Search Results - "USTAV, Mart"

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    Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice by Tao, Yuyong, Mis, Monika, Blazer, Levi, Ustav, Jnr, Mart, Steinhart, Zachary, Chidiac, Rony, Kubarakos, Elli, O'Brien, Siobhan, Wang, Xiaomei, Jarvik, Nick, Patel, Nish, Adams, Jarrett, Moffat, Jason, Angers, Stephane, Sidhu, Sachdev S

    Published in eLife (27-08-2019)
    “…Secreted Wnt proteins regulate development and adult tissue homeostasis by binding and activating cell-surface Frizzled receptors and co-receptors including…”
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    Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay by Toots, Mart, Ustav, Jr, Mart, Männik, Andres, Mumm, Karl, Tämm, Kaido, Tamm, Tarmo, Ustav, Ene, Ustav, Mart

    Published in PLoS pathogens (01-02-2017)
    “…Human papillomaviruses (HPVs) are oncogenic viruses that cause numerous different cancers as well as benign lesions in the epithelia. To date, there is no…”
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    The Cell Cycle Timing of Human Papillomavirus DNA Replication by Reinson, Tormi, Henno, Liisi, Toots, Mart, Ustav, Jr, Mart, Ustav, Mart

    Published in PloS one (01-07-2015)
    “…Viruses manipulate the cell cycle of the host cell to optimize conditions for more efficient viral genome replication. One strategy utilized by DNA viruses is…”
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    Engagement of the ATR-Dependent DNA Damage Response at the Human Papillomavirus 18 Replication Centers during the Initial Amplification by Reinson, Tormi, Toots, Mart, Kadaja, Meelis, Pipitch, Regina, Allik, Mihkel, Ustav, Ene, Ustav, Mart

    Published in Journal of Virology (01-01-2013)
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    E2 protein is the major determinant of specificity at the human papillomavirus origin of replication by Laaneväli, Airiin, Ustav, Mart, Ustav, Ene, Piirsoo, Marko

    Published in PloS one (23-10-2019)
    “…The replication of human papillomavirus (HPV) genomes requires E1 and E2 proteins as the viral trans-factors and the replication origin, located in the URR, as…”
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    The transcription map of human papillomavirus type 18 during genome replication in U2OS cells by Toots, Mart, Männik, Andres, Kivi, Gaily, Ustav, Jr, Mart, Ustav, Ene, Ustav, Mart

    Published in PloS one (30-12-2014)
    “…The human osteosarcoma cell line U2OS is useful for studying genome replication of human papillomavirus (HPVs) subtypes that belong to different phylogenetic…”
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    Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses by Kadaja, Meelis, Isok-Paas, Helen, Laos, Triin, Ustav, Ene, Ustav, Mart

    Published in PLoS pathogens (01-04-2009)
    “…In HPV-related cancers, the "high-risk" human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV…”
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    Development of a Cellular Assay System To Study the Genome Replication of High- and Low-Risk Mucosal and Cutaneous Human Papillomaviruses by GEIMANEN, Jelizaveta, ISOK-PAAS, Helen, PIPITCH, Regina, SALK, Kristiina, LAOS, Triin, ORAV, Marit, REINSON, Tormi, USTAV, Mart, USTAV, Mart, USTAV, Ene

    Published in Journal of Virology (01-04-2011)
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    Activity of CK2α protein kinase is required for efficient replication of some HPV types by Piirsoo, Alla, Piirsoo, Marko, Kala, Martin, Sankovski, Eve, Lototskaja, Elina, Levin, Viktor, Salvi, Mauro, Ustav, Mart

    Published in PLoS pathogens (01-05-2019)
    “…Inhibition of human papillomavirus (HPV) replication is a promising therapeutic approach for intervening with HPV-related pathologies. Primary targets for…”
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    Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle by Piirsoo, Alla, Pink, Anne, Kasak, Lagle, Kala, Martin, Kasvandik, Sergo, Ustav, Mart, Piirsoo, Marko

    Published in PloS one (26-11-2019)
    “…The Sonic Hedgehog (Shh) signalling pathway plays multiple roles during embryonic development and under pathological conditions. Although the core components…”
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    Electroporation as a vaccine delivery system and a natural adjuvant to intradermal administration of plasmid DNA in macaques by Todorova, Biliana, Adam, Lucille, Culina, Slobodan, Boisgard, Raphaël, Martinon, Frédéric, Cosma, Antonio, Ustav, Mart, Kortulewski, Thierry, Le Grand, Roger, Chapon, Catherine

    Published in Scientific reports (23-06-2017)
    “…In vivo electroporation (EP) is used to enhance the uptake of nucleic acids and its association with DNA vaccination greatly stimulates immune responses to…”
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    Mapping of Betapapillomavirus Human Papillomavirus 5 Transcription and Characterization of Viral-Genome Replication Function by Sankovski, Eve, Männik, Andres, Geimanen, Jelizaveta, Ustav, Ene, Ustav, Mart

    Published in Journal of Virology (01-01-2014)
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    Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis by Guo, Xuanming, Asthana, Pallavi, Zhai, Lixiang, Cheng, Ka Wing, Gurung, Susma, Huang, Jiangang, Wu, Jiayan, Zhang, Yijing, Mahato, Arun Kumar, Saarma, Mart, Ustav, Mart, Kwan, Hiu Yee, Lyu, Aiping, Chan, Kui Ming, Xu, Pingyi, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier

    Published in Nature communications (03-02-2024)
    “…Obesity, a global health challenge, is a major risk factor for multiple life-threatening diseases, including diabetes, fatty liver, and cancer. There is an…”
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