Search Results - "UDAYAKUMAR, Durga"

CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition by Gadhikar, Mayur A, Zhang, Jiexin, Shen, Li, Rao, Xiayu, Wang, Jing, Zhao, Mei, Kalu, Nene N, Johnson, Faye M, Byers, Lauren A, Heymach, John, Hittelman, Walter N, Udayakumar, Durga, Pandita, Raj K, Pandita, Tej K, Pickering, Curtis R, Redwood, Abena B, Piwnica-Worms, Helen, Schlacher, Katharina, Frederick, Mitchell J, Myers, Jeffrey N

“…Checkpoint kinase inhibitors (CHKi) exhibit striking single-agent activity in certain tumors, but the mechanisms accounting for hypersensitivity are poorly…”
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Current and potential roles of immuno-PET/-SPECT in CAR T-cell therapy by Mulgaonkar, Aditi, Udayakumar, Durga, Yang, Yaxing, Harris, Shelby, Öz, Orhan K, Ramakrishnan Geethakumari, Praveen, Sun, Xiankai

“…Chimeric antigen receptor (CAR) T-cell therapies have evolved as breakthrough treatment options for the management of hematological malignancies and are also…”
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MOF Phosphorylation by ATM Regulates 53BP1-Mediated Double-Strand Break Repair Pathway Choice by Gupta, Arun, Hunt, Clayton R., Hegde, Muralidhar L., Chakraborty, Sharmistha, Udayakumar, Durga, Horikoshi, Nobuo, Singh, Mayank, Ramnarain, Deepti B., Hittelman, Walter N., Namjoshi, Sarita, Asaithamby, Aroumougame, Hazra, Tapas K., Ludwig, Thomas, Pandita, Raj K., Tyler, Jessica K., Pandita, Tej K.

“…Cell-cycle phase is a critical determinant of the choice between DNA damage repair by nonhomologous end-joining (NHEJ) or homologous recombination (HR). Here,…”
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Editorial for "Prognostic Assessment in Patients With Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System Using MRI-Based Radiomics" by Udayakumar, Durga

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Pharmacological targeting of the pseudokinase Her3 by Xie, Ting, Lim, Sang Min, Westover, Kenneth D, Dodge, Michael E, Ercan, Dalia, Ficarro, Scott B, Udayakumar, Durga, Gurbani, Deepak, Tae, Hyun Seop, Riddle, Steven M, Sim, Taebo, Marto, Jarrod A, Jänne, Pasi A, Crews, Craig M, Gray, Nathanael S

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Identification of the Polypyrimidine Tract Binding Protein-associated Splicing Factor·p54(nrb) Complex as a Candidate DNA Double-strand Break Rejoining Factor by Bladen, Catherine L., Udayakumar, Durga, Takeda, Yoshihiko, Dynan, William S.

“…The biological effects of ionizing radiation are attributable, in large part, to induction of DNA double-strand breaks. We report here the identification of a…”
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Melanoma Genetics: An Update on Risk-Associated Genes by Udayakumar, Durga, PhD, Tsao, Hensin, MD, PhD

“…The past 15 years have seen rapid advances in both our understanding of hereditary melanoma genetics and the technologies that enable scientists to make…”
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MOF Phosphorylation by ATM Regulates 53BP1-Mediated Double-Strand Break Repair Pathway Choice by Gupta, Arun, Hunt, Clayton R., Hegde, Muralidhar L., Chakraborty, Sharmistha, Udayakumar, Durga, Horikoshi, Nobuo, Singh, Mayank, Ramnarain, Deepti B., Hittelman, Walter N., Namjoshi, Sarita, Asaithamby, Aroumougame, Hazra, Tapas K., Ludwig, Thomas, Pandita, Raj K., Tyler, Jessica K., Pandita, Tej K.

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Distinct Pathways of Nonhomologous End Joining That Are Differentially Regulated by DNA-dependent Protein Kinase-mediated Phosphorylation by Udayakumar, Durga, Bladen, Catherine L., Hudson, Farlyn Z., Dynan, William S.

