Search Results - "UPADHYAY, Dilip J"

Next-Generation Molecular Diagnostics Development by CRISPR/Cas Tool: Rapid Detection and Surveillance of Viral Disease Outbreaks by Srivastava, Sonal, Upadhyay, Dilip J, Srivastava, Ashish

“…Virus disease spreads effortlessly mechanically or through minute insect vectors that are extremely challenging to avoid. Emergence and reemergence of new…”
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Cissampelos pareira Linn: Natural Source of Potent Antiviral Activity against All Four Dengue Virus Serotypes by Sood, Ruchi, Raut, Rajendra, Tyagi, Poornima, Pareek, Pawan Kumar, Barman, Tarani Kanta, Singhal, Smita, Shirumalla, Raj Kumar, Kanoje, Vijay, Subbarayan, Ramesh, Rajerethinam, Ravisankar, Sharma, Navin, Kanaujia, Anil, Shukla, Gyanesh, Gupta, Y K, Katiyar, Chandra K, Bhatnagar, Pradip K, Upadhyay, Dilip J, Swaminathan, Sathyamangalam, Khanna, Navin

“…Dengue, a mosquito-borne viral disease, poses a significant global public health risk. In tropical countries such as India where periodic dengue outbreaks can…”
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Azithromycin Exhibits Activity Against Pseudomonas aeruginosa in Chronic Rat Lung Infection Model by Kumar, Manoj, Rao, Madhvi, Mathur, Tarun, Barman, Tarani Kanta, Joshi, Vattan, Chaira, Tridib, Singhal, Smita, Pandya, Manisha, Al Khodor, Souhaila, Upadhyay, Dilip J, Masuda, Nobuhisa

“…forms biofilms in the lungs of chronically infected cystic fibrosis patients, which are tolerant to both the treatment of antibiotics and the host immune…”
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Emergence and Molecular Characterization of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates from the Delhi Region in India by KHANNA, Alka, SAMUEL RAJ, V, TARAI, Bansidhar, SOOD, Ruchi, PAREEK, Pawan Kumar, UPADHYAY, Dilip J, SHARMA, Pawan, RATTAN, Ashok, SINGH SAINI, Kulvinder, SINGH, Harpal

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Mode of Action of Ranbezolid against Staphylococci and Structural Modeling Studies of Its Interaction with Ribosomes by KALIA, Vandana, MIGLANI, Rajni, RAI, V. Samuel, PURNAPATRE, Kedar P, MATHUR, Tarun, SINGHAL, Smita, KHAN, Seema, VOLETI, Sreedhara R, UPADHYAY, Dilip J, KULVINDER SINGH SAINI, RATTAN, Ashok

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In Vitro and In Vivo Activities of the Novel Ketolide RBx 14255 against Clostridium difficile by KUMAR, Manoj, MATHUR, Tarun, VAISHNAVI, Chetana, CHAKRABARTI, Anjan, DAS, Biswajit, BHATNAGAR, Pradip K, BARMAN, Tarani K, RAMKUMAR, G, BHATI, Ashish, SHUKLA, Gunjan, KALIA, Vandana, PANDA, Manisha, RAJ, V. Samuel, UPADHYAY, Dilip J

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Ciprofloxacin-resistant Neisseria meningitidis, Delhi, India by Singhal, Smita, Purnapatre, Kedar P, Kalia, Vandana, Dube, Smita, Nair, Deepti, Deb, Monorama, Aggarwal, Pushpa, Gupta, Sunil, Upadhyay, Dilip J, Rattan, Ashok, Raj, V Samuel

“…Decreased susceptibility of Neisseria meningitidis isolates to ciprofloxacin emerged from an outbreak in Delhi, India. Results of antimicrobial susceptibility…”
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In Vitro and In Vivo Activities of DS86760016, a Novel Leucyl-tRNA Synthetase Inhibitor for Gram-Negative Pathogens by Purnapatre, Kedar P, Rao, Madhvi, Pandya, Manisha, Khanna, Alka, Chaira, Tridib, Bambal, Ramesh, Upadhyay, Dilip J, Masuda, Nobuhisa

“…The emergence of multidrug-resistant (MDR) Gram-negative bacilli is a major concern in the treatment of nosocomial infections. Antibacterial agents with novel…”
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Novel azoles with potent antileishmanial activity by Mathur, Tarun, Kumar, Manoj, Barman, Tarani K, Raj, V Samuel, Upadhyay, Dilip J, Verma, Ashwani K

“…To investigate the antileishmanial activity of novel azole compounds against , which causes deadly visceral leishmaniasis disease. A focused azole-based…”
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DS86760016, a Leucyl-tRNA Synthetase Inhibitor with Activity against Pseudomonas aeruginosa by Kumar, Manoj, Rao, Madhvi, Purnapatre, Kedar P, Barman, Tarani Kanta, Joshi, Vattan, Kashyap, Amuliya, Chaira, Tridib, Bambal, Ramesh B, Pandya, Manisha, Khodor, Souhaila Al, Upadhyay, Dilip J, Masuda, Nobuhisa

“…DS86760016 is a new leucyl-tRNA-synthetase inhibitor at the preclinical development stage. DS86760016 showed potent activity against extended-spectrum…”
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Effect of DS-2969b, a novel GyrB inhibitor, on rat and monkey intestinal microbiota by Kumar, Manoj, Mathur, Tarun, Joshi, Vattan, Upadhyay, Dilip J., Inoue, Shin-ichi, Masuda, Nobuhisa

