Search Results - "URFER, Roman"

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  1. 1

    Sigma-1 receptor chaperones regulate the secretion of brain-derived neurotrophic factor by Fujimoto, Michiko, Hayashi, Teruo, Urfer, Roman, Mita, Shiro, Su, Tsung-Ping

    Published in Synapse (New York, N.Y.) (01-07-2012)
    “…The sigma‐1 receptor (Sig‐1R) is a novel endoplasmic reticulum (ER) molecular chaperone that regulates protein folding and degradation. The Sig‐1R activation…”
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  2. 2

    Phase II Trial of the Sigma-1 Receptor Agonist Cutamesine (SA4503) for Recovery Enhancement After Acute Ischemic Stroke by URFER, Roman, MOEBIUS, Hans J, SKOLOUDIK, David, SANTAMARINA, Estevo, SATO, Wakao, MITA, Shiro, MUIR, Keith W

    Published in Stroke (1970) (01-11-2014)
    “…The σ-1 receptor (Sig-1R) agonist cutamesine (SA4503) enhanced functional recovery after experimental stroke with a treatment initiation window of 48 hours and…”
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  3. 3

    The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke by RUSCHER, Karsten, SHAMLOO, Mehrdad, JOHANSSON, Barbro B, NIKOLICH, Karoly, WIELOCH, Tadeusz, RICKHAG, Mattias, LADUNGA, Istvan, SORIANO, Liza, GISSELSSON, Lennart, TORESSON, Hakan, RUSLIM-LITRUS, Lily, OKSENBERG, Donna, URFER, Roman

    Published in Brain (London, England : 1878) (01-03-2011)
    “…Stroke leads to brain damage with subsequent slow and incomplete recovery of lost brain functions. Enriched housing of stroke-injured rats provides multi-modal…”
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  4. 4

    Death-associated Protein Kinase Is Activated by Dephosphorylation in Response to Cerebral Ischemia by Shamloo, Mehrdad, Soriano, Liza, Wieloch, Tadeusz, Nikolich, Karoly, Urfer, Roman, Oksenberg, Donna

    Published in The Journal of biological chemistry (23-12-2005)
    “…Death-associated protein kinase (DAPK) is a calcium calmodulin-regulated serine/threonine protein kinase involved in ischemic neuronal death. In situ…”
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  5. 5

    GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion by SHASHIDHAR, Sumana, LORENTE, Gustavo, NAGAVARAPU, Usha, NELSON, April, KUO, Jane, CUMMINS, Jeramiah, NIKOLICH, Karoly, URFER, Roman, FOEHR, Erik D

    Published in Oncogene (03-03-2005)
    “…GPR56 (also known as TM7XN1) is a newly discovered orphan G-protein-coupled receptor (GPCR) of the secretin family that has a role in the development of neural…”
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  6. 6

    Regulation of NMDA receptor trafficking and function by striatal-enriched tyrosine phosphatase (STEP) by Braithwaite, Steven P., Adkisson, Michael, Leung, John, Nava, Adrian, Masterson, Brett, Urfer, Roman, Oksenberg, Donna, Nikolich, Karoly

    Published in The European journal of neuroscience (01-06-2006)
    “…Regulation of N‐methyl‐d‐aspartate (NMDA) receptors is critical for the normal functioning of the central nervous system. There must be precise mechanisms to…”
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  7. 7

    A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke by Beraki, Simret, Litrus, Lily, Soriano, Liza, Monbureau, Marie, To, Lillian K, Braithwaite, Steven P, Nikolich, Karoly, Urfer, Roman, Oksenberg, Donna, Shamloo, Mehrdad

    Published in PloS one (18-07-2013)
    “…With the availability and ease of small molecule production and design continuing to improve, robust, high-throughput methods for screening are increasingly…”
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  8. 8

    Npas4, a novel helix-loop-helix PAS domain protein, is regulated in response to cerebral ischemia by Shamloo, Mehrdad, Soriano, Liza, Von Schack, David, Rickhag, Mattias, Chin, Daniel J., Gonzalez-Zulueta, Mirella, Gido, Gunilla, Urfer, Roman, Wieloch, Tadeusz, Nikolich, Karoly

    Published in The European journal of neuroscience (01-11-2006)
    “…Basic helix–loop–helix PAS domain proteins form a growing family of transcription factors. These proteins are involved in the process of adaptation to cellular…”
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  9. 9
  10. 10

    Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia by Braithwaite, Steven P., Xu, Jian, Leung, John, Urfer, Roman, Nikolich, Karoly, Oksenberg, Donna, Lombroso, Paul J., Shamloo, Mehrdad

