Search Results - "UKEKAWA, Ryo"
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A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness
Published in Genome research (01-10-2010)“…Animal microRNA sequences are subject to 3' nucleotide addition. Through detailed analysis of deep-sequenced short RNA data sets, we show adenylation and…”
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Fibulin‐4 as a potential extracellular vesicle marker of fibrosis in patients with cirrhosis
Published in FEBS open bio (01-08-2024)“…Chronic liver injury leads to decreased liver function and increased fibrosis. Fibrosis is not only associated with the development of portal hypertension and…”
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Aberrant localization of lamin B receptor (LBR) in cellular senescence in human cells
Published in Biochemical and biophysical research communications (13-05-2016)“…5-Bromodeoxyuridine (BrdU), a thymidine analogue, induces cellular senescence in mammalian cells. BrdU induces cellular senescence probably through the…”
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Sublethal Doses of Surfactants Induce Premature Senescence in Normal Human Skin Cells
Published in Bioscience, biotechnology, and biochemistry (2011)“…We evaluated the cytotoxicity of surfactants in human cells. Synthetic surfactants showed different cytotoxicity levels depending on their structures. The…”
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Identification of MIWI-associated Poly(A) RNAs by immunoprecipitation with an anti-MIWI monoclonal antibody
Published in BioScience Trends (01-01-2012)“…MIWI is one of the PIWI subfamily of proteins mainly expressed in mouse germ cells, and associates with pachytene piRNAs. MIWI has been thought to play an…”
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Proteasome inhibitors induce changes in chromatin structure characteristic of senescent human fibroblasts
Published in Bioscience, biotechnology, and biochemistry (01-11-2004)“…Inhibitors of proteasome induced premature senescence in normal human fibroblasts. Besides morphological alteration and expression of senescence marker genes,…”
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EphA2 on urinary extracellular vesicles as a novel biomarker for bladder cancer diagnosis and its effect on the invasiveness of bladder cancer
Published in British journal of cancer (01-10-2022)“…Background Urinary extracellular vesicles (uEVs) secreted from bladder cancer contain cancer-specific proteins that are potential diagnostic biomarkers. We…”
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Accumulation of multiple forms of lamin A with down‐regulation of FACE‐1 suppresses growth in senescent human cells
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-03-2007)“…5‐Bromodeoxyuridine (BrdU) clearly induces a senescence‐like phenomenon in every cell type. Proteome analysis revealed that lamin A and C were most highly…”
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Amplification of nuclear aldolase A in mouse cell mutants resistant to Hoechst 33342
Published in Biochemical and biophysical research communications (19-03-2004)“…5-Bromodeoxyuridine (BrdU) induces a phenomenon similar to cellular senescence in mammalian cells. AT-binding ligands such as Hoechst 33258 synergistically…”
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