Search Results - "UMENO, YUKIHIKO"

High-pressure liquid chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometric determination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur by Marunaka, T, Umeno, Y, Yoshida, K, Nagamachi, M, Minami, Y, Fujii, S

“…Oral administration of uracil plus ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] has a greater antitumor effect than that of ftorafur alone. A…”
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Quantitative determination of 1,3-bis(tetrahydro-2- furanyl)-5-fluoro-2,4-pyrimidinedione and its metabolites in plasma by high-pressure liquid chromatography and gas chromatography-mass fragmentography by Marunaka, T, Umeno, Y

“…1,3-Bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione has been developed clinically as an antitumor agent. A high-pressure liquid chromatographic method…”
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Analysis of pyrimidine bases in biological materials by gas chromatography-mass spectrometry by Marunaka, T, Umeno, Y, Minami, Y

“…Simultaneous detection by a combination of gas chromatography-mass fragmentography and gas chromatography-mass spectrometry for total ion monitoring was…”
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Combinative Improving Effect of Increased Solubility and the Use of Absorption Enhancers on the Rectal Absorption of Uracil in Beagle Dogs by TAKEICHI, Yoh'ichiro, BABA, Kazuhiko, KINOUCHI, Yoshihito, IIDA, Yuichi, UMENO, Yukihiko, MURANISHI, Shozo, NAKAI, Yoshinobu

“…An improvement of the rectal absorption of uracil was examined by the application of absorption enhancers in addition to the increased solubility of…”
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Acidic Degradation of Cefodizime (THR-221) and Structural Elucidation of the Products. I by MARUNAKA, Teruyoshi, MATSUSHIMA, Eiji, MINAMI, Yoshinori, AZUMA, Ryotaro, YOSHIDA, Ken-ichiro, UMENO, Yukihiko

“…Cefodizime sodium (CDZM, THR-221) is a new semi-synthetic cephalosporin. The acidic degradation of cefodizime and structural elucidation of the degradation…”
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Metabolism of Tegafur in Rat Liver Observed by in vivo 19F Magnetic Resonance Spectroscopy and Chromatography by Harada, Masafumi, Nishitani, Hiromu, Koga, Keiko, Miura, Iwao, Umeno, Yukihiko

“…Metabolism of tegafur in the rat liver was observed by in‐vivo19F magnetic resonance spectroscopy (MRS). After MRS observation, tegafur and q‐fluorouracil…”
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Gas Chromatographic-Mass Fragmentographic Determination of 5-Fluorouracil as a Metabolite of New 5-Fluorouracil Derivatives by MARUNAKA, TERUYOSHI, UMENO, YUKIHIKO

“…5-Fluoro-5'-deoxyuridine and ethyl (±)-6-n-butoxy-5-fluoro-5, 6-dihydrouracil-γ-5-carboxylate are new pro-drug forms of 5-fluorouracil that have been developed…”
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Alkaline and Neutral Degradation of Cefodizime (THR-221) and Structural Elucidation of the Products. II by MATSUSHIMA, Eiji, MINAMI, Yoshinori, AZUMA, Ryotaro, YOSHIDA, Ken-ichiro, UMENO, Yukihiko, MARUNAKA, Teryuyoshi

“…Cefodizime sodium (CDZM, THR-221) is a new semi-synthetic cephalosporin. The alkaline and neutral degradation of cefodizime and structural elucidation of its…”
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Identification of Metabolites of 1-(Tetrahydro-2-furanyl)-5-fluorouracil (FT-207) formed in Vitro by Rat Liver Microsomes by MARUNAKA, TERUYOSHI, MINAMI, YOSHINORI, UMENO, YUKIHIKO, YASUDA, AKIO, SATO, TOSHIYUKI, FUJII, SETSURO

“…Four metabolites of the antitumor agent 1-(tetrahydro-2-furanyl)-5-fluorouracil, formed in vitro by rat liver microsomes, were isolated by thin-layer…”
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Gas chromatographic-negative-ion chemical ionization mass spectrometric determination of a new dihydropyridine calcium antagonist (MPC-1304) and its metabolites in human plasma and urine by Umeno, Y, Matsushima, E, Maniwa, M, Marunaka, T

“…A gas chromatographic-negative-ion chemical ionization mass spectrometric method was developed for the determination of a new calcium antagonist, (+/-)-methyl…”
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Method of measurement for tazobactam/piperacillin concentration in body fluid by bioassay and high-performance liquid chromatography by Sakawa, Kumiko, Sasaki, Toru, Otani, Toshio, Hyodo, Akio, Ishida, Naobumi, Nishikawa, Masako, Umeno, Yukihiko

“…We established a microbiological assay method and high-performance liquid chromatography (HPLC) method for the quantitative determination of…”
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Pharmacokinetic studies of propiverine hydrochloride (2). Metabolism in rats after single oral administration of P-4 by YAMAMOTO, Yoshio, MINAMI, Yoshinori, YOSHIDA, Masahiko, TSUDA, Masuhiro, UDA, Kazuhiko, SHINDO, Takashi, UMENO, Yukihiko, KAWAGUCHI, Yasuro

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Determination of 5-fluorouracil and pyrimidine bases in plasma by gas chromatography-chemical ionization-mass fragmentography by Marunaka, T, Umeno, Y

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Simultaneous determination of phenylbutazone and its metabolites in plasma and urine by high-performance liquid chromatography by Marunaka, T, Shibata, T, Minami, Y, Umeno, Y

“…A high-performance liquid chromatographic method was developed for the simultaneous determination of phenylbutazone and its metabolites, oxyphenbutazone and…”
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GLC-mass fragmentographic determination of mannitol and sorbitol in plasma by Marunaka, T, Matsushima, E, Umeno, Y, Minami, Y

“…A GLC-mass fragmentographic method was developed for the simultaneous determination of mannitol and sorbitol as their n-butyldiboronate derivatives in plasma…”
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Gas chromatographic--mass fragmentographic determination of homopantothenic acid in plasma by Umeno, Y, Nakai, K, Matsushima, E, Marunaka, T

“…A gas chromatographic--mass fragmentographic method was developed for the determination of homopantothenic acid in plasma. Acidified plasma was deproteinized…”
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Determination of pentazirinocyclodiphosphathiazene in biological fluids by high-performance liquid chromatography by Matsushima, E, Umeno, Y, Marunaka, T, Akagi, H

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High-performance liquid chromatographic determination of proglumide in plasma by Marunaka, T, Minami, Y, Umeno, Y, Matsushima, E

“…A rapid and sensitive method for determining the anticholinergic agent, proglumide, in plasma by high-performance liquid chromatography is described. Samples…”
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Metabolism of Tegafur in Rat Liver Observed by in vivo 19 F Magnetic Resonance Spectroscopy and Chromatography by Harada, Masafumi, Nishitani, Hiromu, Koga, Keiko, Miura, Iwao, Umeno, Yukihiko

“…Metabolism of tegafur in the rat liver was observed by in‐vivo 19 F magnetic resonance spectroscopy (MRS). After MRS observation, tegafur and q‐fluorouracil…”
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Simultaneous high-performance liquid chromatographic determination of suxibuzone and its metabolites in plasma and urine by Marunaka, T, Shibata, T, Minami, Y, Umeno, Y, Shindo, T

“…A high-performance liquid chromatographic method is described for the simultaneous determination of the anti-inflammatory agent suxibuzone and its metabolites,…”
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