Search Results - "UCHIDA, ITSUO"

Synthesis and Structure−Activity Relationships of 5,6,7,8-Tetrahydro-4H-thieno[3,2-b]azepine Derivatives:  Novel Arginine Vasopressin Antagonists by Cho, Hidetsura, Murakami, Kengo, Nakanishi, Hiroyuki, Fujisawa, Akitaka, Isoshima, Hirotaka, Niwa, Misako, Hayakawa, Kazuhide, Hase, Yasunori, Uchida, Itsuo, Watanabe, Hidenori, Wakitani, Korekiyo, Aisaka, Kazuo

“…A variety of novel heterocyclic compounds having thienoazepine, pyrroloazepine, furoazepine, and thienodiazepine skeletons were synthesized, most of which…”
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A Practical Synthesis of Nelfinavir, an HIV-Protease Inhibitor, Using a Novel Chiral C4 Building Block:  (5R,6S)-2,2-Dimethyl-5-hydroxy-1,3-dioxepan-6-ylammonium Acetate by Inaba, Takashi, Birchler, Angela G, Yamada, Yasuki, Sagawa, Shoichi, Yokota, Katsuyuki, Ando, Koji, Uchida, Itsuo

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Regioselective Synthesis of Several Heterocyclic Fused Azepines Using Diisobutylaluminum Hydride by Cho, Hidetsura, Murakami, Kengo, Nakanishi, Hiroyuki, Isoshima, Hirotaka, Hayakawa, Kazuhide, Uchida, Itsuo

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Structure of FR 900482, a novel antitumor antibiotic from a Streptomyces by Uchida, Itsuo, Takase, Shigehiro, Kayakiri, Hiroshi, Kiyoto, Sumio, Hashimoto, Masashi, Tada, Toshiji, Koda, Shigetaka, Morimoto, Yukiyoshi

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Stabilized Analogs of Thymopentin. 1. 4,5-Ketomethylene Pseudopeptides by DeGraw, Joseph I, Almquist, Ronald G, Hiebert, Charles K, Colwell, William T, Crase, Jac, Hayano, Takeshi, Judd, Amrit K, Dousman, Linda, Smith, R. Lane, Waud, William R, Uchida, Itsuo

“…The pentapeptide, thymopentin (Arg-Lys-Asp-Val-Tyr) is known for its activity as an immunomodulating drug, but with limited half-life in plasma. In this first…”
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Synthesis of Novel 5,6,7,8-Tetrahydro-4H-thieno[2,3-b][1,4]diazepine Derivatives by Cho, Hidetsura, Murakami, Kengo, Fujisawa, Akitaka, Niwa, Misako, Nakanishi, Hiroyuki, Uchida, Itsuo

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Stabilized Analogs of Thymopentin. 2. 1,2- and 3,4-Ketomethylene Pseudopeptides by DeGraw, Joseph I, Almquist, Ronald G, Hiebert, Charles K, Judd, Amrit K, Dousman, Linda, Smith, R. Lane, Waud, William R, Uchida, Itsuo

“…In this second paper in a series of three studies of stable analogs of thymopentin (Arg-Lys-Asp-Val-Tyr), the synthesis of analogs stablized at peptide bonds…”
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Novel Renin Inhibitors Containing (2S, 3S, 5S)-2-Amino-1-cyclohexyl-6-methyl-3, 5-heptanediol Fragment as a Transition-state Mimic at the P1-P1' Cleavage Site by YAMADA, Yasuki, ANDO, Koji, IKEMOTO, Yukishige, TADA, Hiroki, SHIRAKAWA, Eiji, INAGAKI, Eiji, SHIBATA, Saizo, NAKAMURA, Ikuro, HAYASHI, Yoshiharu, IKEGAMI, Kiyoteru, UCHIDA, Itsuo

“…A series of renin inhibitors containing the (2S, 3S, 5S)-2-amino-1-cyclohexyl-6-methyl-3, 5-heptanediol (2-amino-3, 5-anti-diol) fragment as a novel…”
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4-Aminoquinolines:  Novel Nociceptin Antagonists with Analgesic Activity by Shinkai, Hisashi, Ito, Takao, Iida, Tetsuya, Kitao, Yuki, Yamada, Hideki, Uchida, Itsuo

“…Small-molecule nociceptin antagonists were synthesized to examine their therapeutic potential. After a 4-aminoquinoline derivative was found to bind with the…”
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Structure of WS-43708A, a novel cyclic peptide antibiotic by Uchida, Itsuo, Ezaki, Masami, Shigematsu, Nobuharu, Hashimoto, Masashi

