Search Results - "UN JU JUNG"
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Probiotics L. plantarum and L. curvatus in Combination Alter Hepatic Lipid Metabolism and Suppress Diet‐Induced Obesity
Published in Obesity (Silver Spring, Md.) (01-12-2013)“…Objective: To determine the effects of naturally derived probiotic strains individually or combination on a short‐term diet‐induced obesity model. Design and…”
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2
Antihyperglycemic and antioxidant properties of caffeic acid in db/db mice
Published in The Journal of pharmacology and experimental therapeutics (01-08-2006)“…This study investigated the blood glucose-lowering effect and antioxidant capacity of caffeic acid in C57BL/KsJ-db/db mice. Caffeic acid induced a significant…”
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3
Obesity and its metabolic complications: the role of adipokines and the relationship between obesity, inflammation, insulin resistance, dyslipidemia and nonalcoholic fatty liver disease
Published in International journal of molecular sciences (11-04-2014)“…Accumulating evidence indicates that obesity is closely associated with an increased risk of metabolic diseases such as insulin resistance, type 2 diabetes,…”
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4
Mitochondrial Dysfunction as a Driver of Cognitive Impairment in Alzheimer’s Disease
Published in International journal of molecular sciences (01-05-2021)“…Alzheimer’s disease (AD) is the most frequent cause of age-related neurodegeneration and cognitive impairment, and there are currently no broadly effective…”
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5
Sarcopenic Obesity: Involvement of Oxidative Stress and Beneficial Role of Antioxidant Flavonoids
Published in Antioxidants (08-05-2023)“…Sarcopenic obesity, which refers to concurrent sarcopenia and obesity, is characterized by decreased muscle mass, strength, and performance along with…”
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6
Myricitrin Ameliorates Hyperglycemia, Glucose Intolerance, Hepatic Steatosis, and Inflammation in High-Fat Diet/Streptozotocin-Induced Diabetic Mice
Published in International journal of molecular sciences (09-03-2020)“…To test the hypothesis that myricitrin (MYR) improves type 2 diabetes, we examined the effect of MYR on hyperglycemia, glucose intolerance, hepatic steatosis,…”
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7
Differential effects of low-dose resveratrol on adiposity and hepatic steatosis in diet-induced obese mice
Published in British journal of nutrition (28-12-2012)“…Consumption of a high-fat diet (HFD) enriched in saturated fat induces excessive weight gain due to adiposity, which can lead to metabolic complications, as…”
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Honokiol Improves Insulin Resistance, Hepatic Steatosis, and Inflammation in Type 2 Diabetic db / db Mice
Published in International journal of molecular sciences (09-05-2019)“…This study focuses on the effect of honokiol (HON) on glucose homeostasis, insulin resistance, dyslipidemia, hepatic steatosis, and inflammation in type 2…”
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Apigenin Ameliorates Dyslipidemia, Hepatic Steatosis and Insulin Resistance by Modulating Metabolic and Transcriptional Profiles in the Liver of High-Fat Diet-Induced Obese Mice
Published in Nutrients (19-05-2016)“…Several in vitro and in vivo studies have reported the anti-inflammatory, anti-diabetic and anti-obesity effects of the flavonoid apigenin. However, the…”
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10
Protective effects of p-coumaric acid against high-fat diet-induced metabolic dysregulation in mice
Published in Biomedicine & pharmacotherapy (01-10-2021)“…p-Coumaric acid (PC), a naturally occurring phytochemical, possesses antioxidant and anti-inflammatory properties; however, the mechanisms underlying its…”
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11
Differences in metabolic biomarkers in the blood and gene expression profiles of peripheral blood mononuclear cells among normal weight, mildly obese and moderately obese subjects
Published in British journal of nutrition (28-09-2016)“…We compared metabolic biomarkers in the blood and peripheral blood mononuclear cell (PBMC) gene expression profiles among normal weight (BMI, 18·5–23 kg/m2),…”
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12
Effect of citrus flavonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice
Published in The international journal of biochemistry & cell biology (2006)“…Flavonoids have been identified as the antidiabetic components in a number of traditional ethnic remedies. However, the mechanisms whereby these compounds…”
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13
Efficacy of nobiletin in improving hypercholesterolemia and nonalcoholic fatty liver disease in high-cholesterol diet-fed mice
Published in Nutrition research and practice (01-08-2021)“…BACKGROUND/OBJECTIVESNobiletin (NOB), a citrus flavonoid, is reported to have beneficial effects on cardiovascular and metabolic health. However, there is…”
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14
Pathophysiological Role of Microglial Activation Induced by Blood-Borne Proteins in Alzheimer's Disease
Published in Biomedicines (07-05-2023)“…The blood-brain barrier (BBB) restricts entry of neurotoxic plasma components, blood cells, and pathogens into the brain, leading to proper neuronal…”
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15
Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabetic db/db mice
Published in Molecular nutrition & food research (01-09-2008)“…We investigated the effect of curcumin on insulin resistance and glucose homeostasis in male C57BL/KsJ-db/db mice and their age-matched lean non-diabetic db/+…”
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Induction of GDNF and BDNF by hRheb(S16H) Transduction of SNpc Neurons: Neuroprotective Mechanisms of hRheb(S16H) in a Model of Parkinson’s Disease
Published in Molecular neurobiology (01-04-2015)“…The transduction of dopaminergic (DA) neurons with human ras homolog enriched in brain, which has a S16H mutation [hRheb(S16H)] protects the nigrostriatal DA…”
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d-Allulose supplementation normalized the body weight and fat-pad mass in diet-induced obese mice via the regulation of lipid metabolism under isocaloric fed condition
Published in Molecular nutrition & food research (01-07-2016)“…Scope A number of findings suggest that zero‐calorie d‐allulose, also known as d‐psicose, has beneficial effects on obesity‐related metabolic disturbances…”
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Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK
Published in Life sciences (1973) (04-11-2013)“…This study investigated the hepatoprotective effects of low doses of curcumin against liver damage induced by chronic alcohol intake and a high-fat diet. We…”
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Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat–fed hamsters
Published in Metabolism, clinical and experimental (01-11-2008)“…Abstract This study investigated the effect of curcumin (0.05-g/100-g diet) supplementation on a high-fat diet (10% coconut oil, 0.2% cholesterol, wt/wt) fed…”
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20
Naringin protects the nigrostriatal dopaminergic projection through induction of GDNF in a neurotoxin model of Parkinson's disease
Published in The Journal of nutritional biochemistry (01-07-2014)“…This study investigated the effect of naringin, a major flavonoid in grapefruit and citrus fruits, on the degeneration of the nigrostriatal dopaminergic (DA)…”
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