Search Results - "Tyrcha, Urszula"

IGF2 Peptide-Based LYTACs for Targeted Degradation of Extracellular and Transmembrane Proteins by Mikitiuk, Michał, Barczyński, Jan, Bielski, Przemysław, Arciniega, Marcelino, Tyrcha, Urszula, Hec, Aleksandra, Lipińska, Andrea D, Rychłowski, Michał, Holak, Tad A, Sitar, Tomasz

“…Lysosome-targeting chimeras (LYTACs) have recently been developed to facilitate the lysosomal degradation of specific extracellular and transmembrane molecular…”
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N-methylmorpholine incorporation into the structure of biphenyl leads to the bioactive inhibitor of PD-1/PD-L1 interaction by Zaber, Julia, Skalniak, Lukasz, Gudz, Ganna P., Hec-Gałązka, Aleksandra, Zarnik, Magdalena, Tyrcha, Urszula, Stec, Malgorzata, Siedlar, Maciej, Holak, Tad A., Sitar, Tomasz, Muszak, Damian

“…[Display omitted] •Utility of N-methylmorpholine derivatives as inhibitors of PD-L1 protein.•Optimal elongation path determination of N-methylmorpholine in the…”
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Nonsymmetrically Substituted 1,1′-Biphenyl-Based Small Molecule Inhibitors of the PD-1/PD-L1 Interaction by Hec-Gałązka, Aleksandra, Tyrcha, Urszula, Barczyński, Jan, Bielski, Przemyslaw, Mikitiuk, Michał, Gudz, Ganna P., Kitel, Radosław, Musielak, Bogdan, Plewka, Jacek, Sitar, Tomasz, Holak, Tad A.

“…Therapeutic antibodies directed against either programmed cell death-1 protein (PD-1) or its ligand PD-L1 have demonstrated efficacy in the treatment of…”
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