Search Results - "Ułaszewski, Stanisław"

Yeast Genome Screening and Methods for the Discovery of Metabolic Pathways Involved in a Phenotypic Response to Anticancer Agents by Cal, Magdalena, Matyjaszczyk, Irwin, Ułaszewski, Stanisław

“…The dramatic increase of cancer in the world drives the search for a new generation of drugs useful in effective and safe chemotherapy. In the postgenomic era…”
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The Cryptococcus neoformans monocarboxylate transporter Jen4 is responsible for increased 3-bromopyruvate sensitivity by Niedźwiecka, Katarzyna, Ribas, David, Casal, Margarida, Ułaszewski, Stanisław

“…ABSTRACT In the last decades, 3-bromopyruvate (3BP) has been intensively studied as a promising anticancer and antimicrobial agent. The transport of this drug…”
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3‐Bromopyruvate as a potent anticancer therapy in honor and memory of the late Professor André Goffeau by Ko, Young H., Niedźwiecka, Katarzyna, Casal, Margarida, Pedersen, Peter L., Ułaszewski, Stanisław

“…3‐Bromopyruvate (3BP) is a small, highly reactive molecule formed by bromination of pyruvate. In the year 2000, the antitumor properties of 3BP were…”
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Vmr 1p is a novel vacuolar multidrug resistance ABC transporter in Saccharomyces cerevisiae by Wawrzycka, Donata, Sobczak, Iwona, Bartosz, Grzegorz, Bocer, Tomasz, Ułaszewski, Stanisław, Goffeau, André

“…The Saccharomyces cerevisiae Yhl035p/Vmr1p is an ABC transporter of the MRP subfamily that is conserved in all post Whole Genome Duplication species. The…”
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Butyltin(IV) 5-sulfosalicylates: Structural characterization and their cytostatic activity by Pruchnik, Hanna, Latocha, Małgorzata, Zielińska, Aleksandra, Ułaszewski, Stanisław, Pruchnik, Florian P.

“…Tributyltin and dibutyltin 5-sulfosalicylates showing very high cytotoxic activity against tumor cells have been characterized using spectroscopic methods and…”
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Transport of 3-bromopyruvate across the human erythrocyte membrane by Sadowska-Bartosz, Izabela, Soszyński, Mirosław, Ułaszewski, Stanisław, Ko, Young, Bartosz, Grzegorz

“…3-Bromopyruvic acid (3-BP) is a promising anticancer compound because it is a strong inhibitor of glycolytic enzymes, especially glyceraldehyde 3-phosphate…”
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Properties of η5-pentamethylcyclopentadienyl rhodium(III) and iridium(III) complexes with quinolin-8-ol and their cytostatic activity by Śliwińska, Urszula, Pruchnik, Florian P., Ułaszewski, Stanisław, Latocha, Małgorzata, Nawrocka-Musiał, Dominika

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The Saccharomyces cerevisiae ACR3 Gene Encodes a Putative Membrane Protein Involved in Arsenite Transport by Wysocki, Robert, Bobrowicz, Piotr, Ułaszewski, Stanisław

“…The cluster of three genes, ACR1,ACR2, and ACR3, previously was shown to confer arsenical resistance in Saccharomyces cerevisiae. The overexpression of ACR3…”
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Dinuclear Rh(II) complexes with one polypyridyl ligand, structure, properties and antitumor activity by Ćwikowska, Magdalena, Pruchnik, Florian P., Starosta, Radosław, Chojnacki, Henryk, Wilczok, Adam, Ułaszewski, Stanisław

“…Rhodium(II) complexes [Rh 2(μ-OAc) 3(N–N)(H 2O) 3]PF 6 and [Rh 2(μ-OAc) 3(OAc)(N–N)] (N–N = polypyridyl) have been characterized using NMR, IR and UV–Vis…”
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The physiological and morphological phenotype of a yeast mutant resistant to the quaternary ammonium salt N-(dodecyloxycarboxymethyl)-N,N,N-trimethyl ammonium chloride by Obłąk, Ewa, Gamian, Andrzej, Adamski, Ryszard, Ułaszewski, Stanisław