“…Nonhomologous end joining is the most common mechanism of DNA double-strand break repair in human cells. Here we show that nonhomologous end joining can occur…”
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Abstract 1340 Placental Transcriptomes Differ in Pregnancies Complicated by Fetal Left Ventricular Outflow Tract Obstruction and Chronic Placental Lesions by Udayakumar, Durga, Xiong, Bowen, Mir, Imran, Sharma, Kavita, Chalak, Lina D., Wang, Tao, Leon, Rachel

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Characterization of DNA binding and pairing activities associated with the native SFPQ.NONO DNA repair protein complex by Udayakumar, Durga, Dynan, William S

“…Nonhomologous end joining (NHEJ) is a major pathway for repair of DNA double-strand breaks. We have previously shown that a complex of SFPQ (PSF) and NONO…”
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Quantitative non-contrast perfusion MRI in the body using arterial spin labeling by Álvarez, María Guadalupe Mora, Madhuranthakam, Ananth J., Udayakumar, Durga

“…Arterial spin labeling (ASL) is a non-invasive magnetic resonance imaging (MRI) method that enables the assessment and the quantification of perfusion without…”
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On the application of pseudo-continuous arterial spin labeled MRI for pulmonary perfusion imaging by Greer, Joshua S, Wang, Yiming, Udayakumar, Durga, Hussain, Tarique, Madhuranthakam, Ananth J

“…To evaluate different approaches for the effective assessment of pulmonary perfusion with a pseudo-continuous arterial spin labeled (pCASL) MRI. Four different…”
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Selective BRAFV600E Inhibition Enhances T-Cell Recognition of Melanoma without Affecting Lymphocyte Function by BONI, Andrea, COGDILL, Alexandria P, TSAO, Hensin, WARGO, Jennifer A, PING DANG, UDAYAKUMAR, Durga, NJAUW, Ching-Ni Jenny, SLOSS, Callum M, FERRONE, Cristina R, FLAHERTY, Keith T, LAWRENCE, Donald P, FISHER, David E

“…Targeted therapy against the BRAF/mitogen-activated protein kinase (MAPK) pathway is a promising new therapeutic approach for the treatment of melanoma…”
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Characterization of DNA binding and pairing activities associated with the native SFPQ·NONO DNA repair protein complex by Udayakumar, Durga, Dynan, William S.

“…Nonhomologous end joining (NHEJ) is a major pathway for repair of DNA double-strand breaks. We have previously shown that a complex of SFPQ (PSF) and NONO…”
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Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine by Harshbarger, Wayne, Gondi, Sudershan, Ficarro, Scott B., Hunter, John, Udayakumar, Durga, Gurbani, Deepak, Singer, William D., Liu, Yan, Li, Lianbo, Marto, Jarrod A., Westover, Kenneth D.

“…Glutathione S-transferase pi 1 (GSTP1) is frequently overexpressed in cancerous tumors and is a putative target of the plant compound piperlongumine (PL),…”
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Pharmacological targeting of the pseudokinase Her3 by Xie, Ting, Lim, Sang Min, Westover, Kenneth D, Dodge, Michael E, Ercan, Dalia, Ficarro, Scott B, Udayakumar, Durga, Gurbani, Deepak, Tae, Hyun Seop, Riddle, Steven M, Sim, Taebo, Marto, Jarrod A, Jänne, Pasi A, Crews, Craig M, Gray, Nathanael S

“…The use of ATP competitive kinase inhibitors against the pseudokinase Her3 has been largely unsuccessful. Hydrophobic tagging of a covalent kinase inhibitor…”
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A 3D‐printed phantom for quality‐controlled reproducibility measurements of arterial spin labeled perfusion by Wang, Yiming, Greer, Joshua S., Zhou, Limin, Lin, Sheng‐Qing, Hulsey, Keith M., Udayakumar, Durga, Madhuranthakam, Ananth J.

“…Purpose To develop a portable MR perfusion phantom for quality‐controlled assessment and reproducibility of arterial spin labeled (ASL) perfusion measurement…”
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Magnetic Resonance Perfusion Imaging for Breast Cancer by Udayakumar, Durga, Madhuranthakam, Ananth J., Doğan, Başak E.

“…Breast cancer is the most frequently diagnosed cancer among women worldwide, carrying a significant socioeconomic burden. Breast cancer is a heterogeneous…”
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Single‐shot RARE with Dixon: Application to robust abdominal imaging with uniform fat and water separation at 3T by Wang, Xinzeng, Udayakumar, Durga, Xi, Yin, Rofsky, Neil M., Pedrosa, Ivan, Madhuranthakam, Ananth J.

“…Purpose To develop a true single shot turbo spin echo (SShTSE) acquisition with Dixon for robust T2‐weighted abdominal imaging with uniform fat and water…”
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