Search Results - "ULRICH, Alexis"

Definition and grading of anastomotic leakage following anterior resection of the rectum: A proposal by the International Study Group of Rectal Cancer by Rahbari, Nuh N., MD, Weitz, Jürgen, MD, Hohenberger, Werner, MD, Heald, Richard J., MD, Moran, Brendan, MD, Ulrich, Alexis, MD, Holm, Torbjörn, MD, Wong, W. Douglas, MD, Tiret, Emmanuel, MD, Moriya, Yoshihiro, MD, Laurberg, Søren, MD, den Dulk, Marcel, MD, van de Velde, Cornelis, MD, Büchler, Markus W., MD

“…Background Anastomotic leakage represents a major complication after anterior resection of the rectum. The incidence of anastomotic leakage varies considerably…”
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Use and results of consensus definitions in pancreatic surgery: A systematic review by Harnoss, Julian C., MD, Ulrich, Alexis B., MD, Harnoss, Jonathan M., MD, Diener, Markus K., MD, Büchler, Markus W., MD, Welsch, Thilo, MD

“…Background Because of the lack of standardized definitions of complications in gastrointestinal operations, consensus definitions have been developed in recent…”
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Surgical strategies in true adenocarcinoma of the esophagogastric junction (AEG II): thoracoabdominal or abdominal approach? by Blank, Susanne, Schmidt, Thomas, Heger, Patrick, Strowitzki, Moritz J., Sisic, Leila, Heger, Ulrike, Nienhueser, Henrik, Haag, Georg Martin, Bruckner, Thomas, Mihaljevic, André L., Ott, Katja, Büchler, Markus W., Ulrich, Alexis

“…Background The optimal surgical approach for adenocarcinoma directly at the esophagogastric junction (AEG II) is still under debate. This study aims to…”
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The TRIANGLE operation – radical surgery after neoadjuvant treatment for advanced pancreatic cancer: a single arm observational study by Hackert, Thilo, Strobel, Oliver, Michalski, Christoph W., Mihaljevic, André L., Mehrabi, Arianeb, Müller-Stich, Beat, Berchtold, Christoph, Ulrich, Alexis, Büchler, Markus W.

“…Neoadjuvant therapy is an important strategy for locally advanced pancreatic cancer (PDAC) as resection rates increase with modern chemotherapy regimens even…”
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In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer by Kather, Jakob Nikolas, Poleszczuk, Jan, Suarez-Carmona, Meggy, Krisam, Johannes, Charoentong, Pornpimol, Valous, Nektarios A, Weis, Cleo-Aron, Tavernar, Luca, Leiss, Florian, Herpel, Esther, Klupp, Fee, Ulrich, Alexis, Schneider, Martin, Marx, Alexander, Jäger, Dirk, Halama, Niels

“…Despite the fact that the local immunological microenvironment shapes the prognosis of colorectal cancer, immunotherapy has shown no benefit for the vast…”
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Validation of the International Study Group of Rectal Cancer definition and severity grading of anastomotic leakage by Kulu, Yakup, MD, Ulrich, Alexis, MD, Bruckner, Thomas, PhD, Contin, Pietro, MD, Welsch, Thilo, MD, Rahbari, Nuh N., MD, Büchler, Markus W., MD, Weitz, Jürgen, MD

“…Background The International Study Group of Rectal Cancer (ISREC) has proposed a generally applicable definition and severity grading of (AL) after…”
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VEGFR1 + Metastasis-Associated Macrophages Contribute to Metastatic Angiogenesis and Influence Colorectal Cancer Patient Outcome by Freire Valls, Aida, Knipper, Karl, Giannakouri, Evangelia, Sarachaga, Víctor, Hinterkopf, Sascha, Wuehrl, Michael, Shen, Ying, Radhakrishnan, Praveenkumar, Klose, Johannes, Ulrich, Alexis, Schneider, Martin, Augustin, Hellmut G, Ruiz de Almodovar, Carmen, Schmidt, Thomas

