Search Results - "UCHIKAWA, M"

Molecular basis for D− Japanese: identification of novel DEL and D− alleles by Ogasawara, K., Suzuki, Y., Sasaki, K., Osabe, T., Isa, K., Tsuneyama, H., Uchikawa, M., Satake, M., Tadokoro, K.

“…Background and Objectives The occurrence of D− is approximately 0·5% in Japanese, but DEL in apparently D− individuals is relatively common compared with that…”
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Weak D alleles in Japanese: a c.960G>A silent mutation in exon 7 of the RHD gene that affects D expression by Ogasawara, K., Sasaki, K., Isa, K., Tsuneyama, H., Uchikawa, M., Satake, M., Tadokoro, K.

“…Background and Objectives The molecular basis of the weak D phenotype has been investigated for many years, and more than 80 different alleles producing weak D…”
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The KANNO blood group system by Ohto, H, Uchikawa, M, Ito, S, Wada, I, Nollet, K E, Omae, Y, Ogasawara, K, Tokunaga, K

“…The KANNO blood group system (International Society of Blood Transfusion [ISBT] 037) includes one high-prevalence antigen, KANNO1, across ethnic groups…”
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The B allele with a 5·8 kb deletion in intron 1 of the ABO gene is the major allele in Japanese individuals with Bm and A1Bm phenotypes by Ogasawara, K., Miyazaki, T., Ito, S., Yabe, R., Uchikawa, M., Enomoto, T., Yokoya, N., Hori, Y., Kumamoto, M., Watanabe, S., Satake, M.

“…Bm and A1Bm phenotypes are the most frequent ABO variants in the Japanese population. The B antigen on Bm red blood cells is only detectable by adsorption and…”
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Prevalence of RHD alleles in Japanese individuals with weak D phenotype: Identification of 20 new RHD alleles by Isa, K., Sasaki, K., Ogasawara, K., Saito, M., Tsuneyama, H., Yabe, R., Uchikawa, M., Satake, M.

“…We identified 46 different RHD alleles from 226 Japanese individuals with weak D phenotype, 26 of which had been previously described and 20 that were novel…”
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Deletion of the RUNX1 binding site in the erythroid cell-specific regulatory element of the ABO gene in two individuals with the Am phenotype by Takahashi, Y., Isa, K., Sano, R., Nakajima, T., Kubo, R., Takahashi, K., Kominato, Y., Tsuneyama, H., Ogasawara, K., Uchikawa, M.

“…Background and Objectives An erythroid cell‐specific regulatory element, referred to as the +5·8‐kb site, had been identified in the first intron of the human…”
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Presence of nucleotide substitutions in the ABO promoter in individuals with phenotypes A3 and B3 by Isa, K., Yamamuro, Y., Ogasawara, K., Yabe, R., Ogiyama, Y., Ito, S., Takahashi, Y., Kominato, Y., Sano, R., Uchikawa, M.

“…Recently, the involvement of mutation and deletion of transcription regulatory elements in the Bm, Am, A3 and B3 phenotypes has been reported. In the present…”
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Blood group B gene is barely expressed in in vitro erythroid culture of Bm-derived CD34+ cells without an erythroid cell-specific regulatory element by Sano, R., Nogawa, M., Nakajima, T., Takahashi, Y., Takahashi, K., Kubo, R., Kominato, Y., Yokohama, A., Tsukada, J., Yamao, H., Kishida, T., Ogasawara, K., Uchikawa, M.

“…Background and Objectives Previously, a weak phenotype Am or Bm was assumed to be caused by a reduction of A or B gene expression in bone marrow cells, but not…”
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Silent KEL alleles identified from Japanese individuals with the Ko phenotype by Onodera, T., Kawai, M., Obara, K., Enomoto, T., Sasaki, K., Osabe, T., Ogasawara, K., Toyoda, C., Tsuneyama, H., Uchikawa, M., Inaba, S., Satake, M.

“…Background and Objective The rare Ko phenotype lacks all 36 antigens in the Kell blood system. The molecular basis of the Ko phenotype has been investigated,…”
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Silent KEL alleles identified from Japanese individuals with the K o phenotype by Onodera, T, Kawai, M, Obara, K, Enomoto, T, Sasaki, K, Osabe, T, Ogasawara, K, Toyoda, C, Tsuneyama, H, Uchikawa, M, Inaba, S, Satake, M

“…The rare K phenotype lacks all 36 antigens in the Kell blood system. The molecular basis of the K phenotype has been investigated, and more than 40 silent KEL…”
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Presence of nucleotide substitutions in transcriptional regulatory elements such as the erythroid cell-specific enhancer-like element and the ABO promoter in individuals with phenotypes A3 and B3, respectively by Takahashi, Y., Isa, K., Sano, R., Nakajima, T., Kubo, R., Takahashi, K., Kominato, Y., Michino, J., Masuno, A., Tsuneyama, H., Ito, S., Ogasawara, K., Uchikawa, M.

