles, Bono, Françoise

“…Abstract Purpose: PARP inhibitors (PARPi) resistance remains a major clinical hurdle as virtually all patients treated with PARPi will eventually relapse. We…”
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Apical Invasion of Intestinal Epithelial Cells by Salmonella typhimurium Requires Villin to Remodel the Brush Border Actin Cytoskeleton by Lhocine, Nouara, Arena, Ellen T., Bomme, Perrine, Ubelmann, Florent, Prévost, Marie-Christine, Robine, Sylvie, Sansonetti, Philippe J.

“…Salmonella invasion of intestinal epithelial cells requires extensive, though transient, actin modifications at the site of bacterial entry. The…”
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A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins by Revenu, Céline, Ubelmann, Florent, Hurbain, Ilse, El-Marjou, Fatima, Dingli, Florent, Loew, Damarys, Delacour, Delphine, Gilet, Jules, Brot-Laroche, Edith, Rivero, Francisco, Louvard, Daniel, Robine, Sylvie

“…Actin-bundling proteins are identified as key players in the morphogenesis of thin membrane protrusions. Until now, functional redundancy among the…”
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Bin1 and CD 2 AP polarise the endocytic generation of beta‐amyloid by Ubelmann, Florent, Burrinha, Tatiana, Salavessa, Laura, Gomes, Ricardo, Ferreira, Cláudio, Moreno, Nuno, Guimas Almeida, Cláudia

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