Search Results - "Tzeng, Alice"

Human breast microbiome correlates with prognostic features and immunological signatures in breast cancer by Tzeng, Alice, Sangwan, Naseer, Jia, Margaret, Liu, Chin-Chih, Keslar, Karen S, Downs-Kelly, Erinn, Fairchild, Robert L, Al-Hilli, Zahraa, Grobmyer, Stephen R, Eng, Charis

“…Currently, over half of breast cancer cases are unrelated to known risk factors, highlighting the importance of discovering other cancer-promoting factors…”
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Antigen specificity can be irrelevant to immunocytokine efficacy and biodistribution by Tzeng, Alice, Kwan, Byron H., Opel, Cary F., Navaratna, Tejas, Wittrup, K. Dane

“…Cytokine therapy can activate potent, sustained antitumor responses, but collateral toxicity often limits dosages. Although antibody–cytokine fusions…”
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The intestinal flora is required to support antibody responses to systemic immunization in infant and germ free mice by Lamousé-Smith, Esi S, Tzeng, Alice, Starnbach, Michael N

“…The presence of a complex and diverse intestinal flora is functionally important for regulating intestinal mucosal immune responses. However, the extent to…”
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Treatment-free survival after discontinuation of immune checkpoint inhibitors in metastatic renal cell carcinoma: a systematic review and meta-analysis by Tzeng, Alice, Tzeng, Tony H, Ornstein, Moshe C

“…While immune checkpoint inhibitors (ICI) can lead to sustained responses in metastatic renal cell carcinoma (mRCC), the optimal duration of therapy remains…”
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Prevention of pulmonary morbidity for patients with neuromuscular disease by Tzeng, A C, Bach, J R

“…To evaluate the effects of a respiratory muscle aid protocol on hospitalization rates for respiratory complications of neuromuscular disease. A retrospective…”
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Fecal microbiota of adolescent and young adult cancer survivors and metabolic syndrome: an exploratory study by Rotz, Seth J., Sangwan, Naseer, Nagy, Matthew, Tzeng, Alice, Jia, Margaret, Moncaliano, Maria, Majhail, Navneet S., Eng, Charis

“…Metabolic syndrome and obesity occur commonly in long-term pediatric cancer survivors. The intestinal microbiome is associated with metabolic syndrome and…”
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Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models by Rothschilds, Adrienne, Tzeng, Alice, Mehta, Naveen K., Moynihan, Kelly D., Irvine, Darrell J., Wittrup, K. Dane

“…In combination cancer immunotherapies, consideration should be given to designing treatment schedules that harmonize with the immune system's natural timing…”
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Immunological Correlates of Response to Immune Checkpoint Inhibitors in Metastatic Urothelial Carcinoma by Tzeng, Alice, Diaz-Montero, C. Marcela, Rayman, Patricia A., Kim, Jin S., Pavicic, Paul G., Finke, James H., Barata, Pedro C., Lamenza, Marcelo, Devonshire, Sarah, Schach, Kim, Emamekhoo, Hamid, Ernstoff, Marc S., Hoimes, Christopher J., Rini, Brian I., Garcia, Jorge A., Gilligan, Timothy D., Ornstein, Moshe C., Grivas, Petros

“…Background The identification of prognostic and/or predictive biomarkers for response to immune checkpoint inhibitors (ICI) could help guide treatment…”
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Pneumonitis in Patients Receiving Thoracic Radiotherapy and Osimertinib: A Multi-Institutional Study by Banla, Leou Ismael, Tzeng, Alice, Baillieul, John P., Kandekhar, Melin J., Fitzgerald, Kelly J., LoPiccolo, Jaclyn, Poitras, Holly A., Soto, Dan E., Rotow, Julia K., Singer, Lisa, Willers, Henning, Kozono, David E., Janne, Pasi A., Mak, Raymond H., Piotrowska, Zofia, Keane, Florence K., Kann, Benjamin H.

“…Thoracic radiotherapy (TRT) is increasingly used in patients receiving osimertinib for advanced NSCLC, and the risk of pneumonitis is not established. We…”
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The Role of Patient Activation in Achieving Better Outcomes and Cost-Effectiveness in Patient Care by Tzeng, Alice, BA, Tzeng, Tony H., BS, Vasdev, Sonia, MD, MPH, MPA, Grindy, Anna, BA, Saleh, Jamal K., BS, Saleh, Khaled J., BSc, MD, MSc, FRCS(C), MHCM

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Neuromuscular ventilatory insufficiency : Effect of home mechanical ventilator use v oxygen therapy on pneumonia and hospitalization rates by BACH, J. R, RAJARAMAN, R, BALLANGER, F, TZENG, A. C, ISHIKAWA, Y, KULESSA, R, BANSAL, T

