Search Results - "Ubaldi, Massimo"

Nuclear peroxisome proliferator activated receptor-gamma (PPARγ) as a therapeutic target to treat neurodegeneration and dependence elicited by drugs of abuse by Ciccocioppo, Roberto, Ubaldi, Massimo

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NOP receptor antagonism attenuates reinstatement of alcohol-seeking through modulation of the mesolimbic circuitry in male and female alcohol-preferring rats by Borruto, Anna Maria, Fotio, Yannick, Stopponi, Serena, Petrella, Michele, De Carlo, Sara, Domi, Ana, Ubaldi, Massimo, Weiss, Friedbert, Ciccocioppo, Roberto

“…In patients suffering from alcohol use disorder (AUD), stress and environmental stimuli associated with alcohol availability are important triggers of relapse…”
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Encapsulation of Carlina acaulis essential oil and carlina oxide to develop long-lasting mosquito larvicides: microemulsions versus nanoemulsions by Pavela, Roman, Pavoni, Lucia, Bonacucina, Giulia, Cespi, Marco, Cappellacci, Loredana, Petrelli, Riccardo, Spinozzi, Eleonora, Aguzzi, Cristina, Zeppa, Laura, Ubaldi, Massimo, Desneux, Nicolas, Canale, Angelo, Maggi, Filippo, Benelli, Giovanni

“…Carlina acaulis root essential oil (EO) is one of the most potent mosquito larvicides (LC 50  < 2 ppm). This EO is mainly composed of carlina oxide (> 90%)…”
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Effect of Glucocorticoid Receptor Antagonism on Alcohol Self-Administration in Genetically-Selected Marchigian Sardinian Alcohol-Preferring and Non-Preferring Wistar Rats by Benvenuti, Federica, Cannella, Nazzareno, Stopponi, Serena, Soverchia, Laura, Ubaldi, Massimo, Lunerti, Veronica, Vozella, Valentina, Cruz, Bryan, Roberto, Marisa, Ciccocioppo, Roberto

“…Alcoholism is a chronically relapsing disorder characterized by high alcohol intake and a negative emotional state during abstinence, which contributes to…”
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Role of Nociceptin/Orphanin FQ-NOP Receptor System in the Regulation of Stress-Related Disorders by Ubaldi, Massimo, Cannella, Nazzareno, Borruto, Anna Maria, Petrella, Michele, Micioni Di Bonaventura, Maria Vittoria, Soverchia, Laura, Stopponi, Serena, Weiss, Friedbert, Cifani, Carlo, Ciccocioppo, Roberto

“…Nociceptin/orphanin FQ (N/OFQ) is a 17-residue neuropeptide that binds the nociceptin opioid-like receptor (NOP). N/OFQ exhibits nucleotidic and aminoacidics…”
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Further evidence for the involvement of the PPARγ system on alcohol intake and sensitivity in rodents by Domi, Esi, Domi, Ana, Ubaldi, Massimo, Somaini, Lorenzo, Demopulos, Gregory, Gaitanaris, George, Ciccocioppo, Roberto

“…Rationale Peroxisome Proliferator Activator receptors (PPARs) are intracellular receptors that function as transcription factors, which regulate specific…”
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Dysregulation of Nociceptin/Orphanin FQ and Dynorphin Systems in the Extended Amygdala of Alcohol Preferring Marchigian Sardinian (msP) Rats by Caputi, Francesca Felicia, Stopponi, Serena, Rullo, Laura, Palmisano, Martina, Ubaldi, Massimo, Candeletti, Sanzio, Ciccocioppo, Roberto, Romualdi, Patrizia

“…Previous studies have shown that genetically selected Marchigian Sardinian alcohol-preferring (msP) rats consume excessive amounts of ethanol to self-medicate…”
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A2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable? by Spinaci, Andrea, Lambertucci, Catia, Buccioni, Michela, Dal Ben, Diego, Graiff, Claudia, Barbalace, Maria Cristina, Hrelia, Silvana, Angeloni, Cristina, Tayebati, Seyed Khosrow, Ubaldi, Massimo, Masi, Alessio, Klotz, Karl-Norbert, Volpini, Rosaria, Marucci, Gabriella

“…The A2A adenosine receptor (A2AAR) is one of the four subtypes activated by nucleoside adenosine, and the molecules able to selectively counteract its action…”
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Administration of Linoleoylethanolamide Reduced Weight Gain, Dyslipidemia, and Inflammation Associated with High-Fat-Diet-Induced Obesity by Tovar, Rubén, de Ceglia, Marialuisa, Ubaldi, Massimo, Rodríguez-Pozo, Miguel, Soverchia, Laura, Cifani, Carlo, Rojo, Gema, Gavito, Ana, Hernandez-Folgado, Laura, Jagerovic, Nadine, Ciccocioppo, Roberto, Baixeras, Elena, Rodríguez de Fonseca, Fernando, Decara, Juan

“…Acylethanolamides (NAEs) are bioactive lipids derived from diet fatty acids that modulate important homeostatic functions, including appetite, fatty acid…”
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Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition by Cippitelli, Andrea, Astarita, Giuseppe, Duranti, Andrea, Caprioli, Giovanni, Ubaldi, Massimo, Stopponi, Serena, Kallupi, Marsida, Sagratini, Gianni, Rodrìguez de Fonseca, Fernando, Piomelli, Daniele, Ciccocioppo, Roberto

