Association of lipoprotein lipase gene with coronary heart disease in Sudanese population

Association of lipoprotein lipase gene with coronary heart disease in Sudanese population

Abstract Cardiovascular disease is stabilizing in high-income countries and has continued to rise in low-to-middle-income countries. Association of lipid profile with lipoprotein lipase gene was studied in case and control subject. The family history, hypertension, diabetes mellitus, smoking and alc...

Full description

Saved in:
Bibliographic Details
Published in:Journal of epidemiology and global health Vol. 5; no. 4; pp. 405 - 407
Main Authors: Abdel Hamid, Muzamil M, Ahmed, Safa, Salah, Awatif, Tyrab, Etayeb M.A, Yahia, Lemya M, Elbashir, Elbagire A, Musa, Hassan H
Format: Journal Article
Language:English
Published: Dordrecht Elsevier Ltd 01-12-2015
Springer Netherlands
Springer Nature B.V
Atlantis Press
Springer
Subjects:
Age
Cardiovascular disease
Cardiovascular diseases
Case-Control Studies
Coronary artery disease
Coronary Disease - epidemiology
Coronary Disease - genetics
Coronary heart disease
Diabetes mellitus
Female
Fish oils
Gene frequency
Gene polymorphism
Heart diseases
Humans
Internal Medicine
Lipase
Lipid profile
Lipids - blood
Lipoprotein lipase
Lipoprotein Lipase - genetics
Lipoproteins
Low density lipoprotein
LPL gene
Male
Polymorphism, Genetic
Risk Factors
Short Communication
Sudan
Sudan - epidemiology
Sudan
Lipid profile
LPL gene
Coronary heart disease
Risk factors
Sudan
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Cardiovascular disease is stabilizing in high-income countries and has continued to rise in low-to-middle-income countries. Association of lipid profile with lipoprotein lipase gene was studied in case and control subject. The family history, hypertension, diabetes mellitus, smoking and alcohol consumption were the most risk factors for early-onset of coronary heart disease (CHD). Sudanese patients had significantly ( P < 0.05) lower TC and LDL-C levels compared to controls. Allele frequency of LPL D9N, N291S and S447X carrier genotype was 4.2%, 30.7% and 7.1%, respectively. We conclude that lipoprotein lipase polymorphism was not associated with the incidence of CHD in Sudan.
ISSN:2210-6006
2210-6014
2210-6006
DOI:10.1016/j.jegh.2015.04.007