Search Results - "UCHIDA, Motoyuki"

In vitro activity of AST-120 that suppresses indole signaling in Escherichia coli, which attenuates drug tolerance and virulence by Hirakawa, Hidetada, Uchida, Motoyuki, Kurabayashi, Kumiko, Nishijima, Fuyuhiko, Takita, Ayako, Tomita, Haruyoshi

“…AST-120 (Kremezin) is used to treat progressive chronic kidney disease (CKD) by adsorbing uremic toxin precursors produced by gut microbiota, such as indole…”
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A Macroporous Magnesium Oxide-Templated Carbon Adsorbs Shiga Toxins and Type III Secretory Proteins in Enterohemorrhagic Escherichia coli , Which Attenuates Virulence by Hirakawa, Hidetada, Suzue, Kazutomo, Uchida, Motoyuki, Takita, Ayako, Kamitani, Wataru, Tomita, Haruyoshi

“…Enterohemorrhagic (EHEC) is one of the most common foodborne pathogens. However, no drug that prevents the severe complications caused by this bacterium has…”
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MUC5AC protects pancreatic cancer cells from TRAIL-induced death pathways by HOSHI, HIROTAKA, SAWADA, TETSUJI, UCHIDA, MOTOYUKI, IIJIMA, HIROKO, KIMURA, KENJIRO, HIRAKAWA, KOSEI, WANIBUCHI, HIDEKI

“…We have previously reported that a specific siRNA transfected MUC5AC could knockdown MUC5AC expression and suppress in vivo tumor growth and metastasis,…”
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Adsorption of Phenazines Produced by Pseudomonas aeruginosa Using AST-120 Decreases Pyocyanin-Associated Cytotoxicity by Hirakawa, Hidetada, Takita, Ayako, Uchida, Motoyuki, Kaneko, Yuka, Kakishima, Yuto, Tanimoto, Koichi, Kamitani, Wataru, Tomita, Haruyoshi

“…AST-120 (Kremezin) is used to treat progressive chronic kidney disease by adsorbing uremic toxin precursors produced by the gut microbiota, such as indole and…”
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Administration of oral charcoal adsorbent (AST-120) suppresses low-turnover bone progression in uraemic rats by Iwasaki, Yoshiko, Yamato, Hideyuki, Nii-Kono, Tomoko, Fujieda, Ayako, Uchida, Motoyuki, Hosokawa, Atsuko, Motojima, Masaru, Fukagawa, Masafumi

“…Background. Using a rat model of renal failure with normal parathyroid hormone levels, we had demonstrated previously that bone formation decreased depending…”
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Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling by Yamauchi, Motohiro, Oka, Yasuyoshi, Yamamoto, Masashi, Niimura, Koichi, Uchida, Motoyuki, Kodama, Seiji, Watanabe, Masami, Sekine, Ichiro, Yamashita, Shunichi, Suzuki, Keiji

“…Several DNA damage checkpoint factors form nuclear foci in response to ionizing radiation (IR). Although the number of the initial foci decreases concomitantly…”
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Regulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) by bone resorptive factors in osteoblastic cells by Uchida, Motoyuki, Shima, Masaaki, Shimoaka, Takashi, Fujieda, Ayako, Obara, Kazumi, Suzuki, Hiroyuki, Nagai, Yumiko, Ikeda, Toshiyuki, Yamato, Hideyuki, Kawaguchi, Hiroshi

“…In addition to their stimulating function on osteoclastic bone resorption, bone resorptive factors may regulate proteinases and related factors in osteoblastic…”
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Uremic toxin and bone metabolism by Iwasaki, Yoshiko, Yamato, Hideyuki, Nii-Kono, Tomoko, Fujieda, Ayako, Uchida, Motoyuki, Hosokawa, Atsuko, Motojima, Masaru, Fukagawa, Masafumi

“…Patients with end-stage renal disease (ESRD) develop various kinds of abnormalities in bone and mineral metabolism, widely known as renal osteodystrophy (ROD)…”
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Functional Assessment of Two Vitamin D-responsive Elements in the Rat 25-Hydroxyvitamin D3 24-Hydroxylase Gene by Ohyama, Yoshihiko, Ozono, Keiichi, Uchida, Motoyuki, Yoshimura, Michiko, Shinki, Toshimasa, Suda, Tatsuo, Yamamoto, Osamu

“…Two vitamin D-responsive elements (VDRE-1 and VDRE-2) were recently identified in the 5′-upstream region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene at…”
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Screening of drugs that suppress Ste11 MAPKKK activation in yeast identified a c-Abl tyrosine kinase inhibitor by Kitagawa, T.(Yamaguchi Univ. (Japan)), Hashizume, Y, Murakane, T, Koga, E, Nomura, Y, Kakihara, Y, Fujieda, A, Uchida, M, Takahashi, H, Hoshida, H, Akada, R

“…The yeast MAPKKK Ste11 activates three MAP kinase pathways, including pheromone signaling, osmosensing, and pseudohyphal/invasive growth pathways. We…”
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Spatiotemporal change of rat collagenase (MMP-13) mRNA expression in the development of the rat femoral neck by Hayami, T, Endo, N, Tokunaga, K, Yamagiwa, H, Hatano, H, Uchida, M, Takahashi, H E

