Search Results - "UTE HAMANN"

Tissue-Specific Down-Regulation of the Long Non-Coding RNAs PCAT18 and LINC01133 in Gastric Cancer Development by Foroughi, Kobra, Amini, Mohammad, Atashi, Amir, Mahmoodzadeh, Habibollah, Hamann, Ute, Manoochehri, Mehdi

“…Gastric cancer (GC) is the fifth most common cancer and the third most frequent cause of cancer deaths worldwide. The high death rate associated with GC, and…”
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Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study by Rashid, Muhammad Usman, Muzaffar, Merium, Khan, Faiz Ali, Kabisch, Maria, Muhammad, Noor, Faiz, Sabeen, Loya, Asif, Hamann, Ute

“…Vitamin D is postulated to decrease the risk of breast cancer by inhibiting cell proliferation via the vitamin D receptor (VDR). Two common single nucleotide…”
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Native American ancestry and breast cancer risk in Colombian and Mexican women: ruling out potential confounding through ancestry-informative markers by Zollner, Linda, Torres, Diana, Briceno, Ignacio, Gilbert, Michael, Torres-Mejía, Gabriela, Dennis, Joe, Bolla, Manjeet K, Wang, Qin, Hamann, Ute, Lorenzo Bermejo, Justo

“…Background Latin American and Hispanic women are less likely to develop breast cancer (BC) than women of European descent. Observational studies have found an…”
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DNA methylation of the long intergenic noncoding RNA 299 gene in triple-negative breast cancer: results from a prospective study by Manoochehri, Mehdi, Jones, Michael, Tomczyk, Katarzyna, Fletcher, Olivia, Schoemaker, Minouk J., Swerdlow, Anthony J., Borhani, Nasim, Hamann, Ute

“…Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype associated with a high rate of recurrence and poor prognosis. Recently we…”
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Marginal Contribution of Pathogenic RAD51D Germline Variants to Pakistani Early-Onset and Familial Breast/Ovarian Cancer Patients by Muhammad, Noor, Afzal, Muhammad Sohail, Hamann, Ute, Rashid, Muhammad Usman

“…has been reported as a breast cancer (BC) and ovarian cancer (OC) predisposition gene, particularly among Caucasian populations. We studied the prevalence of…”
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Imputation of missing genotypes within LD-blocks relying on the basic coalescent and beyond: consideration of population growth and structure by Kabisch, Maria, Hamann, Ute, Lorenzo Bermejo, Justo

“…Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard…”
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Estrogen receptor alpha and nuclear factor Y coordinately regulate the transcription of the SUMO-conjugating UBC9 gene in MCF-7 breast cancer cells by Ying, Shibo, Dünnebier, Thomas, Si, Jing, Hamann, Ute

“…UBC9 encodes a protein that conjugates small ubiquitin-related modifier (SUMO) to target proteins thereby changing their functions. Recently, it was noted that…”
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Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients by Rashid, Muhammad Usman, Muhammad, Noor, Khan, Faiz Ali, Shehzad, Umara, Naeemi, Humaira, Malkani, Naila, Hamann, Ute

“…The RecQ Like Helicase (RECQL) gene has previously been shown to predispose to breast cancer mainly in European populations, in particular to estrogen receptor…”
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Spectrum and prevalence of BRCA1/2 germline mutations in Pakistani breast cancer patients: results from a large comprehensive study by Rashid, Muhammad Usman, Muhammad, Noor, Naeemi, Humaira, Khan, Faiz Ali, Hassan, Mariam, Faisal, Saima, Gull, Sidra, Amin, Asim, Loya, Asif, Hamann, Ute

“…Pathogenic germline mutations in and ( ) account for the majority of hereditary breast and/or ovarian cancers worldwide. To refine the spectrum of mutations…”
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High proportion of BRCA1/2 founder mutations in Hispanic breast/ovarian cancer families from Colombia by TORRES, Diana, MUHAMMAD USMAN RASHID, GIL, Fabian, UMANA, Angela, RAMELLI, Giancarlo, ROBLEDO, Jose Fernando, TAWIL, Mauricio, TORREGROSA, Lilian, BRICENO, Ignacio, HAMANN, Ute

“…In South America, a high proportion of the population is of Hispanic origin with an important representation in Colombia. Since nothing is known about the…”
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Night Work and Breast Cancer Estrogen Receptor Status-Results from the German GENICA Study by Rabstein, Sylvia, Harth, Volker, Pesch, Beate, Pallapies, Dirk, Lotz, Anne, Justenhoven, Christina, Baisch, Christian, Schiffermann, Markus, Haas, Susanne, Fischer, Hans-Peter, Heinze, Evelyn, Pierl, Christiane, Brauch, Hiltrud, Hamann, Ute, Ko, Yon, Brüning, Thomas

