Search Results - "UKNIS, Marc E"

Nanofiltered C1-Esterase Inhibitor for the Acute Management and Prevention of Hereditary Angioedema Attacks due to C1-Inhibitor Deficiency in Children by Lumry, William, MD, FAAAAI, FACAAI, Manning, Michael E., MD, FAAAAI, FACAAI, Hurewitz, David S., MD, FACP, FAAAAI, FACAAI, Davis-Lorton, Mark, MD, FAAAAI, FACAAI, Fitts, David, MPH, PhD, Kalfus, Ira N., MD, Uknis, Marc E., MD, FACS

“…Objectives To evaluate the use of Cinryze (nanofiltered C1-esterase inhibitor [C1 INH-nf]) for the acute management and prevention of hereditary angioedema…”
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Cytomegalovirus in transplantation - challenging the status quo by Fishman, Jay A, Emery, Vincent, Freeman, Richard, Pascual, Manuel, Rostaing, Lionel, Schlitt, Hans J, Sgarabotto, Dino, Torre-Cisneros, Julian, Uknis, Marc E

“…:  Background:  Cytomegalovirus (CMV) infection of solid organ transplant (SOT) recipients causes both ‘‘direct’’ and ‘‘indirect’’ effects including allograft…”
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Alpha‐1‐antitrypsin in cell and organ transplantation by Berger, Mel, Liu, Mingyao, Uknis, Marc E., Koulmanda, Maria

“…Limited availability of donor organs and risk of ischemia‐reperfusion injury (IRI) seriously restrict organ transplantation. Therapeutics that can prevent or…”
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Oral ganciclovir versus low-dose valganciclovir for prevention of cytomegalovirus disease in recipients of kidney and pancreas transplants by WENG, Francis L, PATEL, Anup M, WANCHOO, Rimda, BRAHMBHATT, Yasmin, RIBEIRO, Kezia, UKNIS, Marc E, MULGAONKAR, Shamkant, MATHIS, A. Scott

“…The optimal regimen for prophylaxis of cytomegalovirus (CMV) disease after kidney and/or pancreas transplantation remains unclear. We compared the…”
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Gene silencing in the endocrine pancreas mediated by short-interfering RNA by Bradley, Sean P, Rastellini, Cristiana, da Costa, Marco A, Kowalik, Timothy F, Bloomenthal, Aaron B, Brown, Melissa, Cicalese, Luca, Basadonna, Giacomo P, Uknis, Marc E

“…RNA interference as mediated by short-interfering RNA (siRNA) offers a nonviral means to silence genes in tissue; however, few data exist about gene therapy…”
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Preprocedural administration of nanofiltered C1 esterase inhibitor to prevent hereditary angioedema attacks by Grant, J Andrew, White, Martha V, Li, H Henry, Fitts, David, Kalfus, Ira N, Uknis, Marc E, Lumry, William R

“…Patients with hereditary angioedema (HAE) may have attacks triggered by dental, medical, or surgical procedures. This analysis evaluated the efficacy and…”
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Nanofiltered C1 esterase inhibitor (human) for hereditary angioedema attacks in pregnant women by Baker, James W, Craig, Timothy J, Riedl, Marc A, Banerji, Aleena, Fitts, David, Kalfus, Ira N, Uknis, Marc E

“…Data are limited on hereditary angioedema (HAE) in pregnant women and the safety and efficacy of therapies for treatment and prevention of HAE attacks during…”
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Renal Allograft Failure Predictors After PAK Transplantation: Results From the New England Collaborative Association of Pancreas Programs by PAVLAKIS, Martha, KHWAJA, Khalid, MANDELBROT, Didier, HONGYING TANG, WHITING, James W, LORBER, Marc I, GAUTAM, Amitabh, JOHNSON, Scott R, UKNIS, Marc E

“…The reasons for kidney allograft failure subsequent to pancreas after kidney (PAK) are multifactorial; therefore, we examined these factors to identify a…”
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Nanofiltered C1 esterase inhibitor for treatment of laryngeal attacks in patients with hereditary angioedema by Riedl, Marc A, Lumry, William R, Li, H Henry, Craig, Timothy J, Fitts, David, Kalfus, Ira, Uknis, Marc E

