Search Results - "URANO, T."

Regulation of plasminogen activation on cell surfaces and fibrin by Urano, T., Castellino, F. J., Suzuki, Y.

“…Summary The fibrinolytic system dissolves fibrin and maintains vascular patency. Recent advances in imaging analyses allowed visualization of the…”
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Androgen induces G3BP2 and SUMO-mediated p53 nuclear export in prostate cancer by Ashikari, D, Takayama, K, Tanaka, T, Suzuki, Y, Obinata, D, Fujimura, T, Urano, T, Takahashi, S, Inoue, S

“…The androgen receptor (AR) has a central role in prostate cancer progression, particularly treatment-resistance disease including castration-resistant prostate…”
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Targeting Oct1 genomic function inhibits androgen receptor signaling and castration-resistant prostate cancer growth by Obinata, D, Takayama, K, Fujiwara, K, Suzuki, T, Tsutsumi, S, Fukuda, N, Nagase, H, Fujimura, T, Urano, T, Homma, Y, Aburatani, H, Takahashi, S, Inoue, S

“…Androgen receptor (AR) functions as a ligand-dependent transcription factor to regulate its downstream signaling for prostate cancer progression. AR complex…”
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Fruit and Vegetable Consumption and Incident Frailty in Older Adults: A Systematic Review and Meta-Analysis by Kojima, G, Taniguchi, Y, Urano, T

“…There is limited evidence regarding associations between fruit and vegetable consumption and incident frailty risk among older people. The objective of this…”
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Integration of cap analysis of gene expression and chromatin immunoprecipitation analysis on array reveals genome-wide androgen receptor signaling in prostate cancer cells by Takayama, K, Tsutsumi, S, Katayama, S, Okayama, T, Horie-Inoue, K, Ikeda, K, Urano, T, Kawazu, C, Hasegawa, A, Ikeo, K, Gojyobori, T, Ouchi, Y, Hayashizaki, Y, Aburatani, H, Inoue, S

“…The androgen receptor (AR) is a critical transcriptional factor that contributes to the development and the progression of prostate cancer (PCa) by regulating…”
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The effects of nicotine administration on the pathophysiology of rat aortic wall by Kugo, H, Zaima, N, Tanaka, H, Urano, T, Unno, N, Moriyama, T

“…Abdominal aortic aneurysm (AAA) is the progressive dilation of the abdominal aorta. Nicotine is reported to be associated with the development and rupture of…”
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Life‐threatening hemorrhage and prolonged wound healing are remarkable phenotypes manifested by complete plasminogen activator inhibitor‐1 deficiency in humans by IWAKI, T., TANAKA, A., MIYAWAKI, Y., SUZUKI, A., KOBAYASHI, T., TAKAMATSU, J., MATSUSHITA, T., UMEMURA, K., URANO, T., KOJIMA, T., TERAO, T., KANAYAMA, N.

“…Background: Plasminogen activator inhibitor‐1 (PAI‐1) is the primary physiological regulator of urokinase plasminogen activator (uPA) and tissue plasminogen…”
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Net ecosystem carbon dioxide exchange over grazed steppe in central Mongolia by Li, S.G, Asanuma, J, Eugster, W, Kotani, A, Liu, J.J, Urano, T, Oikawa, T, Davaa, G, Oyunbaatar, D, Sugita, M

“…This paper presents results of 1 year (from March 25, 2003 to March 24, 2004, 366 days) of continuous measurements of net ecosystem CO2 exchange (NEE) above a…”
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miR-148a is an androgen-responsive microRNA that promotes LNCaP prostate cell growth by repressing its target CAND1 expression by Murata, T, Takayama, K, Katayama, S, Urano, T, Horie-Inoue, K, Ikeda, K, Takahashi, S, Kawazu, C, Hasegawa, A, Ouchi, Y, Homma, Y, Hayashizaki, Y, Inoue, S