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Structure and Synthesis of Nectrisine, a New Immunomodulator Isolated from a Fungus by KAYAKIRI, Hiroshi, NAKAMURA, Katsuya, TAKASE, Shigehiro, SETOI, Hiroyuki, UCHIDA, Itsuo, TERANO, Hiroshi, HASHIMOTO, Masashi, TADA, Tosiji, KODA, Shigetaka

“…The structure of a novel immunomodulator, nectrisine (1), has been elucidated on the basis of chemical and spectroscopic evidence. Its absolute stereochemistry…”
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Biphenomycins A and B, novel peptide antibiotics. II. Structural elucidation of biphenomycins A and B by Uchida, I, Shigematsu, N, Ezaki, M, Hashimoto, M, Aoki, H, Imanaka, H

“…The structures of biphenomycins A and B, novel peptide antibiotics produced by a strain of Streptomyces, have been established as 1 and 2, respectively, on the…”
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Studies of Platelet Activating Factor (PAF) Antagonists from Microbial Products. I. : Bisdethiobis(methylthio)gliotoxin and Its Derivatives by OKAMOTO, MASANORI, YOSHIDA, KEIZO, UCHIDA, ITSUO, NISHIKAWA, MOTOAKI, KOHSAKA, MASANOBU, AOKI, HATSUO

“…A platelet activating factor (PAF) antagonist, designated as FR-49175, was isolated from fermentation products of Penicillium terlikowskii and identified as…”
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Bis(2-(Acylamino)phenyl) Disulfides, 2-(Acylamino)benzenethiols, and S-(2-(Acylamino)phenyl) Alkanethioates as Novel Inhibitors of Cholesteryl Ester Transfer Protein by Shinkai, Hisashi, Maeda, Kimiya, Yamasaki, Takahiro, Okamoto, Hiroshi, Uchida, Itsuo

“…A series of bis(2-(acylamino)phenyl) disulfides, 2-(acylamino)benzenethiols, S-(2-(acylamino)phenyl) alkanethioates, and related compounds were synthesized,…”
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Studies on WF-3681, a novel aldose reductase inhibitor. II. Structure determination and synthesis by Namiki, T, Nishikawa, M, Itoh, Y, Uchida, I, Hashimoto, M

“…The structure of WF-3681, a novel aldose reductase inhibitor produced by Chaetomella raphigera Swift No. 3681, was deduced to be 1 on the basis of its…”
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Structure of FR900452, a novel platelet-activating factor inhibitor from a Streptomyces by Takase, Shigehiro, Shigematsu, Nobuharu, Shima, Ichiro, Uchida, Itsuo, Hashimoto, Masashi, Tada, Toshiji, Koda, Shigetaka, Morimoto, Yukiyoshi

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A new antitumor complex, WF-1360, WF-1360A, B, C, D, E and F by Kiyoto, S, Kawai, Y, Kawakita, T, Kino, E, Okuhara, M, Uchida, I, Tanaka, H, Hashimoto, M, Terano, H, Kohsaka, M

“…A complex of the new antitumor antibiotics (WF-1360, WF-1360A, B, C, D, E and F) was produced by Rhizopus sp. No. F-1360. Structural studies of these compounds…”
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Studies on new dehydropeptidase inhibitors. II. Structural elucidation and synthesis of WS1358A1 and B1 by Takase, S, Uchida, I, Hashimoto, S, Tanaka, H, Hashimoto, M

“…The structures of WS1358A1 and B1, new dehydropeptidase inhibitors isolated from Streptomyces parvulus subsp. tochigiensis No. 1358, have been established to…”
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Isoxazolidine-3,5-dione and Noncyclic 1,3-Dicarbonyl Compounds as Hypoglycemic Agents by Shinkai, Hisashi, Onogi, Syoji, Tanaka, Masahiro, Shibata, Tsutomu, Iwao, Megumi, Wakitani, Korekiyo, Uchida, Itsuo

“…Isoxazolidine-3,5-dione 2 (JTT-501), one of the cyclic malonic acid derivatives, was found to decrease blood glucose at an oral dose of 38 mg/kg/day in KKAy…”
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Studies on new dehydropeptidase inhibitors. IV. Chemical transformation of WS1358 compounds and an improved synthesis of WS1358A1 by Uchida, I, Hashimoto, S, Iwamoto, T, Takase, S, Hashimoto, M

“…The structures of compounds 3 (and 4) and 5 (and 6) derived from the natural products WS1358A1 (1) (and B1 (2)) have been determined by their spectroscopic…”
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