Search Results - "UTKIN, Y. N"

Effect of Microgravity on the Crystallization of Cardiotoxin from the Venom of Spectacled Cobra Naja naja by Dubova, K. M., Dubovskii, P. V., Utkin, Y. N., Samygina, V. R.

“…Cardiotoxins, which belong to the family of three-finger toxins, are the main components of cobra venom. They exhibit various types of biological activity,…”
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α-Conotoxin RgIA and oligoarginine R8 in the mice model alleviate long-term oxaliplatin induced neuropathy by Dyachenko, I.A., Palikova, Yu A., Palikov, V.A., Korolkova, Y.V., Kazakov, V.A., Egorova, N.S., Garifulina, A.I., Utkin, Y.N., Tsetlin, V.I., Kryukova, E.V.

“…Оligoarginines were recently discovered (Lebedev et al., 2019 Nov) as a novel class of nicotinic acetylcholine receptors (nAChRs) inhibitors, octaoligoarginine…”
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Muscarinic and Nicotinic Acetylcholine Receptors in the Regulation of the Cardiovascular System by Osipov, A. V., Averin, A. S., Shaykhutdinova, E. R., Dyachenko, I. A., Tsetlin, V. I., Utkin, Y. N.

“…— Many different receptors and ion channels that regulate ion currents are involved in the control of the cardiovascular system (CVS). The functioning of the…”
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Cobra cytotoxins: structural organization and antibacterial activity by Dubovskii, P V, Utkin, Y N

“…Cardiotoxins (cytotoxins, CT) are β-structured proteins isolated from the venom of cobra. They consist of 59-61 amino acid residues, whose antiparallel chains…”
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Towards universal approach for bacterial production of three-finger Ly6/uPAR proteins: Case study of cytotoxin I from cobra N. oxiana by Shulepko, M.A., Lyukmanova, E.N., Shenkarev, Z.O., Dubovskii, P.V., Astapova, M.V., Feofanov, A.V., Arseniev, A.S., Utkin, Y.N., Kirpichnikov, M.P., Dolgikh, D.A.

“…Cytotoxins or cardiotoxins is a group of polycationic toxins from cobra venom belonging to the ‘three-finger’ protein superfamily (Ly6/uPAR family) which…”
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Intraspecific Variability in the Composition of the Venom from Monocled Cobra (Naja kaouthia) by Ryabinin, V. V., Ziganshin, R. H., Starkov, V. G., Tsetlin, V. I., Utkin, Y. N.

“…A proteomic analysis of the venom of males and females of the Naja kaouthia monocled cobra specimens kept in captivity was carried out. Using the amino acid…”
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First tryptophan-containing weak neurotoxin from cobra venom by UTKIN, Y. N, KUKHTINA, V. V, MASLENNIKOV, I. V, ELETSKY, A. V, STARKOV, V. G, WEISE, C, FRANKE, P, HUCHO, F, TSETLIN, V. I

“…With the purpose of studying structure-function relationships among weak neurotoxins (called so because of their low toxicity), we have isolated a toxin (WTX)…”
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Possible involvement of neuronal nicotinic acetylcholine receptors in compensatory brain mechanisms at early stages of Parkinson's disease by Kryukova, E V, Shelukhina, I V, Kolacheva, A A, Alieva, A Kh, Shadrina, M I, Slominsky, P A, Kasheverov, I E, Utkin, Y N, Ugrumov, M V, Tsetlin, V I

“…A role of nicotinic acetylcholine receptors (nAChR) in the development of Parkinson's disease (PD) has been investigated using two mouse models corresponding…”
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Possible involvement of neuronal nicotinic acetylcholine receptors in compensatory brain mechanisms at early stages of Parkinson’s disease by Kryukova, E. V., Shelukhina, I. V., Kolacheva, A. A., Alieva, A. Kh, Shadrina, M. I., Slominsky, P. A., Kasheverov, I. E., Utkin, Y. N., Ugrumov, M. V., Tsetlin, V. I.

“…A role of nicotinic acetylcholine receptors (nAChR) in the development of Parkinson’s disease (PD) has been investigated using two mouse models corresponding…”
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Nerve growth factor suppresses Ehrlich carcinoma growth by Osipov, A. V., Terpinskaya, T. I., Ulaschik, V. S., Tsetlin, V. I., Utkin, Y. N.