“…We investigated the action of the quaternary ammonium salt (QAS) called IM (N-(dodecyloxycarboxymethyl)-N,N,N-trimethyl ammonium chloride) on Saccharomyces…”
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Synthesis, structure and antitumor activity of [RhCl 3(N–N)(DMSO)] polypyridyl complexes by Śliwińska, Urszula, Pruchnik, Florian P., Pelińska, Irena, Ułaszewski, Stanisław, Wilczok, Adam, Zajdel, Alicja

“…The [RhCl 3(N–N)(DMSO)] complexes, the N–N being 2,2′-bipyridine ( 1), 1,10-phenanthroline ( 2), 4,7-diphenyl-1,10-phenanthroline ( 3),…”
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Rapid and easy detection of the five most common mutations in BRCA1 and BRCA2 genes in the Polish population using CAPS and ACRS-PCR methods by Dąbrowski, Adam, Ułaszewski, Stanisław, Niedźwiecka, Katarzyna

“…In this publication we present a fast method of diagnosing the most common polymorphisms of BRCA1 and BRCA2 genes in Poland – C61G [c.300T>G], C64R [c.190T>C],…”
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The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate by Lis, Paweł, Dyląg, Mariusz, Niedźwiecka, Katarzyna, Ko, Young H, Pedersen, Peter L, Goffeau, Andre, Ułaszewski, Stanisław

“…This review summarizes the current state of knowledge about the metabolism of cancer cells, especially with respect to the "Warburg" and "Crabtree" effects…”
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Mitochondrial Function Are Disturbed in the Presence of the Anticancer Drug, 3-Bromopyruvate by Cal, Magdalena, Matyjaszczyk, Irwin, Filik, Karolina, Ogórek, Rafał, Ko, Young, Ułaszewski, Stanisław

“…3-bromopuryvate (3-BP) is a compound with unique antitumor activity. It has a selective action against tumor cells that exhibit the Warburg effect. It has been…”
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Isolation of Three Contiguous Genes,ACR1,ACR2 andACR3, Involved in Resistance to Arsenic Compounds in the YeastSaccharomyces cerevisiae by Bobrowicz, Piotr, Wysocki, Robert, Owsianik, Grzegorz, Goffeau, André, Ułaszewski, Stanisław

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The Anticancer Drug 3-Bromopyruvate Induces DNA Damage Potentially Through Reactive Oxygen Species in Yeast and in Human Cancer Cells by Cal, Magdalena, Matyjaszczyk, Irwin, Litwin, Ireneusz, Augustyniak, Daria, Ogórek, Rafał, Ko, Young, Ułaszewski, Stanisław

“…3-bromopyruvate (3-BP) is a small molecule with anticancer and antimicrobial activities. 3-BP is taken up selectively by cancer cells' mono-carboxylate…”
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Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma by Niedźwiecka, Katarzyna, Dyląg, Mariusz, Augustyniak, Daria, Majkowska-Skrobek, Grażyna, Cal-Bąkowska, Magdalena, Ko, Young H, Pedersen, Peter L, Goffeau, Andre, Ułaszewski, Stanisław

“…In different fungal and algal species, the intracellular concentration of reduced glutathione (GSH) correlates closely with their susceptibility to killing by…”
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3-Bromopyruvate: A novel antifungal agent against the human pathogen Cryptococcus neoformans by Dyląg, Mariusz, Lis, Paweł, Niedźwiecka, Katarzyna, Ko, Young H., Pedersen, Peter L., Goffeau, Andre, Ułaszewski, Stanisław

“…•We examined the antifungal activity of 3-bromopyruvic acid (3-BP).•3-BP could be a novel antifungal agent against Cryptococcus neoformans.•3-BP acts on C…”
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Vmr 1p is a novel vacuolar multidrug resistance ABC transporter in Saccharomyces cerevisiae: Vacuolar mutidrug-resistant Vmr1p by Wawrzycka, Donata, Sobczak, Iwona, Bartosz, Grzegorz, Bocer, Tomasz, Ułaszewski, Stanisław, Goffeau, André

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Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate by Lis, Paweł, Jurkiewicz, Paweł, Cal-Bąkowska, Magdalena, Ko, Young H, Pedersen, Peter L, Goffeau, Andre, Ułaszewski, Stanisław

“…In this study the detailed characteristic of the anti-cancer agent 3-bromopyruvate (3-BP) activity in the yeast Saccharomyces cerevisiae model is described,…”
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