Search Results - "UTOGUCHI, N"

A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob by MIZUGUCHI, H, KOIZUMI, N, HOSONO, T, UTOGUCHI, N, WATANABE, Y, KAY, M. A, HAYAKAWA, T

“…The use of recombinant adenovirus (Ad) vectors containing genetically modified capsid proteins is an attractive strategy for achieving targeted gene transfer…”
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CAR- or αv integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice by MIZUGUCHI, H, KOIZUMI, N, HOSONO, T, ISHII-WATABE, A, UCHIDA, E, UTOGUCHI, N, WATANABE, Y, HAYAKAWA, T

“…Targeted gene delivery to the tissue of interest by recombinant adenovirus (Ad) vectors is limited by the relatively broad expression of the primary receptor,…”
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The Combination Therapy of Therapeutic Ultrasound and Dendritic Cell-Based Immunotherapy by Suzuki, R, Oda, Y, Koshima, R, Hirata, K, Nomura, T, Utoguchi, N, Maruyama, K

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Efflux transporter mRNA expression profiles in differentiating JEG-3 human choriocarcinoma cells as a placental transport model by Ikeda, K, Yamasaki, K, Homemoto, M, Yamaue, S, Ogawa, M, Nakao, E, Fukunaga, Y, Nakanishi, T, Utoguchi, N, Myotoku, M, Hirotani, Y

“…The kinetics of drug transport across the trophoblast layer is determined by several factors. Human choriocarcinoma cell lines like BeWo and JEG-3 have been…”
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Efficient gene transfer by fiber-mutant adenoviral vectors containing RGD peptide by Koizumi, Naoya, Mizuguchi, Hiroyuki, Hosono, Tetsuji, Ishii-Watabe, Akiko, Uchida, Eriko, Utoguchi, Naoki, Watanabe, Yoshiteru, Hayakawa, Takao

“…One of the hurdles to adenovirus (Ad)-mediated gene transfer is that Ad vectors mediate inefficient gene transfer into cells lacking in the primary receptors,…”
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Preparation of Rapidly Disintegrating Tablet Using New Types of Microcrystalline Cellulose (PH-M Series) and Low Substituted-Hydroxypropylcellulose or Spherical Sugar Granules by Direct Compression Method by ISHIKAWA, Tatsuya, MUKAI, Baku, SHIRAISHI, Shuji, UTOGUCHI, Naoki, FUJI, Makiko, MATSUMOTO, Mitsuo, WATANABE, Yoshiteru

“…To decrease the sensation of roughness when a tablet, which is rapidly disintegrated by saliva (rapidly disintegrating tablet), is orally taken, we prepared…”
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The effect of ethanol on the simultaneous transport and metabolism of methyl p-hydroxybenzoate in excised skin of Yucatan micropig by Oh, S.Y, Fujii, M, Takeda, Y, Yoda, K, Utoguchi, N, Matsumoto, M, Watanabe, Y

“…The effects of ethanol on the simultaneous transport and metabolism of methyl p-hydroxybenzoate (HBM) were investigated in the skin of Yucatan micropig in…”
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44 Vaccination of dendritic cells pulsed with tumor endothelial cells inhibits tumor growth by Utoguchi, N, Suzuki, R, Oda, Y, Nomura, T, Maruyama, K

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Characteristics of Transcription-regulatory Elements for Gene Expression from Plasmid Vectors in Human Trophoblast Cell Lines by Komiya, E., Kondoh, M., Mizuguchi, H., Fujii, M., Utoguchi, N., Nakanishi, T., Watanabe, Y.

“…Nonviral gene delivery systems are useful for basic research in trophoblasts. In these systems, gene expression is regulated by a cassette of regulatory…”
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Effect of forskolin on the expression of claudin-5 in human trophoblast BeWo cells by Harada, M, Kondoh, M, Masuyama, A, Fujii, M, Nakanishi, T, Utoguchi, N, Yagi, K, Watanabe, Y

“…Trophoblasts, a cell type found in the placenta, play a pivotal role in the function of the placenta as a barrier between the maternal fluid and the fetus…”
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Carrier-mediated Transport of Folic Acid in BeWo Cell Monolayers as a Model of the Human Trophoblast by Takahashi, T., Utoguchi, N., Takara, A., Yamamoto, N., Nakanishi, T., Tanaka, K., Audus, K.L., Watanabe, Y.

