Search Results - "UNEMI, N"
-
1
In Vitro and In Vivo Activities of Syn2836, Syn2869, Syn2903, and Syn2921: New Series of Triazole Antifungal Agents
Published in Antimicrobial Agents and Chemotherapy (01-09-2001)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
2
Postsurgical oral administration of uracil and tegafur inhibits progression of micrometastasis of human breast cancer cells in nude mice
Published in Clinical cancer research (01-05-1997)“…We recently established a metastasis model in nude mice using the MKL-4 cell line, a contransfectant of the MCF-7 human breast cancer cell line with fgf-4 and…”
Get full text
Journal Article -
3
Experimental postoperative adjuvant chemotherapy by UFT using primary tumor amputation model
Published in International journal of molecular medicine (01-04-2000)“…We evaluated the postoperative adjuvant chemotherapy by UFT using the primary tumor amputation-pulmonary metastasis model. When Lewis lung carcinoma (LLC)…”
Get more information
Journal Article -
4
Development of beta-lactamase inhibitors
Published in Nihon rinshō (01-05-1997)“…The proportion of beta-lactamase producing bacteria in each species of clinical isolates is high (over 90%) in these years. According to the survey of…”
Get more information
Journal Article -
5
Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats
Published in Cancer research (Chicago, Ill.) (01-06-1996)“…The purpose of this study was to establish a nude rat orthotopic (organ-specific) human colorectal cancer model as an in vivo secondary screen for general…”
Get full text
Journal Article -
6
Prolongation of survival and antitumor activity of antitumor drugs in murine cancer cachexia model
Published in Gan to kagaku ryoho (01-06-1996)“…We examined the activity of UFT, ADM and MMC, which are used for colon tumors, in terms of their prolongation of the survival period, growth inhibition of the…”
Get more information
Journal Article -
7
Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--l-leucovorin factors enhancing cytotoxic activity of 5-fluorouracil
Published in Gan to kagaku ryoho (01-11-1995)“…The relationship between augmentation of cytotoxic activity of 5-fluorouracil (FUra) by l-leucovorin (l-LV) and combination schedule was investigated using…”
Get more information
Journal Article -
8
Inhibition of prostate cancer growth in nude mice by hormone and chemotherapy
Published in Gan to kagaku ryoho (01-09-1996)“…The combined effect of hormone and cytotoxic therapy on the growth of prostate cancer PC-3 in nude mice was investigated. PC-3 cell was derived from the bone…”
Get more information
Journal Article -
9
Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--growth-inhibitory activity of combination against human tumor xenograft
Published in Gan to kagaku ryoho (01-11-1995)“…Combination chemotherapy with FUra and LV has been reported as a useful treatment for patients suffering from colon carcinoma. Usually, both FUra and LV are…”
Get more information
Journal Article -
10
Antitumor activity and low intestinal toxicity of S-1, a new formulation of oral tegafur, in experimental tumor models in rats
Published in Cancer chemotherapy and pharmacology (1997)“…S-1, a new oral antitumor agent, is composed of 1-(2-tetrahydrofuryl)-5-fluorouracil (Tegafur, FT), 5-chloro-2,4-dihydroxypyridine (CDHP) and potassium oxonate…”
Get full text
Journal Article -
11
Experimental evaluation of combination chemotherapy with UFT and cisplatin for lung cancer
Published in Gan to kagaku ryoho (01-06-1994)“…Combined treatment of UFT with cisplatin (CDDP) achieved remarkable elongation of survival time of BDF1 mice, which were intravenously transplanted with Lewis…”
Get more information
Journal Article -
12
Antimetastatic effects of UFT on murine liver metastasis model using L5178YHM lymphoma
Published in Gan to kagaku ryoho (01-12-1996)Get more information
Journal Article -
13
The significance of measuring inhibition of thymidylate synthase activity as a parameter for antitumor activity of 5-fluorouracil derivatives
Published in Gan to kagaku ryoho (01-07-1988)“…We investigated the relationships between antitumor activity and the inhibition of Thymidylate Synthase (TS) activity after oral administration of…”
Get more information
Journal Article -
14
Antitumor and anticachectic activity of UFT in BALB/c mice bearing colon 26 adenocarcinoma
Published in Gan to kagaku ryoho (01-09-1994)“…We established a cancer cachexia model in BALB/c mice bearing Colon 26 and examined antitumor and anticachectic activity of UFT. The mice bearing Colon 26…”
Get more information
Journal Article -
15
Differential effects of 5-fluorouracil analogs on humoral and cell-mediated responses in mice: augmentation of delayed hypersensitivity response against picryl chloride by 1,3-bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione (FD-1), a new anti-tumor drug
Published in Journal of clinical & laboratory immunology (01-11-1980)“…The inhibitory effects of three fluorinated pyrimidines, i.e., 5-fluorouracil (FU), N1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur, FT), and…”
Get more information
Journal Article -
16
Effects of a fluorinated pyrimidinedione anti-cancer drug, 5-fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione (FT), and related compounds on nigro-striatal dopaminergic neurons in the central nervous system
Published in Archives internationales de pharmacodynamie et de thérapie (01-01-1985)“…The cause of the side effects of 5-fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione (FT) on the central nervous system (CNS), and especially the…”
Get more information
Journal Article -
17
MJ347-81F4 A & B, novel antibiotics from Amycolatopsis sp.: taxonomic characteristics, fermentation, and antimicrobial activity
Published in Journal of antibiotics (01-08-1998)“…Strain MJ347-81F4 has been found to produce two new cyclic thiazolyl peptide antibiotics, components A and B. Taxonomic studies including morphological and…”
Get more information
Journal Article -
18
General pharmacological properties of UFT, a new type of anti-cancer agent consisting of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT) and uracil. I: Pharmacological analysis of the combined effect of FT and uracil
Published in Arzneimittel-Forschung (1981)“…The pharmacological properties of a new type of anti-cancer agent, 1-(2-tetrahydrofuryl)-5-fluorouracil (FT) and uracil (U), in a molar ratio of 1:4, were…”
Get more information
Journal Article -
19
-
20
Augmentation of the chemotherapeutic effectiveness of UFT, a combination of tegafur [1-(2-tetrahydrofuryl)-5-fluorouracil] with uracil, by oral l-leucovorin
Published in Anticancer research (01-01-1997)“…UFT, combination of tegafur [1-(2-tetrahydrofuryl)-5-fluorouracil] with uracil, is widely-used as an anti-neoplastic agent in Japan. We evaluated the…”
Get more information
Journal Article