“…The interepiphyseal region between the greater trochanter and the capital femoral epiphysis and the medioproximal portion of the femoral neck exhibit extensive…”
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Parathyroid hormone increases the expression level of matrix metalloproteinase-13 in vivo by UCHIDA, Motoyuki, YAMATO, Hideyuki, MURAYAMA, Hisashi, FUKUMOTO, Seiji, NAGAI, Yumiko, YAMAGIWA, Hiroshi, HAYAMI, Tadashi, TOKUNAGA, Kunihiko, ENDO, Naoto, SUZUKI, Hiroyuki, OBARA, Kazumi, FUJIEDA, Ayako

“…Parathyroid hormone (PTH) increases serum calcium (Ca) by enhancing bone resorption and renal Ca reabsorption. However, detailed mechanisms of enhanced bone…”
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Correlation Between NKG2DL Expression and Antitumor Effect of Protein-bound Polysaccharide-K in Tumor-bearing Mouse Models by Konagai, Ayano, Yoshimura, Kiyoshi, Hazama, Shouichi, Yamamoto, Noboru, Aoki, Kazunori, Ueno, Tomio, Fujioka, Masaki, Iijima, Hiroko, Kato, Mariko, Uchida, Motoyuki, Wada, Tsutomu, Inoue, Moeko, Asao, Tetsuhiko, Fuse, Masanori, Wada, Satoshi, Kuramasu, Atsuo, Kamei, Ryoji, Takeda, Shigeru, Yamamoto, Shigeru, Yoshino, Shigefumi, Oka, Masaaki, Nagano, Hiroaki

“…We investigated the relationship between the expression of natural killer group 2, member D ligands (NKG2DLs) and the antitumor effects of protein-bound…”
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Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer by HOSHI, Hirotaka, SAWADA, Tetsuji, KAKEHASHI, Anna, MIN WEI, HIRAKAWA, Kosei, WANIBUCHI, Hideki, UCHIDA, Motoyuki, SAITO, Hikaru, IIJIMA, Hiroko, TODA-AGETSUMA, Mikako, WADA, Tsutomu, YAMAZOE, Sadaaki, TANAKA, Hiroaki, KIMURA, Kenjiro

“…MUC5AC, a high molecular weight glycoprotein, is overexpressed in the ductal region of human pancreatic cancer but is not detectable in the normal pancreas,…”
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Protein-bound polysaccharide-K reduces the proportion of regulatory T cells in vitro and in vivo by AOKI, RIEKO, IIJIMA, HIROKO, KATO, MARIKO, UCHIDA, MOTOYUKI, WADA, TSUTOMU, MURATA, MASATSUNE, OGAWA, KENJI, NARITAKA, YOSHIHIKO, YOSHIMATSU, KAZUHIKO

“…Regulatory T cells (Tregs) play an important role in maintaining immunological tolerance. However, this mechanism is one of the major obstacles to overcome…”
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Klotho Gene Polymorphisms Associated With Bone Density of Aged Postmenopausal Women by Kawano, Ken‐Ichi, Ogata, Naoshi, Chiano, Mathias, Molloy, Helen, Kleyn, Patrick, Spector, Tim D., Uchida, Motoyuki, Hosoi, Takayuki, Suzuki, Takao, Orimo, Hajime, Inoue, Satoshi, Nabeshima, Yoichi, Nakamura, Kozo, Kuro‐O, Makoto, Kawaguchi, Hiroshi

“…Because mice deficient in klotho gene expression exhibit multiple aging phenotypes including osteopenia, we explored the possibility that the klotho gene may…”
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Anti-protein-bound polysaccharide-K monoclonal antibody binds the active structure and neutralizes direct antitumor action of the compound by HOSHI, Hirotaka, SAITO, Hikaru, IIJIMA, Hiroko, UCHIDA, Motoyuki, WADA, Tsutomu, ITO, Gentaro, TANAKA, Hiroaki, SAWADA, Tetsuji, HIRAKAWA, Kosei

“…Protein-bound polysaccharide K (PSK) is extracted and purified from Coriolus versicolor (CM101), and is used as an anti-cancer agent. In this study, focusing…”
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Significance of phosphorylation/dephosphorylation of 46K protein(s) in regulation of superoxide anion production in intact guinea pig polymorphonuclear leukocytes by Ohtsuka, T, Ozawa, M, Okamoto, T, Uchida, M, Okamura, N, Ishibashi, S

“…Superoxide anion (O2-) production stimulated by concanavalin A (Con A) in guinea pig polymorphonuclear leukocytes (PMNL) was suppressed by addition of…”
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Transcriptional Induction of Matrix Metalloproteinase‐13 (Collagenase‐3) by 1α,25‐Dihydroxyvitamin D3 in Mouse Osteoblastic MC3T3‐E1 Cells by Uchida, Motoyuki, Shima, Masaaki, Chikazu, Daichi, Fujieda, Ayako, Obara, Kazumi, Suzuki, Hiroyuki, Nagai, Yumiko, Yamato, Hideyuki, Kawaguchi, Hiroshi

“…The removal of unmineralized matrix from the bone surface is essential for the initiation of osteoclastic bone resorption because osteoclasts cannot attach to…”
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Identification of a vitamin D-responsive element in the 5'-flanking region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene by OHYAMA, Y, OZONO, K, UCHIDA, M, SHINKI, T, KATO, S, SUDA, T, YAMAMOTO, O, NOSHIRO, M, KATO, Y

“…The 5'-flanking region of the rat vitamin D3 24-hydroxylase (P450cc24) gene was examined and a vitamin D-responsive element (VDRE) responsible for the 1…”
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