“…Recent advances in cancer biology reveal that microRNAs (miRNAs) are involved in the regulation of cancer-related genes, or they function as tumor suppressors…”
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Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies by OHASHI, S, SAKASHITA, G, BAN, R, NAGASAWA, M, MATSUZAKI, H, MURATA, Y, TANIGUCHI, H, SHIMA, H, FURUKAWA, K, URANO, T

“…Mammalian Aurora-A is related to a serine/threonine protein kinase that was originally identified by its close homology with Saccharomyces cerevisiae Ipl1p and…”
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Terf/TRIM17 stimulates degradation of kinetochore protein ZWINT and regulates cell proliferation by Endo, Hiroshi, Ikeda, Kazuhiro, Urano, Tomohiko, Horie-Inoue, Kuniko, Inoue, Satoshi

“…Terf/TRIM17 is a tripartite motif protein that has been originally isolated from testis. Terf has been characterized to exhibit an E3 ubiquitin ligase activity…”
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Identification of novel androgen response genes in prostate cancer cells by coupling chromatin immunoprecipitation and genomic microarray analysis by TAKAYAMA, K, KANESHIRO, K, INOUE, S, TSUTSUMI, S, HORIE-INOUE, K, IKEDA, K, URANO, T, IJICHI, N, OUCHI, Y, SHIRAHIGE, K, ABURATAN, H

“…The androgen receptor (AR) plays a key role as a transcriptional factor in prostate development and carcinogenesis. Identification of androgen-regulated genes…”
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Undesirable effects of citrus juice on the pharmacokinetics of drugs : Focus on recent studies by SAITO, Mitsuo, HIRATA-KOIZUMI, Mutsuko, MATSUMOTO, Mariko, URANO, Tsutomu, HASEGAWA, Ryuichi

“…It is well known that intake of grapefruit juice affects the pharmacokinetics of various kinds of drugs. It has been reported that other citrus juices also…”
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Fundamental study of small interfering RNAs for ganglioside GD3 synthase gene as a therapeutic target of lung cancers by KO, K, FURUKAWA, K, TAKAHASHI, T, URANO, T, SANAI, Y, NAGINO, M, NIMURA, Y, FURUKAWA, K

“…Gangliosides GD3 and GD2 are specifically expressed in neuro-ectoderm-derived tumors, and are considered to play roles in the malignant properties of those…”
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Estrogen receptor alpha knockout mice display osteoarthritis-like phenotype by Azuma, K, Ikeda, K, Urano, T, Ouchi, Y, Inoue, S

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Participation of elderly patients in registration trials for oncology drug applications in Japan by Yonemori, K., Hirakawa, A., Komiyama, N., Kouno, T., Ando, M., Fujiwara, Y., Urano, T., Akagawa, H., Maruyama, H., Toyoshima, S.

“…Background: The objective of this study was to evaluate the age-based enrolment of cancer patients into registration trials of new drug applications or…”
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Ral‐GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation by Urano, T., Emkey, R., Feig, L. A.

“…Ral proteins (RalA and RalB) comprise a distinct family of Ras‐related GTPases (Feig and Emkey, 1993). Recently, Ral‐GDS, the exchange factor that activates…”
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1304 POSTER Can We Detect Any Ethnic Differences in Toxicity in Early Phase Clinical Trials for Anticancer Drugs? by Oqura, T, Morita, S, Yonemori, K, Nonaka, T, Urano, T

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Surface structure analysis of metal adsorbed Si(1 1 1) surfaces by Patterson function with LEED I– V curves by Kuzushita, T., Murata, A., Yamamoto, A., Urano, T.

“…Wu and Tong proposed the calculation method of Patterson function obtained directly from the LEED I– V curves which shows the relative position of surface…”
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Rapid, specific and active site-catalyzed effect of tissue-plasminogen activator on hippocampus-dependent learning in mice by Pawlak, R, Nagai, N, Urano, T, Napiorkowska-Pawlak, D, Ihara, H, Takada, Y, Collen, D, Takada, A

“…In the present study we trained tissue-plasminogen activator (tPA)-knockout (tPA −/−) and wild-type (tPA +/+) male mice in step-down inhibitory avoidance…”
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