Search Results - "USUI, Noriyoshi"

Possible roles of deep cortical neurons and oligodendrocytes in the neural basis of human sociality by Usui, Noriyoshi

“…Sociality is an instinctive property of organisms that live in relation to others and is a complex characteristic of higher order brain functions. However, the…”
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Neuroinflammation and Oxidative Stress in the Pathogenesis of Autism Spectrum Disorder by Usui, Noriyoshi, Kobayashi, Hikaru, Shimada, Shoichi

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by impairments in social communication, repetitive behaviors, restricted…”
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Prenatal Environment and Neurodevelopmental Disorders by Doi, Miyuki, Usui, Noriyoshi, Shimada, Shoichi

“…The internal and external environment of the mother during the developmental stages of the fetus affects the offspring's health. According to the developmental…”
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Evolution of DNA methylation in the human brain by Jeong, Hyeonsoo, Mendizabal, Isabel, Berto, Stefano, Chatterjee, Paramita, Layman, Thomas, Usui, Noriyoshi, Toriumi, Kazuya, Douglas, Connor, Singh, Devika, Huh, Iksoo, Preuss, Todd M., Konopka, Genevieve, Yi, Soojin V.

“…DNA methylation is a critical regulatory mechanism implicated in development, learning, memory, and disease in the human brain. Here we have elucidated DNA…”
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Prenatal Sex Hormone Exposure Is Associated with the Development of Autism Spectrum Disorder by Li, Mengwei, Usui, Noriyoshi, Shimada, Shoichi

“…Sexual differentiation is a major developmental process. Sex differences resulting from sexual differentiation have attracted the attention of researchers…”
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Cell type-specific epigenetic links to schizophrenia risk in the brain by Mendizabal, Isabel, Berto, Stefano, Usui, Noriyoshi, Toriumi, Kazuya, Chatterjee, Paramita, Douglas, Connor, Huh, Iksoo, Jeong, Hyeonsoo, Layman, Thomas, Tamminga, Carol A, Preuss, Todd M, Konopka, Genevieve, Yi, Soojin V

“…The importance of cell type-specific epigenetic variation of non-coding regions in neuropsychiatric disorders is increasingly appreciated, yet data from…”
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Evolution of the Human Brain Can Help Determine Pathophysiology of Neurodevelopmental Disorders by Irie, Koichiro, Doi, Miyuki, Usui, Noriyoshi, Shimada, Shoichi

“…The evolution of humans brought about a co-occurring evolution of the human brain, which is far larger and more complex than that of many other organisms. The…”
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Accelerated evolution of oligodendrocytes in the human brain by Berto, Stefano, Mendizabal, Isabel, Usui, Noriyoshi, Toriumi, Kazuya, Chatterjee, Paramita, Douglas, Connor, Tamminga, Carol A., Preuss, Todd M., Yi, Soojin V., Konopka, Genevieve

“…Recent discussions of human brain evolution have largely focused on increased neuron numbers and changes in their connectivity and expression. However, it is…”
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Genomic Strategies for Understanding the Pathophysiology of Autism Spectrum Disorder by Doi, Miyuki, Li, Mengwei, Usui, Noriyoshi, Shimada, Shoichi

“…Recent breakthroughs in sequencing technology and technological developments have made it easier to analyze the entire human genome than ever before. In…”
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ELAVL2-regulated transcriptional and splicing networks in human neurons link neurodevelopment and autism by Berto, Stefano, Usui, Noriyoshi, Konopka, Genevieve, Fogel, Brent L

“…The role of post-transcriptional gene regulation in human brain development and neurodevelopmental disorders remains mostly uncharacterized. ELAV-like…”
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Zbtb16 regulates social cognitive behaviors and neocortical development by Usui, Noriyoshi, Berto, Stefano, Konishi, Ami, Kondo, Makoto, Konopka, Genevieve, Matsuzaki, Hideo, Shimada, Shoichi