“…Evidence shows that the endocannabinoid system modulates the addictive properties of nicotine. In the present study, we hypothesized that spontaneous…”
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Multi-dimensional characterization of an alcohol dependence-prone phenotype in rats by Ana, Domi, Roberto, Ciccocioppo, Nazzareno, Cannella, Massimo, Ubaldi

“…In this study, we adapted the DSM-IV/5 based three-criteria model of cocaine addiction to study individual differences in alcohol dependence in rats. Rats were…”
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A Role for Neuropeptide S in Alcohol and Cocaine Seeking by Cannella, Nazzareno, Borruto, Anna Maria, Petrella, Michele, Micioni Di Bonaventura, Maria Vittoria, Soverchia, Laura, Cifani, Carlo, De Carlo, Sara, Domi, Esi, Ubaldi, Massimo

“…The neuropeptide S (NPS) is the endogenous ligand of the NPS receptor (NPSR). The NPSR is widely expressed in brain regions that process emotional and…”
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Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system by Kallupi, Marsida, Cannella, Nazzareno, Economidou, Daina, Ubaldi, Massimo, Ruggeri, Barbara, Weiss, Friedbert, Massi, Maurizio, Marugan, Juan, Heilig, Markus, Bonnavion, Patricia, de Lecea, Luis, Ciccocioppo, Roberto, Bloom, Floyd

“…Drug addiction is a chronic relapsing disorder characterized by compulsive drug seeking and use. Environmental conditioning factors are among the major…”
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The Neural Network of Neuropeptide S (NPS): Implications in Food Intake and Gastrointestinal Functions by Botticelli, Luca, Micioni Di Bonaventura, Emanuela, Ubaldi, Massimo, Ciccocioppo, Roberto, Cifani, Carlo, Micioni Di Bonaventura, Maria Vittoria

“…The Neuropeptide S (NPS), a 20 amino acids peptide, is recognized as the endogenous ligand of a previously orphan G protein-coupled receptor, now termed NPS…”
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Network-Based Discovery of Opioid Use Vulnerability in Rats Using the Bayesian Stochastic Block Model by Allen, Carter, Kuhn, Brittany N, Cannella, Nazzareno, Crow, Ayteria D, Roberts, Analyse T, Lunerti, Veronica, Ubaldi, Massimo, Hardiman, Gary, Solberg Woods, Leah C, Ciccocioppo, Roberto, Kalivas, Peter W, Chung, Dongjun

“…Opioid use disorder is a psychological condition that affects over 200,000 people per year in the U.S., causing the Centers for Disease Control and Prevention…”
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Acute stress enhances the expression of neuroprotection- and neurogenesis-associated genes in the hippocampus of a mouse restraint model by Sannino, Giuseppina, Pasqualini, Lorenza, Ricciardelli, Eugenia, Montilla, Patricia, Soverchia, Laura, Ruggeri, Barbara, Falcinelli, Silvia, Renzi, Alessandra, Ludka, Colleen, Kirchner, Thomas, Grünewald, Thomas G P, Ciccocioppo, Roberto, Ubaldi, Massimo, Hardiman, Gary

“…Stress arises from an external demand placed on an organism that triggers physiological, cognitive and behavioural responses in order to cope with that…”
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Ötzi's Last Meals: DNA Analysis of the Intestinal Content of the Neolithic Glacier Mummy from the Alps by Rollo, Franco, Ubaldi, Massimo, Ermini, Luca, Marota, Isolina

“…Samples of the intestinal content were collected from the ileum and colon of the Neolithic glacier mummy popularly known as the Tyrolean Iceman, or Ötzi. DNA…”
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Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain by Wang, Yijing, Blom, Elin S., Skoglund, Lena, Hansson, Anita C., Ubaldi, Massimo, Lourdusamy, Anbarasu, Sommer, Wolfgang H., Mielke, Matthew, Hyman, Bradley T., Heilig, Markus, Lannfelt, Lars, Nilsson, Lars N. G., Ingelsson, Martin

“…Several components in the Wnt pathway, including β-catenin and glycogen synthase kinase 3 beta, have been implied in AD pathogenesis. Here, mRNA brain levels…”
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Genetic deletion or pharmacological blockade of nociceptin/orphanin FQ receptors in the ventral tegmental area attenuates nicotine‐motivated behaviour by Domi, Ana, Lunerti, Veronica, Petrella, Michele, Domi, Esi, Borruto, Anna Maria, Ubaldi, Massimo, Weiss, Friedbert, Ciccocioppo, Roberto

“…Background and Purpose The nociceptin/orphanin FQ (N/OFQ)–nociceptin opioid‐like peptide (NOP) receptor system is widely distributed in the brain and…”
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Building better strategies to develop new medications in Alcohol Use Disorder: Learning from past success and failure to shape a brighter future by Cannella, Nazzareno, Ubaldi, Massimo, Masi, Alessio, Bramucci, Massimo, Roberto, Marisa, Bifone, Angelo, Ciccocioppo, Roberto

“…•The complexity of Alcohol Use Disorder offer the opportunity to explore new targets.•The most promising drug targets for alcohol addiction are…”
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