Search Results - "URBÁN, LÁSZLÓ"
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The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology
Published in European journal of pharmacology (01-10-2004)“…The cloning of the vanilloid receptor 1 opened a floodgate for discoveries regarding the function of this complex molecule. It has been found that, in addition…”
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Revising Incidence and Mortality of Lung Cancer in Central Europe: An Epidemiology Review From Hungary
Published in Frontiers in oncology (23-10-2019)“…Objective: While Hungary is often reported to have the highest incidence and mortality rates of lung cancer, until 2018 no nationwide epidemiology study was…”
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Lung Cancer in Hungary
Published in Journal of thoracic oncology (01-05-2020)Get more information
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Major Clinical Response to Afatinib Monotherapy in Lung Adenocarcinoma Harboring EGFR Exon 20 Insertion Mutation
Published in Clinical lung cancer (01-01-2021)Get full text
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Age and Gender Specific Lung Cancer Incidence and Mortality in Hungary: Trends from 2011 Through 2016
Published in Pathology oncology research (30-04-2021)“…No assessment was conducted describing the age and gender specific epidemiology of lung cancer (LC) prior to 2018 in Hungary, thus the objective of this study…”
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Improvement in Lung Cancer Survival: 6-Year Trends of Overall Survival at Hungarian Patients Diagnosed in 2011-2016
Published in Pathology oncology research (30-04-2021)“…Lung cancer is one of the most common cancers worldwide and its survival is still poor. The objective of our study was to estimate long-term survival of…”
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Increase in the Length of Lung Cancer Patient Pathway Before First-Line Therapy: A 6-Year Nationwide Analysis From Hungary
Published in Pathology oncology research (23-12-2021)“…This study aimed to examine the characteristics of the lung cancer (LC) patient pathway in Hungary during a 6-years period. This nationwide, retrospective…”
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Significant Regional Differences in Lung Cancer Incidence in Hungary: Epidemiological Study Between 2011 and 2016
Published in Pathology oncology research (14-09-2021)“…Hungary has one of the highest incidences and mortality rates of lung cancer (LC), therefore the objective of this study was to analyse and compare LC…”
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The effect of grassland management on diversity and composition of ground-dwelling spider assemblages in the Mátra Landscape Protection Area of Hungary
Published in Biológia (01-06-2017)“…The main objective of this paper is to report the effect of shrub removal and mowing on the diversity and composition of ground-dwelling spider assemblages in…”
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How grassland management methods affect spider diversity
Published in Acta Universitatis Sapientiae. Agriculture and environment (01-12-2019)“…The main objective of this paper is to report the effect of shrub removal, mowing, and grazing as grassland management methods on spider diversity. Sampling…”
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Efficacy of Incremental Next-Generation ALK Inhibitor Treatment in Oncogene-Addicted, ALK-Positive, TP53-Mutant NSCLC
Published in Journal of personalized medicine (01-09-2020)“…Background: The anaplastic lymphoma kinase (ALK) gene fusion rearrangement is a potent oncogene, accounting for 2–7% of lung adenocarcinomas, with higher…”
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Inflammatory Breast Cancer—Comparing the Effectivity of Preoperative Docetaxel-Epirubicine Protocol to Conventional Antracycline-Containing Chemotherapy to Achieve Clinical Benefit and Complete Pathological Response
Published in Pathology oncology research (01-09-2011)“…Our retrospective analysis compared the effectiveness of conventional antracycline-containing protocols (A+) and docetaxel/epirubicine (TE) as primary systemic…”
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Detection of a rare oligo(A) repeat tract mutation (8As → 7As) in the sequence encoding the La/SS-B autoantigen
Published in Analytical biochemistry (01-11-2007)“…Several diseases are characterized by the presence of point mutations, which are amenable to molecular detection using a number of methods such as PCR…”
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On the role of aging in the etiology of autoimmunity
Published in Gerontology (Basel) (01-05-2002)“…Several types of diseases, among others autoimmune illnesses, could be coupled with the general processes of aging. The two-edged sword of immune defense is…”
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TRPV4: Molecular Conductor of a Diverse Orchestra
Published in Physiological reviews (01-07-2016)“…Transient receptor potential vanilloid type 4 (TRPV4) is a calcium-permeable nonselective cation channel, originally described in 2000 by research teams led by…”
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HUNCHEST-II contributes to a shift to earlier-stage lung cancer detection: final results of a nationwide screening program
Published in European radiology (01-05-2024)“…Objectives The introduction of low-dose CT (LDCT) altered the landscape of lung cancer (LC) screening and contributed to the reduction of mortality rates…”
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Cobalt accumulation in neurons expressing ionotropic excitatory amino acid receptors in young rat spinal cord: morphology and distribution
Published in Journal of comparative neurology (1911) (15-06-1994)“…Excitatory amino acids (EAA) acting on N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and kainate receptors play…”
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Large-scale prediction and testing of drug activity on side-effect targets
Published in Nature (London) (21-06-2012)“…Discovering the unintended ‘off-targets’ that predict adverse drug reactions is daunting by empirical methods alone. Drugs can act on several protein targets,…”
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Abstract CT238: Associations of ctDNA levels during neoadjuvant treatment with pathological response in patients with resectable NSCLC from the phase 3 AEGEAN trial
Published in Cancer research (Chicago, Ill.) (05-04-2024)“…Abstract Background: In AEGEAN, perioperative durvalumab (D) + neoadjuvant (neoadj) chemotherapy (CT) significantly improved pathological complete response…”
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A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs
Published in Nature communications (19-07-2023)“…In vitro secondary pharmacology assays are an important tool for predicting clinical adverse drug reactions (ADRs) of investigational drugs. We created the…”
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