“…DS-2969b, a novel GyrB inhibitor, transiently and reversibly altered the counts of limited intestinal microbiota at around 10 μg/g of faecal levels in rats and…”
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Novel fluorobenzothiazole as a dual inhibitor of gyrase B and topoisomerase IV against Gram-positive pathogens by Barman, Tarani K, Kumar, Manoj, Chaira, Tridib, Singhal, Smita, Mathur, Tarun, Kalia, Vandana, Gangadharan, Ramkumar, Rao, Madhvi, Pandya, Manisha, Bhateja, Pragya, Sood, Ruchi, Upadhyay, Dilip J, Varughese, Shibu, Yadav, Ajay, Sharma, Lalima, Ramadass, Venkataramanan, Kumar, Naresh, Sattigeri, Jitendra, Bhatnagar, Pradip K, Raj, V Samuel

“…The development of a novel inhibitor targeting gyrase B and topoisomerase IV offers an opportunity to combat multidrug resistance. We investigated the activity…”
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Potential of the fluoroketolide RBx 14255 against Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae in an experimental murine meningitis model by Barman, Tarani Kanta, Kumar, Manoj, Chaira, Tridib, Gangadharan, Ramkumar, Singhal, Smita, Rao, Madhvi, Mathur, Tarun, Bhateja, Pragya, Pandya, Manisha, Ramadass, Venkataramanan, Chakrabarti, Anjan, Das, Biswajit, Upadhyay, Dilip J, Raj, V Samuel

“…Abstract Background RBx 14255 is a fluoroketolide in pre-clinical evaluation with potent activity against MDR Gram-positive pathogens. Objectives To…”
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In Vitro and In Vivo Activities of a Bi-Aryl Oxazolidinone, RBx 11760, against Gram-Positive Bacteria by Barman, Tarani Kanta, Kumar, Manoj, Mathur, Tarun, Chaira, Tridib, Ramkumar, G, Kalia, Vandana, Rao, Madhvi, Pandya, Manisha, Yadav, Ajay Singh, Das, Biswajit, Upadhyay, Dilip J, Hamidullah, Konwar, Rituraj, Raj, V Samuel, Singh, Harpal

“…RBx 11760, a bi-aryl oxazolidinone, was investigated for antibacterial activity against Gram-positive bacteria. The MIC s of RBx 11760 and linezolid against…”
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Synthesis and evaluation of thiomannosides, potent and orally active FimH inhibitors by Sattigeri, Jitendra A., Garg, Malvika, Bhateja, Pragya, Soni, Ajay, Rauf, Abdul Rehman Abdul, Gupta, Mahendrakumar, Deshmukh, Mahesh S., Jain, Tarun, Alekar, Nidhi, Barman, Tarani Kanta, Jha, Paras, Chaira, Tridib, Bambal, Ramesh B., Upadhyay, Dilip J., Nishi, Takahide

“…[Display omitted] •SARs of thiomannoside derivatives as FimH inhibitor.•FimH inhibitory activity and potential to inhibit biofilm formation.•Prophylactic…”
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Utilization of Bombyx mori larvae as a surrogate animal model for evaluation of the anti-infective potential of oxazolidinones by Barman, Tarani Kanta, Arora, Priya, Rao, Madhvi, Bhadauriya, Tripti, Upadhyay, Dilip J

“…Abstract Silkworm ( Bombyx mori ) larvae were investigated as an alternative animal model for the efficacy testing of novel oxazolidinones. The minimal lethal…”
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In vivo efficacy and pharmacokinetics of bi-aryl oxazolidinone RBx 11760 loaded polylactic acid–polyethylene glycol nanoparticles in mouse hematogenous bronchopneumonia and rat groin abscess caused by Staphylococcus aureus by Barman, Tarani Kanta, Kumar, Manoj, Chaira, Tridib, Dalela, Manu, Gupta, Dikshi, Jha, Paras Kumar, Yadav, Ajay Singh, Upadhyay, Dilip J., Raj, V Samuel, Singh, Harpal

“…RBx 11760 is a bi-aryl oxazolidinone antibacterial agent active against Staphylococcus aureus but has poor solubility. Here we have encapsulated RBx 11760 in…”
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Culturable bioactive actinomycetes from the Great Indian Thar Desert by Tiwari, Kavita, Upadhyay, Dilip J, Mösker, Eva, Süssmuth, Roderich, Gupta, Rajinder K

“…The present study was attempted to determine the antimicrobial potential of actinomycetes from the Great Indian Thar Desert. A total of 100 different…”
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Anti-anaerobic potential of ranbezolid: insight into its mechanism of action against Bacteroides fragilis by Mathur, Tarun, Kalia, Vandana, Barman, Tarani Kanta, Singhal, Smita, Khan, Seema, Upadhyay, Dilip J, Rattan, Ashok, Raj, V. Samuel

“…Abstract This study reports the anti-anaerobic properties of ranbezolid, a new investigational oxazolidinone. A time–kill kinetics study against anaerobes…”
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A Novel Ketolide, RBx 14255, with Activity against Multidrug-Resistant Streptococcus pneumoniae by SAMUEL RAJ, V, TARANI KANTA BARMAN, SURASE, Yogesh B, VENKATARAMANAN, R, CHAKRABARTI, Anjan, DAS, Biswajit, BHATNAGAR, Pradip K, KALIA, Vandana, PURNAPATRE, Kedar, DUBE, Smita, RAMKUMAR, G, BHATEJA, Pragya, MATHUR, Tarun, CHAIRA, Tridib, UPADHYAY, Dilip J

“…We present here the novel ketolide RBx 14255, a semisynthetic macrolide derivative obtained by the derivatization of clarithromycin, for its in vitro and in…”
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