“…Zinc finger and BTB domain containing 16 (ZBTB16) play the roles in the neural progenitor cell proliferation and neuronal differentiation during development,…”
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Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment by Toriumi, Kazuya, Miyashita, Mitsuhiro, Suzuki, Kazuhiro, Yamasaki, Nao, Yasumura, Misako, Horiuchi, Yasue, Yoshikawa, Akane, Asakura, Mai, Usui, Noriyoshi, Itokawa, Masanari, Arai, Makoto

“…We have reported that a subpopulation of patients with schizophrenia have lower levels of vitamin B 6 (VB6) in peripheral blood than do healthy controls. In a…”
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SR 57227A, a serotonin type-3 receptor agonist, as a candidate analgesic agent targeting nociplastic pain by Nakamura, Yukiko, Sumi, Takuya, Mitani, Osamu, Okamoto, Takashi, Kubo, Erika, Masui, Kuniharu, Kondo, Makoto, Koyama, Yoshihisa, Usui, Noriyoshi, Shimada, Shoichi

“…Pain is influenced by various factors, such as fear, anxiety, and memory. We previously reported that pain-like behaviors in mice can be induced by…”
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Early Life Stress Alters Gene Expression and Cytoarchitecture in the Prefrontal Cortex Leading to Social Impairment and Increased Anxiety by Usui, Noriyoshi, Ono, Yuta, Aramaki, Ryoko, Berto, Stefano, Konopka, Genevieve, Matsuzaki, Hideo, Shimada, Shoichi

“…Early life stress (ELS), such as abuse, neglect, and maltreatment, exhibits a strong impact on the brain and mental development of children. However, it is not…”
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Foxp1 regulation of neonatal vocalizations via cortical development by Usui, Noriyoshi, Araujo, Daniel J, Kulkarni, Ashwinikumar, Co, Marissa, Ellegood, Jacob, Harper, Matthew, Toriumi, Kazuya, Lerch, Jason P, Konopka, Genevieve

“…The molecular mechanisms driving brain development at risk in autism spectrum disorders (ASDs) remain mostly unknown. Previous studies have implicated the…”
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Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects by Hanners, Natasha W., Eitson, Jennifer L., Usui, Noriyoshi, Richardson, R. Blake, Wexler, Eric M., Konopka, Genevieve, Schoggins, John W.

“…The recent Zika virus (ZIKV) outbreak in the Western hemisphere is associated with severe pathology in newborns, including microcephaly and brain damage. The…”
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Prenatal methamphetamine exposure causes dysfunction in glucose metabolism and low birthweight by Doi, Miyuki, Nakama, Nanako, Sumi, Takuya, Usui, Noriyoshi, Shimada, Shoichi

“…Methamphetamine (METH) is a psychostimulant drug that induces addiction. Previous epidemiological studies have demonstrated that maternal METH abuse during…”
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Sumoylation of FOXP2 Regulates Motor Function and Vocal Communication Through Purkinje Cell Development by Usui, Noriyoshi, Co, Marissa, Harper, Matthew, Rieger, Michael A, Dougherty, Joseph D, Konopka, Genevieve

“…Abstract Background Mutations in the gene encoding the transcription factor forkhead box P2 ( FOXP2 ) result in brain developmental abnormalities, including…”
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Characterization of Early Life Stress-Affected Gut Microbiota by Usui, Noriyoshi, Matsuzaki, Hideo, Shimada, Shoichi

“…Early life stress (ELS), such as neglect and maltreatment, exhibits a strong impact on the mental and brain development of children. However, it is not fully…”
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Length impairments of the axon initial segment in rodent models of attention-deficit hyperactivity disorder and autism spectrum disorder by Usui, Noriyoshi, Tian, Xiaoye, Harigai, Wakana, Togawa, Shogo, Utsunomiya, Ryo, Doi, Tomomi, Miyoshi, Ko, Shinoda, Koh, Tanaka, Junya, Shimada, Shoichi, Katayama, Taiichi, Yoshimura, Takeshi

“…The axon initial segment (AIS) is a structural neuronal compartment of the proximal axon that plays key roles in sodium channel clustering, action potential…”
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