Search Results - "ULLMAN, M. DAVID"
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Lipid Sorting by Ceramide Structure from Plasma Membrane to ER for the Cholera Toxin Receptor Ganglioside GM1
Published in Developmental cell (11-09-2012)“…The glycosphingolipid GM1 binds cholera toxin (CT) on host cells and carries it retrograde from the plasma membrane (PM) through endosomes, the trans-Golgi…”
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Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology
Published in Brain research (01-10-2004)“…Parkinson's disease (PD) is a slowly progressing neurodegenerative disorder with no clear etiology. Pathological hallmarks of the disease include the loss of…”
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Retinoid quantification by HPLC/MS(n)
Published in Journal of lipid research (01-07-2002)“…Retinoic acid (RA) mediates most of the biological effects of vitamin A that are essential for vertebrate survival. It acts through binding to receptors that…”
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Insulin degrading enzyme is localized predominantly at the cell surface of polarized and unpolarized human cerebrovascular endothelial cell cultures
Published in Journal of neuroscience research (15-05-2006)“…Insulin degrading enzyme (IDE) is expressed in the brain and may play an important role there in the degradation of the amyloid beta peptide (Aβ). Our results…”
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Retinoid quantification by HPLC/MSn
Published in Journal of lipid research (01-07-2002)“…Retinoic acid (RA) mediates most of the biological effects of vitamin A that are essential for vertebrate survival. It acts through binding to receptors that…”
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6
Insulin degrading enzyme is expressed in the human cerebrovascular endothelium and in cultured human cerebrovascular endothelial cells
Published in Neuroscience letters (16-11-2004)“…Insulin degrading enzyme (IDE) is found in the cytosol, peroxisomes and plasma membrane of many cells. Although it preferentially cleaves insulin it can also…”
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Specific up-regulation of GADD153/CHOP in 1-methyl-4-phenyl-pyridinium-treated SH-SY5Y cells
Published in Journal of neuroscience research (15-06-2002)“…Growth arrest DNA damage‐inducible 153 (GADD153) expression was increased in 1‐methyl‐4‐phenyl‐pyridinium (MPP+)‐treated human SH‐SY5Y neuroblastoma cells as…”
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Upregulation of clusterin/apolipoprotein J in lactacystin-treated SH-SY5Y cells
Published in Journal of neuroscience research (15-02-2005)“…Clusterin (apolipoprotein J) is a highly conserved, multifunctional, vertebrate glycoprotein. Several isoforms of clusterin have been described including the…”
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cDNA Microarray analysis of changes in gene expression associated with MPP+ toxicity in SH-SY5Y cells
Published in Neurochemical research (01-12-2003)“…cDNA microarray analysis of 1-methyl-4-phenyl-pyridinium (MPP+) toxicity (1 mM, 72 h) in undifferentiated SH-SY5Y cells identified 48 genes that displayed a…”
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Ethanol increases retinoic acid production in cerebellar astrocytes and in cerebellum
Published in Brain research. Developmental brain research (25-11-2004)“…Several characteristics of fetal alcohol syndrome (FAS) are similar to the teratogenic effects of retinoic acid (RA) exposure. It has been suggested that FAS…”
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Decreased expression of the NADH:ubiquinone oxidoreductase (complex I) subunit 4 in 1-methyl-4-phenylpyridinium -treated human neuroblastoma SH-SY5Y cells
Published in Neuroscience letters (29-06-2001)“…Oxidative stress and mitochondrial dysfunction have been implicated in Parkinson's disease (PD) pathology. NADH:ubiquinone oxidoreductase (complex I) (EC…”
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Nervous system involvement in Fabry's disease: clinicopathological and biochemical correlation
Published in Annals of neurology (01-05-1988)“…A detailed neuropathological and biochemical study was performed to evaluate the accumulation of ceramide trihexoside within the central and peripheral nervous…”
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Androgens and Dry Eye in Sjögren's Syndromea
Published in Annals of the New York Academy of Sciences (01-06-1999)“…Sjögren's syndrome is an extremely complex and currently incurable autoimmune disorder, which occurs primarily in females, and is associated with lacrimal…”
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Effect of Exogenous GM1 on Ethanol Sensitivity in Selectively Bred Mouse Lines
Published in Alcoholism, clinical and experimental research (01-06-1997)“…Ethanol sensitive long‐sleep (LS) and ethanol resistant short‐sleep (SS) mice are lines that have been genetically selected for differential central nervous…”
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Effect of androgen deficiency on the human meibomian gland and ocular surface
Published in The journal of clinical endocrinology and metabolism (01-12-2000)“…The purpose of this study was to determine whether the chronic use of antiandrogen medications leads to meibomian gland dysfunction, altered lipid profiles in…”
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Androgen Influence on the Meibomian Gland
Published in Investigative ophthalmology & visual science (01-11-2000)“…The hypothesis in the study was that androgens control meibomian gland function, regulate the quality and/or quantity of lipids produced by this tissue, and…”
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The Enzymatic Formation of Sphingomyelin from Ceramide and Lecithin in Mouse Liver
Published in The Journal of biological chemistry (10-03-1974)“…The conversion of 14C-labeled fatty acylsphingosine and phosphatidyl[14C]choline to sphingomyelin could be demonstrated in lyophilized microsomes from mouse…”
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Androgens and Dry Eye in Sjögren's Syndrome
Published in Annals of the New York Academy of Sciences (22-06-1999)“…Sjögren's syndrome is an extremely complex and currently incurable autoimmune disorder, which occurs primarily in females, and is associated with lacrimal…”
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Biochemical studies in a patient with subacute neuropathic Gaucher disease without visceral glucosylceramide storage
Published in Pediatric research (01-05-1983)“…Autopsy samples were obtained from a 12.5-year-old girl who died with a neurologic disorder consisting of myoclonus, myoclonic epilepsy, spasticity,…”
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