“…To investigate the clinical relevance of macrophages in liver metastasis of colorectal cancer and their influence on angiogenesis and patient survival…”
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Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare study by Liesenfeld, David B, Grapov, Dmitry, Fahrmann, Johannes F, Salou, Mariam, Scherer, Dominique, Toth, Reka, Habermann, Nina, Böhm, Jürgen, Schrotz-King, Petra, Gigic, Biljana, Schneider, Martin, Ulrich, Alexis, Herpel, Esther, Schirmacher, Peter, Fiehn, Oliver, Lampe, Johanna W, Ulrich, Cornelia M

“…Metabolic and transcriptomic differences between visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) compartments, particularly in the context…”
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Splenectomy reduces lung metastases and tumoral and metastatic niche inflammation by Stöth, Manuel, Freire Valls, Aida, Chen, Mingyi, Hidding, Sarah, Knipper, Karl, Shen, Ying, Klose, Johannes, Ulrich, Alexis, Ruiz de Almodovar, Carmen, Schneider, Martin, Schmidt, Thomas

“…The immune microenvironment plays a crucial role in supporting tumor growth and metastasis. Tumor‐associated macrophages (TAMs) and neutrophils (TANs) are…”
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Granulin: An Invasive and Survival-Determining Marker in Colorectal Cancer Patients by Klupp, Fee, Kahlert, Christoph, Franz, Clemens, Halama, Niels, Schleussner, Nikolai, Wirsik, Naita M., Warth, Arne, Schmidt, Thomas, Ulrich, Alexis B.

“…Background: Granulin is a secreted, glycosylated peptide—originated by cleavage from a precursor protein—which is involved in cell growth, tumor invasion and…”
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Smoking and survival of colorectal cancer patients: Population‐based study from Germany by Walter, Viola, Jansen, Lina, Hoffmeister, Michael, Ulrich, Alexis, Chang‐Claude, Jenny, Brenner, Hermann

“…Current evidence on the association between smoking and colorectal cancer (CRC) prognosis after diagnosis is heterogeneous and few have investigated…”
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Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery by Schmitt, Felix C F, Brenner, Thorsten, Uhle, Florian, Loesch, Svenja, Hackert, Thilo, Ulrich, Alexis, Hofer, Stefan, Dalpke, Alexander H, Weigand, Markus A, Boutin, Sébastien

“…Postoperative complications are of great relevance in daily clinical practice, and the gut microbiome might play an important role by preventing pathogens from…”
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Plasma metabolites associated with colorectal cancer: A discovery‐replication strategy by Geijsen, Anne J.M.R., Brezina, Stefanie, Keski‐Rahkonen, Pekka, Baierl, Andreas, Bachleitner‐Hofmann, Thomas, Bergmann, Michael M., Boehm, Juergen, Brenner, Hermann, Chang‐Claude, Jenny, Duijnhoven, Fränzel J.B., Gigic, Biljana, Gumpenberger, Tanja, Hofer, Philipp, Hoffmeister, Michael, Holowatyj, Andreana N., Karner‐Hanusch, Judith, Kok, Dieuwertje E., Leeb, Gernot, Ulvik, Arve, Robinot, Nivonirina, Ose, Jennifer, Stift, Anton, Schrotz‐King, Petra, Ulrich, Alexis B., Ueland, Per Magne, Kampman, Ellen, Scalbert, Augustin, Habermann, Nina, Gsur, Andrea, Ulrich, Cornelia M.

“…Colorectal cancer is known to arise from multiple tumorigenic pathways; however, the underlying mechanisms remain not completely understood. Metabolomics is…”
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Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model by Klose, Johannes, Trefz, Stefan, Wagner, Tobias, Steffen, Luca, Preißendörfer Charrier, Arsalie, Radhakrishnan, Praveen, Volz, Claudia, Schmidt, Thomas, Ulrich, Alexis, Dieter, Sebastian M, Ball, Claudia, Glimm, Hanno, Schneider, Martin