“…Using cultured BeWo cells as a model of human trophoblast, we investigated whether carrier-mediated transport of folic acid occurs. BeWo cells, which were…”
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Pharmacokinetics of Acetaminophen from Rapidly Disintegrating Compressed Tablet Prepared Using Microcrystalline Cellulose (PH-M-06) and Spherical Sugar Granules by ISHIKAWA, Tatsuya, KOIZUMI, Naoya, MUKAI, Baku, UTOGUCHI, Naoki, FUJII, Makiko, MATSUMOTO, Mitsuo, ENDO, Hisashi, SHIROTAKE, Shoichi, WATANABE, Yoshiteru

“…The aim of the present study was to evaluate the bioavailability of a drug from rapidly disintegrating tablets prepared using fine spherical crystalline…”
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Specific binding of TES-23 antibody to tumour vascular endothelium in mice, rats and human cancer tissue: A novel drug carrier for cancer targeting therapy by TSUNODA, S, OHIZUMI, I, HARADA, N, OHSUGI, Y, MAYUMI, T, MATSUI, J, KOIZUMI, K, WAKAI, Y, MAKIMOTO, H, TSUTSUMI, Y, UTOGUCHI, N, TANIGUCHI, K, SAITO, H

“…The tissue distribution of anti-tumour vascular endothelium monoclonal antibody (TES-23) produced by immunizing with plasma membrane vesicles from isolated rat…”
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Effect of tumour cell-conditioned medium on endothelial macromolecular permeability and its correlation with collagen by UTOGUCHI, N, MIZUGUCHI, H, DANTAKEAN, A, MAKIMOTO, H, WAKAI, Y, TSUTSUMI, Y, NAKAGAWA, S, MAYUMI, T

“…Conditioned medium prepared from mouse melanoma B16 cells (B16-CM) increases the macromolecular permeability of bovine aortic, venous and human umbilical vein…”
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Intracellular targeting of sodium mercaptoundecahydrododecaborate (BSH) to solid tumors by transferrin-PEG liposomes, for boron neutron-capture therapy (BNCT) by Maruyama, Kazuo, Ishida, Osamu, Kasaoka, Satoshi, Takizawa, Tomoko, Utoguchi, Naoki, Shinohara, Atsuko, Chiba, Momoko, Kobayashi, Hisao, Eriguchi, Masazumi, Yanagie, Hironobu

“…The successful treatment of cancer by boron neutron-capture therapy (BNCT) requires the selective delivery of relatively high concentration of 10B compounds to…”
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Trialkyltin Compounds Bind Retinoid X Receptor to Alter Human Placental Endocrine Functions by Nakanishi, Tsuyoshi, Nishikawa, Jun-ichi, Hiromori, Youhei, Yokoyama, Hideaki, Koyanagi, Mihoko, Takasuga, Shinri, Ishizaki, Jun-ichi, Watanabe, Mai, Isa, Shun-ichi, Utoguchi, Naoki, Itoh, Norio, Kohno, Yutaka, Nishihara, Tsutomu, Tanaka, Keiichi

“…Retinoid X receptor (RXR) is a nuclear receptor that plays important and multiple roles in mammalian development and homeostasis. We previously reported that,…”
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Generation of fiber-modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob by Koizumi, Naoya, Mizuguchi, Hiroyuki, Utoguchi, Naoki, Watanabe, Yoshiteru, Hayakawa, Takao

“…Background Fiber‐modified adenovirus (Ad) vectors can be effective in overcoming the limitations of conventional Ad vectors, specifically their inefficient…”
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Effective gene delivery with liposomal bubbles and ultrasound as novel non-viral system by Suzuki, Ryo, Takizawa, Tomoko, Negishi, Yoichi, Utoguchi, Naoki, Maruyama, Kazuo

“…We developed the novel liposomal bubbles (Bubble liposomes) containing ultrasound imaging gas, perfluoropropane. Bubble liposomes were made of pegylated…”
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Trialkyltin compounds enhance human CG secretion and aromatase activity in human placental choriocarcinoma cells by NAKANISHI, Tsuyoshi, KOHROKI, Junya, SUZUKI, Shizuko, ISHIZAKI, Junichi, HIROMORI, Youhei, TAKASUGA, Shinri, ITOH, Norio, WATANABE, Yoshiteru, UTOGUCHI, Naoki, TANAKA, Keiichi

“…Human choriocarcinoma cell lines have been used as placental models for the study of endocrine function, including aromatase (CYP19) activity and the secretion…”
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New method of preparing high-porosity rapidly saliva soluble compressed tablets using mannitol with camphor, a subliming material by Koizumi, Kei-ichi, Watanabe, Yoshiteru, Morita, Kumiko, Utoguchi, Naoki, Matsumoto, Mitsuo

“…Compressed tablets of a water-soluble material, prepared using mannitol, did not rapidly dissolve in water since it is difficult for water to penetrate into…”
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