Search Results - "USTAV, Mart"
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Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice
Published in eLife (27-08-2019)“…Secreted Wnt proteins regulate development and adult tissue homeostasis by binding and activating cell-surface Frizzled receptors and co-receptors including…”
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Dynamics of antibody response to BNT162b2 vaccine after six months: a longitudinal prospective study
Published in The Lancet regional health. Europe (01-11-2021)“…SARS-CoV-2 mRNA vaccines have proven high efficacy, however, limited data exists on the duration of immune responses and their relation to age and side…”
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3
Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay
Published in PLoS pathogens (01-02-2017)“…Human papillomaviruses (HPVs) are oncogenic viruses that cause numerous different cancers as well as benign lesions in the epithelia. To date, there is no…”
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4
Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates
Published in PLoS pathogens (02-08-2023)“…The COVID-19 pandemic represents a global challenge that has impacted and is expected to continue to impact the lives and health of people across the world for…”
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5
Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2
Published in Cell host & microbe (09-09-2020)“…Antibody-based interventions against SARS-CoV-2 could limit morbidity, mortality, and possibly transmission. An anticipated correlate of such countermeasures…”
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6
The Cell Cycle Timing of Human Papillomavirus DNA Replication
Published in PloS one (01-07-2015)“…Viruses manipulate the cell cycle of the host cell to optimize conditions for more efficient viral genome replication. One strategy utilized by DNA viruses is…”
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Engagement of the ATR-Dependent DNA Damage Response at the Human Papillomavirus 18 Replication Centers during the Initial Amplification
Published in Journal of Virology (01-01-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Anti-SARS-CoV-2 antibodies in a nasal spray efficiently block viral transmission between ferrets
Published in iScience (19-07-2024)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread in the population. We recently reported the production of bovine…”
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Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2
Published in Communications biology (12-04-2021)“…COVID-19 is a respiratory illness caused by a novel coronavirus called SARS-CoV-2. The viral spike (S) protein engages the human angiotensin-converting enzyme…”
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10
E2 protein is the major determinant of specificity at the human papillomavirus origin of replication
Published in PloS one (23-10-2019)“…The replication of human papillomavirus (HPV) genomes requires E1 and E2 proteins as the viral trans-factors and the replication origin, located in the URR, as…”
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Boosted production of antibodies that neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following messenger RNA vaccination - a case study
Published in International journal of infectious diseases (01-12-2023)“…•Messenger RNA vaccination boosted the production of serum anti-SARS-CoV-2 antibodies.•The antibodies neutralized strains of 19A, 20A, 20B, 20H, 21J, and 21K…”
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The transcription map of human papillomavirus type 18 during genome replication in U2OS cells
Published in PloS one (30-12-2014)“…The human osteosarcoma cell line U2OS is useful for studying genome replication of human papillomavirus (HPVs) subtypes that belong to different phylogenetic…”
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Bovine colostrum-derived antibodies against SARS-CoV-2 show great potential to serve as prophylactic agents
Published in PloS one (10-06-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to impose a serious burden on health systems globally. Despite worldwide vaccination,…”
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Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses
Published in PLoS pathogens (01-04-2009)“…In HPV-related cancers, the "high-risk" human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV…”
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Development of a Cellular Assay System To Study the Genome Replication of High- and Low-Risk Mucosal and Cutaneous Human Papillomaviruses
Published in Journal of Virology (01-04-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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16
Activity of CK2α protein kinase is required for efficient replication of some HPV types
Published in PLoS pathogens (01-05-2019)“…Inhibition of human papillomavirus (HPV) replication is a promising therapeutic approach for intervening with HPV-related pathologies. Primary targets for…”
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Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle
Published in PloS one (26-11-2019)“…The Sonic Hedgehog (Shh) signalling pathway plays multiple roles during embryonic development and under pathological conditions. Although the core components…”
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Electroporation as a vaccine delivery system and a natural adjuvant to intradermal administration of plasmid DNA in macaques
Published in Scientific reports (23-06-2017)“…In vivo electroporation (EP) is used to enhance the uptake of nucleic acids and its association with DNA vaccination greatly stimulates immune responses to…”
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Mapping of Betapapillomavirus Human Papillomavirus 5 Transcription and Characterization of Viral-Genome Replication Function
Published in Journal of Virology (01-01-2014)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis
Published in Nature communications (03-02-2024)“…Obesity, a global health challenge, is a major risk factor for multiple life-threatening diseases, including diabetes, fatty liver, and cancer. There is an…”
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