“…Laryngeal edema is a life-threatening manifestation of hereditary angioedema (HAE), an autosomal-dominant disorder caused by quantitative or functional C1…”
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On the intraoperative molecular status of renal allografts after vascular reperfusion and clinical outcomes by AVIHINGSANON, Yingyos, NAILI MA, XIN XIAO ZHENG, STROM, Terry B, PAVLAKIS, Martha, CHON, W. James, UKNIS, Marc E, MONACO, Anthony P, FERRAN, Christiane, STILLMAN, Isaac, SCHACHTER, Asher D, MOTTLEY, Christina

“…Many hypothesize that subtle inflammation and immune activity detected in the intraoperative period are linked to adverse postkidney transplant clinical…”
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Gene expression profiling of the donor kidney at the time of transplantation predicts clinical outcomes 2 years after transplantation by Bodonyi-Kovacs, Gabor, Putheti, Prabhakar, Marino, Miguel, Avihingsanon, Yingyos, Uknis, Marc E, Monaco, Anthony P, Strom, Terry B, Pavlakis, Martha

“…Abstract We have previously demonstrated that biomarkers of inflammation and immune activity detected within intraoperative renal transplant allograft biopsies…”
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Prophylaxis of cytomegalovirus disease in transplant patients by Uknis, Marc E

“…A historical perspective and the epidemiology, pathogenesis, and typical patient presentation of cytomegalovirus (CMV) disease in transplant patients; the…”
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Enteric drainage of a pancreas allograft is safe for patients with celiac sprue by Akoad, Mohamed, Giraldo, Mauricio, Monaco, Anthony P, Hanto, Douglas W, Uknis, Marc E

“…Akoad M, Giraldo M, Monaco AP, Hanto DW, Uknis ME. Enteric drainage of a pancreas allograft is safe for patients with celiac sprue. Clin Transplant 2002: 16:…”
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Design of a potent novel endotoxin antagonist by Uknis, Marc E, Wasiluk, Karen R, Acton, Robert D, Klaerner, Hans G, Dahlberg, Peter S, Ilyina, Elena E, Haseman, Judith R, Gray, Beulah H, Mayo, Kevin H, Dunn, David L

“…Background. Bactericidal permeability increasing protein (BPI) binds to and neutralizes lipopolysaccharide (LPS, endotoxin). Small synthetic peptides based on…”
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Differential sensitivity to Escherichia coli infection in mice lacking tumor necrosis factor p55 or interleukin-1 p80 receptors by Acton, R D, Dahlberg, P S, Uknis, M E, Klaerner, H G, Fink, G S, Norman, J G, Dunn, D L

“…To determine the effect of targeted disruption of the cellular receptors of either tumor necrosis factor alpha (TNF-alpha) or interleukin-1 beta (IL-1 beta)…”
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Macrophages expressing a fusion protein derived from bactericidal/permeability-increasing protein and IgG are resistant to endotoxin by Dahlberg, P S, Acton, R D, Uknis, M E, Klaerner, H G, Johnston, J W, Levelle, C D, Gray, B H, Dunn, D L

“…To generate a recombinant fusion protein (FP) based on the endotoxin-binding domain of bactericidal/permeability-increasing protein (BPI) and the constant…”
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Cytomegalovirus infection and disease after solid-organ transplantation: Epidemiology, prevention, and therapy by Uknis, Marc E., Dunn, David L.

“…Disease caused by cytomegalovirus (CMV) infection remains one of the largest health concerns in clinical transplantation. CMV (transmitted to recipients before…”
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Candida albicans and Escherichia coli are synergistic pathogens during experimental microbial peritonitis by KLAERNER, H. G, UKNIS, M. E, ACTON, R. D, DAHLBERG, P. S, CARLONE-JAMBOR, C, DUNN, D. L

“…Candida albicans has been isolated with increasing frequency during intraabdominal infection; yet its role as a pathogen or copathogen remains controversial. A…”
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Candida albicansandEscherichia coliAre Synergistic Pathogens during Experimental Microbial Peritonitis by Klaerner, Hans G., Uknis, Marc E., Acton, Robert D., Dahlberg, Peter S., Carlone-Jambor, Cassandra, Dunn, David L.

“…Candida albicanshas been isolated with increasing frequency during intraabdominal infection; yet its role as a pathogen or copathogen remains controversial. A…”
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Salvage therapy of open, infected surgical wounds: a retrospective review using Techni-Care by Grubbs, B C, Statz, C L, Johnson, E M, Uknis, M E, Lee, J T, Dunn, D L

“…To determine outcome of infected surgical wounds treated with 3% para-chloro-meta-xylenol + 3% phospholipid PTC [PCMX-PL] (Techni-Care). Retrospective review…”
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