Search Results - "Tyler, Nancy K"

Alveoli increase in number but not size from birth to adulthood in rhesus monkeys by Hyde, Dallas M, Blozis, Shelley A, Avdalovic, Mark V, Putney, Lei F, Dettorre, Rachel, Quesenberry, Nathanial J, Singh, Paramjit, Tyler, Nancy K

“…Postnatal developmental stages of lung parenchyma in rhesus monkeys is about one-third that of humans. Alveoli in humans are reported to be formed up to 8 yr…”
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Morphometry of the Respiratory Tract: Avoiding the Sampling, Size, Orientation, and Reference Traps by Hyde, Dallas M., Tyler, Nancy K., Plopper, Charles G.

“…The extrapolation to humans of studies of infectious or toxic agents injurious to the respiratory system using animal models assumes comparability in the…”
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Accelerated structural decrements in the aging female rhesus macaque lung compared with males by Herring, Matt J, Avdalovic, Mark V, Quesenberry, Cheryl L, Putney, Lei F, Tyler, Nancy K, Ventimiglia, Frank F, St George, Judith A, Hyde, Dallas M

“…Aging is associated with morphometric changes in the lung that lead to decreased lung function. The nonhuman primate lung has been shown to have similar…”
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Ozone Exposure During thE Early Postnatal Period Alters the Timing and Pattern of Alveolar Growth and Development in Nonhuman Primates by Avdalovic, Mark V., Tyler, Nancy K., Putney, Lei, Nishio, Susie J., Quesenberry, Sherri, Singh, Parmjit J, Miller, Lisa A., Schelegle, Edward S., Plopper, Charles G., Vu, Thiennu, Hyde, Dallas M.

“…Exposure to oxidant air pollutants in early childhood, with ozone as the key oxidant, has been linked to significant decrements in pulmonary function in young…”
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Vascular Remodeling Is Airway Generation-Specific in a Primate Model of Chronic Asthma by Avdalovic, Mark V, Putney, Lei F, Schelegle, Edward S, Miller, Lisa, Usachenko, Jodie L, Tyler, Nancy K, Plopper, Charles G, Gershwin, Laurel J, Hyde, Dallas M

“…Changes in the density of bronchial vessels have been proposed as a part of airway remodeling that occurs in chronic asthma. Using an established nonhuman…”
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Activation of Neurokinin-1 Receptors during Ozone Inhalation Contributes to Epithelial Injury and Repair by Oslund, Karen L, Hyde, Dallas M, Putney, Leialoha F, Alfaro, Mario F, Walby, William F, Tyler, Nancy K, Schelegle, Edward S

“…We investigated the importance of neurokinin (NK)-1 receptors in epithelial injury and repair and neutrophil function. Conscious Wistar rats were exposed to 1…”
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Ozone and allergen exposure during postnatal development alters the frequency and airway distribution of CD25+ cells in infant rhesus monkeys by Miller, Lisa A., Gerriets, Joan E., Tyler, Nancy K., Abel, Kristina, Schelegle, Edward S., Plopper, Charles G., Hyde, Dallas M.

“…The epidemiologic link between air pollutant exposure and asthma has been supported by experimental findings, but the mechanisms are not understood. In this…”
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Activation of Calcitonin Gene-Related Peptide Receptor during Ozone Inhalation Contributes to Airway Epithelial Injury and Repair by Oslund, Karen L., Hyde, Dallas M., Putney, Leialoha F., Alfaro, Mario F., Walby, William F., Tyler, Nancy K., Schelegle, Edward S.

“…The authors investigated the importance of the neuropeptide, calcitonin gene-related peptide (CGRP), in epithelial injury, repair, and neutrophil emigration…”
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Design-Based Sampling and Quantitation of the Respiratory Airways by Hyde, Dallas M., Harkema, Jack R., Tyler, Nancy K., Plopper, Charles G.