“…Objectives The potential mechanisms that link night-shift work with breast cancer have been extensively discussed. Exposure to light at night (LAN) depletes…”
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Night Work and Breast cancer-results from the German GENICA Study by Pesch, Beate, Harth, Volker, Rabstein, Sylvia, Baisch, Christian, Schiffermann, Markus, Pallapies, Dirk, Bonberg, Nadine, Heinze, Evelyn, Spickenheuer, Anne, Justenhoven, Christina, Brauch, Hiltrud, Hamann, Ute, Ko, Yon, Straif, Kurt, Brüning, Thomas

“…Objective Some epidemiological and animal data indicate that night work might increase the risk for breast cancer. We have investigated the risk in a German…”
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Correction to: Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients by Rashid, Muhammad Usman, Muhammad, Noor, Khan, Faiz Ali, Shehzad, Umara, Naeemi, Humaira, Malkani, Naila, Hamann, Ute

“…An amendment to this paper has been published and can be accessed via the original article…”
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Prevalence of PALB2 Germline Mutations in Early-onset and Familial Breast/Ovarian Cancer Patients from Pakistan by Rashid, Muhammad Usman, Khan, Faiz Ali, Muhammad, Noor, Loya, Asif, Hamann, Ute

“…Partner and localizer of BRCA2 (PALB2) is a breast cancer susceptibility gene that plays an important role in DNA repair. This is the first study assessing the…”
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Systematic pathway enrichment analysis of a genome-wide association study on breast cancer survival reveals an influence of genes involved in cell adhesion and calcium signaling on the patients' clinical outcome by Woltmann, Andrea, Chen, Bowang, Lascorz, Jesús, Johansson, Robert, Eyfjörd, Jorunn E, Hamann, Ute, Manjer, Jonas, Enquist-Olsson, Kerstin, Henriksson, Roger, Herms, Stefan, Hoffmann, Per, Hemminki, Kari, Lenner, Per, Försti, Asta

“…Genome-wide association studies (GWASs) may help to understand the effects of genetic polymorphisms on breast cancer (BC) progression and survival. However,…”
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ERCC2 Genotypes and a Corresponding Haplotype Are Linked with Breast Cancer Risk in a German Population by Justenhoven, Christina, Hamann, Ute, Pesch, Beate, Harth, Volker, Rabstein, Sylvia, Baisch, Christian, Vollmert, Caren, Illig, Thomas, Ko, Yon-Dschun, Brüning, Thomas, Brauch, Hiltrud

“…The polygenic concept of breast cancer susceptibility calls for the identification of genetic variants that contribute to breast cancer risk. Reduced DNA…”
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Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk by Ashton, Katie A, Proietto, Anthony, Otton, Geoffrey, Symonds, Ian, McEvoy, Mark, Attia, John, Gilbert, Michael, Hamann, Ute, Scott, Rodney J

“…Abstract Objectives : The incidence of endometrial cancer has recently increased substantially and studies have shown that altered levels of exogenous and…”
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Exploring the association between genetic variation in the SUMO isopeptidase gene USPL1 and breast cancer through integration of data from the population‐based GENICA study and external genetic databases by Bermejo, Justo Lorenzo, Kabisch, Maria, Dünnebier, Thomas, Schnaidt, Sven, Melchior, Frauke, Fischer, Hans‐Peter, Harth, Volker, Rabstein, Sylvia, Pesch, Beate, Brüning, Thomas, Justenhoven, Christina, Brauch, Hiltrud, Baisch, Christian, Ko, Yon‐Dschun, Hamann, Ute

“…Small ubiquitin‐like modifier (SUMO) proteins are covalently attached to target proteins to modify their function. SUMO conjugation participates in processes…”
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The RAD51 135 G>C Polymorphism Modifies Breast Cancer and Ovarian Cancer Risk in Polish BRCA1 Mutation Carriers by JAKUBOWSKA, Anna, GRONWALD, Jacek, MENKISZAK, Janusz, GORSKI, Bohdan, HUZARSKI, Tomasz, BYRSKI, Tomasz, EDLER, Lutz, LUBIFISKI, Jan, SCOTT, Rodney J, HAMANN, Ute

“…Breast and ovarian cancer penetrance in BRCA1 mutation carriers is estimated to be between 15% and 80% by age 70 years. At present, it is not possible to…”
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Expression of xenobiotic and steroid hormone metabolizing enzymes in human breast carcinomas by Haas, Susanne, Pierl, Christiane, Harth, Volker, Pesch, Beate, Rabstein, Sylvia, Brüning, Thomas, Ko, Yon, Hamann, Ute, Justenhoven, Christina, Brauch, Hiltrud, Fischer, Hans‐Peter

“…The potential to metabolize endogenous and exogenous substances may influence breast cancer development and tumor growth. Therefore, the authors investigated…”
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