The Pathology of Diphtheria

Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in the pharynx with pseudomembrane formation or, less commonly, in the stomach or lungs; systemic dissemination of toxin then invokes lesions in...

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Bibliographic Details
Published in:	The Journal of infectious diseases Vol. 181; no. Supplement-1; pp. S116 - S120
Main Authors:	Hadfield, Ted L., McEvoy, Peter, Polotsky, Yury, Tzinserling, Vsevolod A., Yakovlev, Alexey A.
Format:	Journal Article
Language:	English
Published:	United States The University of Chicago Press 01-02-2000 University of Chicago Press Oxford University Press
Subjects:	Adult Child Corynebacterium diphtheriae Corynebacterium diphtheriae - isolation & purification Diphtheria Diphtheria - epidemiology Diphtheria - microbiology Diphtheria - pathology Disease Outbreaks Epidemiology Humans Infections Infectious diseases Lesions Myocardium Necrosis Pathology Toxins USSR - epidemiology USSR
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Summary:	Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in the pharynx with pseudomembrane formation or, less commonly, in the stomach or lungs; systemic dissemination of toxin then invokes lesions in distant organs. Acute disease of the upper respiratory tract usually involves one or more of the following: tonsillar zones, larynx, soft palate, uvula, and nasal cavities. A recent epidemic in Russia emphasized the role of vaccination in reducing disease in children and adults.
Bibliography:	ark:/67375/HXZ-B68962FL-5 istex:27196452D7D51617AAC0B3534A8AFEE59629199C ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0022-1899 1537-6613
DOI:	10.1086/315551