“…Salinomycin is a polyether antibiotic with selective activity against human cancer stem cells. The impact of salinomycin on patient-derived primary human…”
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Postoperative follow-up programs improve survival in curatively resected gastric and junctional cancer patients: a propensity score matched analysis by Sisic, Leila, Strowitzki, Moritz J., Blank, Susanne, Nienhueser, Henrik, Dorr, Sara, Haag, Georg Martin, Jäger, Dirk, Ott, Katja, Büchler, Markus W., Ulrich, Alexis, Schmidt, Thomas

“…Background To date there is no evidence that more intensive follow-up after surgery for esophagogastric adenocarcinoma translates into improved survival. This…”
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Circulating tryptophan-kynurenine pathway metabolites are associated with all-cause mortality among patients with stage I-III colorectal cancer by Damerell, Victoria, Klaassen-Dekker, Niels, Brezina, Stefanie, Ose, Jennifer, Ulvik, Arve, van Roekel, Eline H, Holowatyj, Andreana N, Baierl, Andreas, Böhm, Jürgen, Bours, Martijn J L, Brenner, Hermann, de Wilt, Johannes H W, Grady, William M, Habermann, Nina, Hoffmeister, Michael, Keski-Rahkonen, Pekka, Lin, Tengda, Schirmacher, Peter, Schrotz-King, Petra, Ulrich, Alexis B, van Duijnhoven, Fränzel J B, Warby, Christy A, Shibata, David, Toriola, Adetunji T, Figueiredo, Jane C, Siegel, Erin M, Li, Christopher I, Gsur, Andrea, Kampman, Ellen, Schneider, Martin, Ueland, Per M, Weijenberg, Matty P, Ulrich, Cornelia M, Kok, Dieuwertje E, Gigic, Biljana

“…Alterations within the tryptophan-kynurenine metabolic pathway have been linked to the etiology of colorectal cancer (CRC), but the relevance of this pathway…”
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Overexpression of ZEB2 at the Invasion Front of Colorectal Cancer Is an Independent Prognostic Marker and Regulates Tumor Invasion In Vitro by KAHLERT, Christoph, LAHES, Saleh, REISSFELDER, Christoph, KLUPP, Fee, FRITZMANN, Johannes, WUNDER, Christina, BENNER, Axel, KLOOR, Matthias, HUTH, Cathrin, CONTIN, Pietro, ULRICH, Alexis, KOCH, Moritz, RADHAKRISHNAN, Praveen, WEITZ, Jürgen, DUTTA, Shamik, MOGLER, Carolin, HERPEL, Esther, BRAND, Karsten, STEINERT, Gunnar, SCHNEIDER, Martin, MOLLENHAUER, Martin

“…Epithelial-to-mesenchymal transition (EMT) plays a pivotal role in tumor invasion and dissemination. EMT occurs predominantly at the tumor edge where it is…”
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Diverting Stoma After Low Anterior Resection: More Arguments in Favor by Ulrich, Alexis B, Seiler, Christoph, Rahbari, Nuh, Weitz, Jürgen, Büchler, Markus W

“…PURPOSE:The necessity of a protective stoma in patients undergoing low anterior resection with total mesorectal excision for primary rectal cancer is discussed…”
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Neoadjuvant Therapy Improves Outcomes in Locally Advanced Signet-Ring-Cell Containing Esophagogastric Adenocarcinomas by Heger, Ulrike, Sisic, Leila, Nienhüser, Henrik, Blank, Susanne, Hinz, Ulf, Haag, Georg Martin, Ott, Katja, Ulrich, Alexis, Büchler, Markus W., Schmidt, Thomas

“…Background Only a few studies have analyzed multimodal treatment concepts in the subgroup of signet-ring-cell containing upper gastrointestinal (GI) cancer…”
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Detailed resolution analysis reveals spatial T cell heterogeneity in the invasive margin of colorectal cancer liver metastases associated with improved survival by Berthel, Anna, Zoernig, Inka, Valous, Nektarios A., Kahlert, Christoph, Klupp, Fee, Ulrich, Alexis, Weitz, Juergen, Jaeger, Dirk, Halama, Niels

“…On a broader scale, T cell density and localization in colorectal cancer liver metastases have prognostic and predictive implications. As T cell distribution…”
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