“…The purpose of this study was to determine rates of pneumonia and hospitalization for patients receiving oxygen therapy, patients having indwelling…”
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Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses by Moynihan, Kelly D, Opel, Cary F, Szeto, Gregory L, Tzeng, Alice, Zhu, Eric F, Engreitz, Jesse M, Williams, Robert T, Rakhra, Kavya, Zhang, Michael H, Rothschilds, Adrienne M, Kumari, Sudha, Kelly, Ryan L, Kwan, Byron H, Abraham, Wuhbet, Hu, Kevin, Mehta, Naveen K, Kauke, Monique J, Suh, Heikyung, Cochran, Jennifer R, Lauffenburger, Douglas A, Wittrup, K Dane, Irvine, Darrell J

“…An immunotherapy consisting of a tumor-antigen targeting antibody, PD-1 blocking antibody, extended half-life recombinant IL-2 and a lymph-node-targeted T cell…”
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Treating periprosthetic joint infections as biofilms: key diagnosis and management strategies by Tzeng, Alice, Tzeng, Tony H, Vasdev, Sonia, Korth, Kyle, Healey, Travis, Parvizi, Javad, Saleh, Khaled J

“…Abstract Considerable evidence suggests that microbial biofilms play an important role in periprosthetic joint infection (PJI) pathogenesis. Compared to…”
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A study of thyrotropin-releasing hormone for the treatment of spinal muscular atrophy: A preliminary report by TZENG, Alice C, JENFU CHENG, FRYCZYNSKI, Hillary, NIRANJAN, Vis, STITIK, Todd, SIAL, Ashu, TAKEUCHI, Yoshihiro, FOYE, Patrick, DEPRINCE, Melissa, BACH, John R

“…To determine whether thyrotropin-releasing hormone (TRH) can increase muscle strength in children with spinal muscular atrophy types 2 and 3. A randomized,…”
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Immunological correlates of response and immune-mediated toxicity in checkpoint inhibitor (ICI)-treated metastatic urothelial carcinoma (mUC) patients (pts) by Nizam, Amanda, Tzeng, Alice, Wei, Wei, Rayman, Patricia A., Pavicic, Paul G., Makarov, Vladimir, Juric, Ivan, Alban, Tyler, Swaidani, Shadi, Sheng, Iris Yeong-Fung, Gilligan, Timothy D., Gupta, Shilpa, Diaz-Montero, C. Marcela, Ornstein, Moshe Chaim

“…Abstract only 526 Background: Myeloid derived suppressors cells (MDSC) are immune cells that create an immunosuppressive microenvironment. Increased expression…”
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Interplay Between Class II HLA Genotypes and the Microbiome and Immune Phenotypes in Individuals With PTEN Hamartoma Tumor Syndrome by Jia, Margaret, Sangwan, Naseer, Tzeng, Alice, Eng, Charis

“…We evaluate potential contributors to the development of autoimmunity and other phenotypes consistent with immune dysregulation in individuals with germline…”
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Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses by Kwan, Byron H, Zhu, Eric F, Tzeng, Alice, Sugito, Harun R, Eltahir, Ahmed A, Ma, Botong, Delaney, Mary K, Murphy, Patrick A, Kauke, Monique J, Angelini, Alessandro, Momin, Noor, Mehta, Naveen K, Maragh, Alecia M, Hynes, Richard O, Dranoff, Glenn, Cochran, Jennifer R, Wittrup, K Dane

“…Certain RGD-binding integrins are required for cell adhesion, migration, and proliferation and are overexpressed in most tumors, making them attractive…”
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Safety and Efficacy Outcomes in Immune Checkpoint Inhibitor-Treated Patients With Metastatic Urothelial Carcinoma Requiring Treatment Interruption or Discontinuation Due to Immune-Related Adverse Events by Nizam, Amanda, Rader, Ryan K., Tzeng, Alice, Wei, Wei, Sheng, Iris Yeong-Fung, Martin, Allison, Wee, Christopher E., Gilligan, Timothy D., Gupta, Shilpa, Ornstein, Moshe C.

“…As most patients with metastatic urothelial carcinoma (mUC) will be treated with immune checkpoint inhibitors (ICI), familiarity with their associated…”
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Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy by Tzeng, Alice, Kauke, Monique J., Zhu, Eric F., Moynihan, Kelly D., Opel, Cary F., Yang, Nicole J., Mehta, Naveen, Kelly, Ryan L., Szeto, Gregory L., Overwijk, Willem W., Irvine, Darrell J., Wittrup, K. Dane

“…Numerous synergistic cancer immunotherapy combinations have been identified, but the effects of relative dose timing are rarely considered. In established…”
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Immunological correlates of response to immune checkpoint inhibitors (ICI) in metastatic urothelial carcinoma (mUC) patients (pts) by Tzeng, Alice, Diaz-Montero, C. Marcela, Rayman, Patricia A., Kim, Jin Sub, Pavicic, Paul G, Finke, James, Barata, Pedro C., Lamenza, Marcelo, Devonshire, Sarah, Schach, Kim, Emamekhoo, Hamid, Ernstoff, Marc S., Hoimes, Christopher J., Rini, Brian I., Garcia, Jorge A., Gilligan, Timothy D., Ornstein, Moshe Chaim, Grivas, Petros

“…Abstract only 454 Background: Identification of biomarkers predictive of response to ICI could help guide treatment (tx) decisions. We assessed the correlation…”
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