Search Results - "Tyler, N."

Epistasis in protein evolution by Starr, Tyler N., Thornton, Joseph W.

“…The structure, function, and evolution of proteins depend on physical and genetic interactions among amino acids. Recent studies have used new strategies to…”
Get full text

Onset of meso-scale turbulence in active nematics by Doostmohammadi, Amin, Shendruk, Tyler N., Thijssen, Kristian, Yeomans, Julia M.

“…Meso-scale turbulence is an innate phenomenon, distinct from inertial turbulence, that spontaneously occurs at low Reynolds number in fluidized biological…”
Get full text

Incidence and Costs of Neonatal Abstinence Syndrome Among Infants With Medicaid: 2004 - 2014 by Winkelman, Tyler N A, Villapiano, Nicole, Kozhimannil, Katy B, Davis, Matthew M, Patrick, Stephen W

“…To describe incidence, health care use, and cost trends for infants with neonatal abstinence syndrome (NAS) who are covered by Medicaid compared with other…”
Get full text

Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016 by Starr, Tyler N., Greaney, Allison J., Dingens, Adam S., Bloom, Jesse D.

“…Monoclonal antibodies and antibody cocktails are a promising therapeutic and prophylaxis for coronavirus disease 2019 (COVID-19). However, ongoing evolution of…”
Get full text

Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding by Starr, Tyler N., Greaney, Allison J., Hilton, Sarah K., Ellis, Daniel, Crawford, Katharine H.D., Dingens, Adam S., Navarro, Mary Jane, Bowen, John E., Tortorici, M. Alejandra, Walls, Alexandra C., King, Neil P., Veesler, David, Bloom, Jesse D.

“…The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor and is a major determinant of host range and…”
Get full text

Passive Janus particles are self-propelled in active nematics by Loewe, Benjamin, Shendruk, Tyler N

“…Abstract While active systems possess notable potential to form the foundation of new classes of autonomous materials (Zhang et al 2021 Nat. Rev. Mater. 6…”
Get full text

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection by Greaney, Allison J, Loes, Andrea N, Gentles, Lauren E, Crawford, Katharine H D, Starr, Tyler N, Malone, Keara D, Chu, Helen Y, Bloom, Jesse D

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with mutations in key antibody epitopes has raised concerns that…”
Get more information

Implicit attitudes toward obesity-related cues and their relation to body mass index, psychosocial functioning, and health behavior by Cummings, Caroline, Livingston, Tyler N

“…Differences in automatic cognitive processes exist among individuals with overweight and obesity, thus there is a need to expand our conceptualization of…”
Get full text

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains by Starr, Tyler N, Greaney, Allison J, Stewart, Cameron M, Walls, Alexandra C, Hannon, William W, Veesler, David, Bloom, Jesse D

“…SARS-CoV-2 continues to acquire mutations in the spike receptor-binding domain (RBD) that impact ACE2 receptor binding, folding stability, and antibody…”
Get full text

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies by Greaney, Allison J., Starr, Tyler N., Barnes, Christopher O., Weisblum, Yiska, Schmidt, Fabian, Caskey, Marina, Gaebler, Christian, Cho, Alice, Agudelo, Marianna, Finkin, Shlomo, Wang, Zijun, Poston, Daniel, Muecksch, Frauke, Hatziioannou, Theodora, Bieniasz, Paul D., Robbiani, Davide F., Nussenzweig, Michel C., Bjorkman, Pamela J., Bloom, Jesse D.

“…Monoclonal antibodies targeting a variety of epitopes have been isolated from individuals previously infected with SARS-CoV-2, but the relative contributions…”
Get full text

Weak coupling between energetic status and the timing of reproduction in an Arctic ungulate by Tyler, N. J. C., Post, E., Hazlerigg, D. G.

“…Bioenergetic constraints are the ultimate determinant of the timing of reproduction, and seasonal breeding is consequently a widely observed trait. Consistent…”
Get full text

Opening the silvicultural toolbox: A new framework for conserving biodiversity in Chilean timber plantations by McFadden, Tyler N., Dirzo, Rodolfo

“…•The role of timber plantations in global conservation efforts is hotly debated.•We examined biodiversity maintenance and loss in Chilean plantations.•Biases…”
Get full text

Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies by Greaney, Allison J., Loes, Andrea N., Crawford, Katharine H.D., Starr, Tyler N., Malone, Keara D., Chu, Helen Y., Bloom, Jesse D.

“…The evolution of SARS-CoV-2 could impair recognition of the virus by human antibody-mediated immunity. To facilitate prospective surveillance for such…”
Get full text

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19 by Starr, Tyler N, Greaney, Allison J, Addetia, Amin, Hannon, William W, Choudhary, Manish C, Dingens, Adam S, Li, Jonathan Z, Bloom, Jesse D

“…Antibodies are a potential therapy for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but the risk of the virus evolving to escape them remains…”
Get full text

Damage detection in non-planar carbon fiber-reinforced polymer laminates via electrical impedance tomography with surface-mounted electrodes and directional sensitivity matrices by Sannamani, Monica, Gao, Jinling, Chen, Weinong W., Tallman, Tyler N.

“…Carbon fiber reinforced polymers (CFRPs) have emerged as promising alternatives to traditional metals and alloys in weight-conscious applications such as…”
Get full text

Deep mutational scans of XBB.1.5 and BQ.1.1 reveal ongoing epistatic drift during SARS-CoV-2 evolution by Taylor, Ashley L, Starr, Tyler N

“…Substitutions that fix between SARS-CoV-2 variants can transform the mutational landscape of future evolution via epistasis. For example, large epistatic…”
Get full text

Trophic state assessment of global inland waters using a MODIS-derived Forel-Ule index by Wang, Shenglei, Li, Junsheng, Zhang, Bing, Spyrakos, Evangelos, Tyler, Andrew N., Shen, Qian, Zhang, Fangfang, Kuster, Tiit, Lehmann, Moritz K., Wu, Yanhong, Peng, Dailiang

“…Eutrophication of inland waters is considered a serious global environmental problem. Satellite remote sensing (RS) has been established as an important source…”
Get full text

ACE2 binding is an ancestral and evolvable trait of sarbecoviruses by Starr, Tyler N., Zepeda, Samantha K., Walls, Alexandra C., Greaney, Allison J., Alkhovsky, Sergey, Veesler, David, Bloom, Jesse D.

“…Two different sarbecoviruses have caused major human outbreaks in the past two decades 1 , 2 . Both of these sarbecoviruses, SARS-CoV-1 and SARS-CoV-2, engage…”
Get full text

Amphetamine- and Opioid-Affected Births: Incidence, Outcomes, and Costs, United States, 2004-2015 by Admon, Lindsay K, Bart, Gavin, Kozhimannil, Katy B, Richardson, Caroline R, Dalton, Vanessa K, Winkelman, Tyler N A

“…To estimate trends in incidence, outcomes, and costs among hospital deliveries related to amphetamines and opioids. We analyzed 2004-to-2015 data from the…”
Get full text

Perinatal mood and anxiety disorders, serious mental illness, and delivery-related health outcomes, United States, 2006-2015 by McKee, Kimberly, Admon, Lindsay K, Winkelman, Tyler N A, Muzik, Maria, Hall, Stephanie, Dalton, Vanessa K, Zivin, Kara

“…National estimates of perinatal mood and anxiety disorders (PMAD) and serious mental illness (SMI) among delivering women over time, as well as associated…”
Get full text