“…Background and objectives An erythroid cell‐specific regulatory element, referred to as the +5.8‐kb site, has been identified in the first intron of the human…”
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A novel DO null allele with a c.268C>T (p.Gln90Stop) mutation in Japanese by Onodera, T., Tsuneyama, H., Ogasawara, K., Isa, K., Satake, M., Tadokoro, K., Uchikawa, M.

“…The Dombrock blood group system consists of two antithetical antigens, Doa (DO1) and Dob (DO2), and seven high‐prevalence antigens, Gya (DO3), Hy (DO4), Joa…”
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The B allele with a 5·8 kb deletion in intron 1 of the ABO gene is the major allele in Japanese individuals with B m and A 1 B m phenotypes by Ogasawara, K, Miyazaki, T, Ito, S, Yabe, R, Uchikawa, M, Enomoto, T, Yokoya, N, Hori, Y, Kumamoto, M, Watanabe, S, Satake, M

“…B and A B phenotypes are the most frequent ABO variants in the Japanese population. The B antigen on B red blood cells is only detectable by adsorption and…”
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A 3·0-kb deletion including an erythroid cell-specific regulatory element in intron 1 of the ABO blood group gene in an individual with the Bm phenotype by Sano, R., Kuboya, E., Nakajima, T., Takahashi, Y., Takahashi, K., Kubo, R., Kominato, Y., Takeshita, H., Yamao, H., Kishida, T., Isa, K., Ogasawara, K., Uchikawa, M.

“…We developed a sequence‐specific primer PCR (SSP‐PCR) for detection of a 5·8‐kb deletion (Bm5·8) involving an erythroid cell‐specific regulatory element in…”
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JK null alleles identified from Japanese individuals with Jk(a−b−) phenotype by Onodera, T., Sasaki, K., Tsuneyama, H., Isa, K., Ogasawara, K., Satake, M., Tadokoro, K., Uchikawa, M.

“…The Kidd blood group system consists of three common phenotypes: Jk(a+b−), Jk(a−b+) and Jk(a+b+), and one rare phenotype, Jk(a−b−). Jka/Jkb polymorphism is…”
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Application of bead array technology to simultaneous detection of human leucocyte antigen and human platelet antigen antibodies by Fujiwara, K., Shimano, K., Tanaka, H., Sekine, M., Kashiwase, K., Uchikawa, M., Satake, M., Nakajima, K.

“…Background  Detection of antibodies against human leucocyte antigens (HLA) and human platelet antigens (HPA) is crucial for patients refractory to platelet…”
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Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction by Kamachi, Y, Uchikawa, M, Collignon, J, Lovell-Badge, R, Kondoh, H

“…Activation of the first lens-specific gene of the chicken, delta 1-crystallin, is dependent on a group of lens nuclear factors, deltaEF2, interacting with the…”
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Neogenin regulates neuronal survival through DAP kinase by Fujita, Y, Taniguchi, J, Uchikawa, M, Endo, M, Hata, K, Kubo, T, Mueller, B K, Yamashita, T

“…The repulsive guidance molecule (RGM) is a membrane-bound protein that has diverse functions in the developing central nervous system. Identification of…”
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Production of human monoclonal anti-Jk3, recognising an epitope including the Jk(a) /Jk(b) polymorphic site of the Kidd glycoprotein by Toyoda, C, Suzuki, Y, Tsuneyama, H, Onodera, T, Masuno, A, Yabe, R, Ogasawara, K, Okuda, M, Nakajima, K, Uchikawa, M

“…The Kidd blood group system consists of polymorphic antigens, Jk(a) (JK1) and Jk(b) (JK2), and a high-incidence antigen, Jk3. Anti-Jk3 is often observed in…”
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A new blood group system, RHAG: three antigens resulting from amino acid substitutions in the Rh‐associated glycoprotein by Tilley, L., Green, C., Poole, J., Gaskell, A., Ridgwell, K., Burton, N. M., Uchikawa, M., Tsuneyama, H., Ogasawara, K., Akkøk, Ç. A., Daniels, G.

“…Background and Objectives  Rh‐associated glycoprotein (RhAG) is closely associated with the Rh proteins in the red cell membrane. Two high frequency antigens…”
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