    Published in The European journal of neuroscience (01-05-2008)
    “…Striatal enriched protein tyrosine phosphatase (STEP) acts in the central nervous system to dephosphorylate a number of important proteins involved in synaptic…”
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  11. 11

    The Viral CC Chemokine-binding Protein vCCI Inhibits Monocyte Chemoattractant Protein-1 Activity by Masking Its CCR2B-binding Site by Beck, C G, Studer, C, Zuber, J F, Demange, B J, Manning, U, Urfer, R

    Published in The Journal of biological chemistry (16-11-2001)
    “…Monocyte chemoattractant protein-1 (MCP-1) is a chemotactic cytokine mainly acting on monocytes and T cells that elicits its biological effects by interacting…”
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  12. 12

    A high-throughput turbidometric assay for screening inhibitors of protein disulfide isomerase activity by Smith, Anthony M, Chan, John, Oksenberg, Donna, Urfer, Roman, Wexler, David S, Ow, Arnie, Gao, Liping, McAlorum, Alanna, Huang, Shu-Gui

    Published in Journal of biomolecular screening (01-10-2004)
    “…Protein disulfide isomerase (PDI) plays a key role in protein folding by catalyzing rearrangements of disulfide bonds in substrate proteins following their…”
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  13. 13

    High Resolution Mapping of the Binding Site of TrkA for Nerve Growth Factor and TrkC for Neurotrophin-3 on the Second Immunoglobulin-like Domain of the Trk Receptors by Urfer, Roman, Tsoulfas, Pantelis, O'Connell, Lori, Hongo, Jo-Anne, Zhao, Wei, Presta, Leonard G.

    Published in The Journal of biological chemistry (06-03-1998)
    “…Neurotrophic factors are important for survival and maintenance of neurons during developmental and adult stages of the vertebrate nervous system. The…”
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  14. 14

    Identification of a Nuclear Respiratory Factor 1 Recognition Motif in the Apolipoprotein E Variant APOE4 linked to Alzheimer’s Disease by Urfer-Buchwalder, Anne, Urfer, Roman

    Published in Scientific reports (17-01-2017)
    “…Alzheimer’s disease affects tens of millions of people worldwide and its prevalence continues to rise. It is caused by a combination of a subject’s heredity,…”
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  15. 15

    Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2 by RAM, Rosalyn, LORENTE, Gustavo, NIKOLICH, Karoly, URFER, Roman, FOEHR, Erik, NAGAVARAPU, Usha

    Published in Journal of neuro-oncology (01-02-2006)
    “…Invasion of glioma cells involves the attachment of invading tumor cells to extracellular matrix (ECM), disruption of ECM components, and subsequent cell…”
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    Targeting of the receptor protein tyrosine phosphatase β with a monoclonal antibody delays tumor growth in a glioblastoma model by FOEHR, Erik D, LORENTE, Gustavo, KUO, Jane, RAM, Rosie, N IKOLICH, Karoly, URFER, Roman

    Published in Cancer research (Chicago, Ill.) (15-02-2006)
    “…The receptor protein tyrosine phosphatase beta (RPTPbeta) is a functional biomarker for several solid tumor types. RPTPbeta expression is largely restricted to…”
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  18. 18

    FAS associated phosphatase (FAP-1) blocks apoptosis of astrocytomas through dephosphorylation of FAS by FOEHR, Erik D, LORENTE, Gustavo, VINCENT, Valerie, NIKOLICH, Karoly, URFER, Roman

    Published in Journal of neuro-oncology (01-09-2005)
    “…Astrocytomas are the most common primary tumor of the adult human central nervous system. Despite efforts to develop more effective clinical treatment…”
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  19. 19

    The importance of surface loops for stabilizing an eightfold βα barrel protein by Urfer, Roman, Kirschner, Kasper

    Published in Protein science (01-01-1992)
    “…An important step in understanding how a protein folds is to determine those regions of the sequence that are critical to both its stability and its folding…”
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  20. 20

    A Pharmacological Screening Approach for Discovery of Neuroprotective Compounds in Ischemic Stroke. e69233 by Beraki, Simret, Litrus, Lily, Soriano, Liza, Monbureau, Marie, To, Lillian K, Braithwaite, Steven P, Nikolich, Karoly, Urfer, Roman, Oksenberg, Donna, Shamloo, Mehrdad

    Published in PloS one (01-07-2013)
    “…With the availability and ease of small molecule production and design continuing to improve, robust, high-throughput methods for screening are increasingly…”
    Get full text
    Journal Article