“…Currently, data on the antiproliferative effects of nerve growth factor (NGF) in vivo and its effect on breast tumor cells both in vivo and in vitro are…”
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"Weak toxin" from Naja kaouthia is a nontoxic antagonist of alpha 7 and muscle-type nicotinic acetylcholine receptors by Utkin, Y N, Kukhtina, V V, Kryukova, E V, Chiodini, F, Bertrand, D, Methfessel, C, Tsetlin, V I

“…A novel "weak toxin" (WTX) from Naja kaouthia snake venom competes with [(125)I]alpha-bungarotoxin for binding to the membrane-bound Torpedo californica…”
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Investigation of ligand binding sites of the acetylcholine receptor using photoactivatable derivatives of neurotoxin II from Naja naja oxiana by Kreienkamp, Hans Juergen, Utkin, Yu. N, Weise, Christoph, Machold, Jan, Tsetlin, V. I, Hucho, Ferdinand

“…Several photoaffinity derivatives of neurotoxin II from the venom of the central Asian cobra Naja naja oxiana have been prepared. After reaction of the…”
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Membrane binding motif of the P-type cardiotoxin by Dubovskii, Peter V., Dementieva, Daria V., Bocharov, Eduard V., Utkin, Yuri N., Arseniev, Alexander S.

“…Carditoxins (CTXs) from cobra snake venoms, the basic 60–62 residue all-beta sheet polypeptides, are known to bind to and impair the function of cell…”
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Weak neurotoxin from Naja kaouthia cobra venom affects haemodynamic regulation by acting on acetylcholine receptors by Ogay, Alexey Ya, Rzhevsky, Dmitry I., Murashev, Arkady N., Tsetlin, Victor I., Utkin, Yuri N.

“…Recent in vitro studies of weak neurotoxins from snake venoms have demonstrated their ability to interact with both muscle-type and neuronal α7 nicotinic…”
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Nicotinic receptors in Lymnaea stagnalis neurons are blocked by α-neurotoxins from cobra venoms by Vulfius, C.A., Krasts, I.V., Utkin, Yu.N., Tsetlin, V.I.

“…The influence of cobra neurotoxins on the Cl-dependent responses to acetylcholine (ACh) of Lymnaea neurons was studied by the voltage-clamp technique. It was…”
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Polyclonal antibodies against native weak toxin Naja kaouthia discriminate native weak toxins and some other three-fingered toxins against their denaturated forms by Kryukova, E.V., Mordvintsev, D.Yu, Daya, S., Utkin, Yu.N., Tsetlin, V.I.

“…Polyclonal antibodies obtained by immunization of rabbits with native form of weak toxin (WTX) from cobra Naja kaouthia venom efficiently interacted with WTX…”
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Aromatic substitutions in alpha-conotoxin ImI. Synthesis of iodinated photoactivatable derivative by Utkin, Y N, Zhmak, M N, Methfessel, C, Tsetlin, V I

“…Conotoxin ImI is a specific marker of alpha7 nicotinic acetylcholine receptors. To study the role of aromatic indole group of tryptophan 10 in biological…”
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Toxicity of cobra venom components to cockroach Gromphadorhina portentosa by Osipov, Alexey V, Starkov, Vladislav G, Utkin, Yuri N

“…The toxicity of the Thailand and Middle-Asian cobra venoms as well as of their isolated components (neurotoxins, cytotoxins, phospholipases and some others)…”
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Interaction of the P‐type cardiotoxin with phospholipid membranes by Dubovskii, Peter V., Lesovoy, Dmitry M., Dubinnyi, Maxim A., Utkin, Yuri N., Arseniev, Alexander S.

“…The cardiotoxin (cytotoxin II, or CTII) isolated from cobra snake (Naja oxiana) venom is a 60‐residue basic membrane‐active protein featuring three‐finger beta…”
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Relationship between the binding sites for an alpha-conotoxin and snake venom neurotoxins in the nicotinic acetylcholine receptor from Torpedo californica by Utkin, Y N, Kobayashi, Y, Hucho, F, Tsetlin, V I

“…Photoinduced cross-links between the iodinated Lys26-p-azidobenzoyl derivative of neurotoxin II from Naja naja oxiana cobra venom and nicotinic acetylcholine…”
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