“…Design-based quantitation of the nasal cavity, larynx and tracheobronchial conducting airways after exposure to inhaled toxicants requires complete measurement…”
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Chronic Aeroallergen during Infancy Enhances Eotaxin-3 Expression in Airway Epithelium and Nerves by Chou, Debbie L, Daugherty, Bruce L, McKenna, Erin K, Hsu, Willy M, Tyler, Nancy K, Plopper, Charles G, Hyde, Dallas M, Schelegle, Edward S, Gershwin, Laurel J, Miller, Lisa A

“…We have documented that exposure of rhesus monkeys to house dust mite aeroallergen during postnatal development resulted in significant recruitment of…”
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Oxidant-Injured Airway Epithelial Cells Upregulate Thioredoxin but Do Not Produce Interleukin-8 by Oslund, Karen L, Miller, Lisa A, Usachenko, Jodie L, Tyler, Nancy K, Wu, Reen, Hyde, Dallas M

“…We tested the hypothesis that oxidant-injured cells upregulate thioredoxin, whereas oxidant-stressed, but not injured, cells upregulate interleukin (IL)-8…”
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Heterogeneity of Clara Cell Glutathione . A Possible Basis for Differences in Cellular Responses to Pulmonary Cytotoxicants by West, Jay A. A, Chichester, Christine H, Buckpitt, Alan R, Tyler, Nancy K, Brennan, Patricia, Helton, Cimity, Plopper, Charles G

“…Clara-cell populations show a high degree of variation in susceptibility to injury by bioactivated cytotoxicants. Because glutathione (GSH) is critical for…”
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Cancer-associated retinopathy (CAR syndrome) with antibodies reacting with retinal, optic-nerve, and cancer cells by Thirkill, C E, FitzGerald, P, Sergott, R C, Roth, A M, Tyler, N K, Keltner, J L

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The effect of house dust mite aeroallergen and air pollutant exposures during infancy by Miller, Lisa A, Hyde, Dallas M, Gershwin, Laurel J, Schelegle, Edward S, Fanucchi, Michelle V, Evans, Michael J, Gerriets, Joan E, Putney, Lei F, Stovall, Mary Y, Tyler, Nancy K, Usachenko, Jodie L, Plopper, Charles G

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Effect of murine gamma interferon on the cellular responses to bleomycin in mice by Hyde, D M, Henderson, T S, Giri, S N, Tyler, N K, Stovall, M Y

“…Because in vitro studies have shown inhibition of fibroblast proliferation and collagen synthesis by interferon, we tested the hypothesis that murine gamma…”
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Antibody indications of secondary and superimposed retinal hypersensitivity in retinitis pigmentosa by Thirkill, C E, Roth, A M, Takemoto, D J, Tyler, N K, Keltner, J L

“…Antibody reactions with recognized retinopathy-inducing retinal antigens may be interpreted to reflect ongoing autoimmune events responsible for some forms of…”
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Mean alveolar face length, a design‐based measurement for emphysema by Hyde, Dallas M, Tyler, Nancy K, Putney, Lei F, Janssen, William J, Henson, Peter M, DeHoff, Robert T

“…Emphysema, a chronic obstructive lung disease, is characterized by loss of elasticity of the lung tissue and destruction of interalveolar septa that results in…”
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Quantitating live cells and explant tissues in culture: from static to chemotaxis by Hyde, Dallas M, Avdalovic, Mark, Usachencho, Jodie L, Tyler, Nancy K

“…Mechanistic investigations often require the use of cells or tissue explants in culture. Depending on the thickness of the culture, from single cells to…”
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Antibody reactions with retina and cancer-associated antigens in 10 patients with cancer-associated retinopathy by Thirkill, C E, Keltner, J L, Tyler, N K, Roth, A M

“…Our objectives were to determine what clinical characteristics are common to the form of cancer-associated retinopathy (CAR) encountered in patients with…”
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Management and monitoring of cancer-associated retinopathy by Keltner, J L, Thirkill, C E, Tyler, N K, Roth, A M

“…Cancer-associated retinopathy is a rare paraneoplastic event that can involve allergic reactions and result in retinal degradation. A patient, who had a…”
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