Spectral and luminescent properties of sensitizers based on psoralen substitutes

Spectral and luminescent properties of sensitizers based on psoralen substitutes

Psoralens (furocoumarines) are photosensitizers of vegetative origin increasing the sensitivity of biological objects to near-ultraviolet radiation (UV-A, 320–400 nm). In the present work, the influence of substitution on the energy level diagram is considered for the first element of the series-pso...

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Bibliographic Details
Published in:Russian physics journal Vol. 51; no. 7; pp. 706 - 713
Main Authors: Bryantseva, N. G., Sokolova, I. V., Svetlichnyi, V. A., Tyshkylova, A. V., Garazd, Ya. L., Khilya, V. P.
Format: Journal Article
Language:English
Published: Boston Springer US 01-07-2008
Subjects:
Condensed Matter Physics
Hadrons
Heavy Ions
Lasers
Mathematical and Computational Physics
Nuclear Physics
Optical Devices
Optics
Optics and Spectroscopy
Photonics
Physics
Physics and Astronomy
Theoretical
Energy Level Diagram
Psoralen
Photophysical Process
Oscillator Force
XeCl Laser
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Summary:Psoralens (furocoumarines) are photosensitizers of vegetative origin increasing the sensitivity of biological objects to near-ultraviolet radiation (UV-A, 320–400 nm). In the present work, the influence of substitution on the energy level diagram is considered for the first element of the series-psoralen. The absorption and fluorescence spectra are investigated with the use of an SM-2203 spectrofluorimeter, and theoretical calculations are carried out. In addition, the results obtained are compared with the calculated and experimental results of other authors. The employed method of intermediate neglect of differential overlap (INDO) yields such parameters as an oscillator force, nature and energy of the transition, positions of triplets and singlets, etc. The geometry is optimized by the semi-empirical PM3 method of the program Hyperchem 6.03. A comparison of the calculated results for the examined compounds demonstrates that after the substitution, the absorption spectra are shifted toward the red range. The lower excited singlet of the 21,22-dimethyl-10,11-cyclohexylpsoralen compound lies higher than that of psoralen and 10,11-phenyl-21,22-cyclohexylpsoralen; it is located at 332 nm. The absorption spectra from the excited states undergo a bathochromic shift after the substitution. The most intensive T-T absorption bands are also indicated in this work.
ISSN:1064-8887
1573-9228
DOI:10.1007/s11182-008-9099-x