Search Results - "Tyagi, Sandeep"

Renormalized charge and dielectric effects in colloidal interactions: a numerical solution of the nonlinear Poisson–Boltzmann equation for unknown boundary conditions by Schlaich, Alexander, Tyagi, Sandeep, Kesselheim, Stefan, Sega, Marcello, Holm, Christian

“… The Derjaguin–Landau–Verwey–Overbeek (DLVO) theory, introduced more than 70 years ago, is a hallmark of colloidal particle modeling. For highly charged…”
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The peroxisome proliferator-activated receptor: A family of nuclear receptors role in various diseases by Tyagi, Sandeep, Gupta, Paras, Saini, Arminder Singh, Kaushal, Chaitnya, Sharma, Saurabh

“…Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of nuclear hormone receptor superfamily comprising of the…”
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Targeting DnaN for tuberculosis therapy using novel griselimycins by Kling, Angela, Lukat, Peer, Almeida, Deepak V., Bauer, Armin, Fontaine, Evelyne, Sordello, Sylvie, Zaburannyi, Nestor, Herrmann, Jennifer, Wenzel, Silke C., König, Claudia, Ammerman, Nicole C., Barrio, María Belén, Borchers, Kai, Bordon-Pallier, Florence, Brönstrup, Mark, Courtemanche, Gilles, Gerlitz, Martin, Geslin, Michel, Hammann, Peter, Heinz, Dirk W., Hoffmann, Holger, Klieber, Sylvie, Kohlmann, Markus, Kurz, Michael, Lair, Christine, Matter, Hans, Nuermberger, Eric, Tyagi, Sandeep, Fraisse, Laurent, Grosset, Jacques H., Lagrange, Sophie, Müller, Rolf

“…The discovery of Streptomyces-produced streptomycin founded the age of tuberculosis therapy. Despite the subsequent development of a curative regimen for this…”
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Clofazimine shortens the duration of the first-line treatment regimen for experimental chemotherapy of tuberculosis by Tyagi, Sandeep, Ammerman, Nicole C., Li, Si-Yang, Adamson, John, Converse, Paul J., Swanson, Rosemary V., Almeida, Deepak V., Grosset, Jacques H.

“…A key drug for the treatment of leprosy, clofazimine has recently been associated with highly effective and significantly shortened regimens for the treatment…”
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Powerful Bactericidal and Sterilizing Activity of a Regimen Containing PA-824, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis by NUERMBERGER, Eric, TYAGI, Sandeep, TASNEEN, Rokeya, WILLIAMS, Kathy N, ALMEIDA, Deepak, ROSENTHAL, Ian, GROSSET, Jacques H

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Dose optimization of TBI-223 for enhanced therapeutic benefit compared to linezolid in antituberculosis regimen by Strydom, Natasha, Ernest, Jacqueline P., Imperial, Marjorie, Solans, Belén P., Wang, Qianwen, Tasneen, Rokeya, Tyagi, Sandeep, Soni, Heena, Garcia, Andrew, Bigelow, Kristina, Gengenbacher, Martin, Zimmerman, Matthew, Xie, Min, Sarathy, Jansy P., Yang, Tian J., Dartois, Véronique, Nuermberger, Eric L., Savic, Radojka M.

“…TBI-223, a novel oxazolidinone for tuberculosis, is designed to provide improved efficacy and safety compared to linezolid in combination with bedaquiline and…”
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Enhanced Bactericidal Activity of Rifampin and/or Pyrazinamide When Combined with PA-824 in a Murine Model of Tuberculosis by TASNEEN, Rokeya, TYAGI, Sandeep, WILLIAMS, Kathy, GROSSET, Jacques, NUERMBERGER, Eric

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An iterative, fast, linear-scaling method for computing induced charges on arbitrary dielectric boundaries by Tyagi, Sandeep, Süzen, Mehmet, Sega, Marcello, Barbosa, Marcia, Kantorovich, Sofia S, Holm, Christian

“…Simulating coarse-grained models of charged soft-condensed matter systems in presence of dielectric discontinuities between different media requires an…”
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Characterization of mouse models of Mycobacterium avium complex infection and evaluation of drug combinations by Andréjak, Claire, Almeida, Deepak V, Tyagi, Sandeep, Converse, Paul J, Ammerman, Nicole C, Grosset, Jacques H

“…The Mycobacterium avium complex is the most common cause of nontuberculous mycobacterial lung disease worldwide; yet, an optimal treatment regimen for M. avium…”
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Paradoxical Effect of Isoniazid on the Activity of Rifampin-Pyrazinamide Combination in a Mouse Model of Tuberculosis by ALMEIDA, Deepak, NUERMBERGER, Eric, TASNEEN, Rokeya, ROSENTHAL, Ian, TYAGI, Sandeep, WILLIAMS, Kathy, PELOQUIN, Charles, GROSSET, Jacques

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Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model by Rosenthal, Ian M, Zhang, Ming, Williams, Kathy N, Peloquin, Charles A, Tyagi, Sandeep, Vernon, Andrew A, Bishai, William R, Chaisson, Richard E, Grosset, Jacques H, Nuermberger, Eric L

“…Availability of an ultra-short-course drug regimen capable of curing patients with tuberculosis in 2 to 3 mo would significantly improve global control…”
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PA-824 Exhibits Time-Dependent Activity in a Murine Model of Tuberculosis by AHMAD, Zahoor, PELOQUIN, Charles A, SINGH, Rajendra P, DERENDORF, Hartmut, TYAGI, Sandeep, GINSBERG, Ann, GROSSET, Jacques H, NUERMBERGER, Eric L

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A multi-antigenic MVA vaccine increases efficacy of combination chemotherapy against Mycobacterium tuberculosis by Leung-Theung-Long, Stéphane, Coupet, Charles-Antoine, Gouanvic, Marie, Schmitt, Doris, Ray, Aurélie, Hoffmann, Chantal, Schultz, Huguette, Tyagi, Sandeep, Soni, Heena, Converse, Paul J, Arias, Lilibeth, Kleinpeter, Patricia, Sansas, Benoît, Mdluli, Khisimuzi, Vilaplana, Cristina, Cardona, Pere-Joan, Nuermberger, Eric, Marchand, Jean-Baptiste, Silvestre, Nathalie, Inchauspé, Geneviève

“…Despite the existence of the prophylactic Bacille Calmette-Guérin (BCG) vaccine, infection by Mycobacterium tuberculosis (Mtb) remains a major public health…”
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Bactericidal Activity of the Nitroimidazopyran PA-824 in a Murine Model of Tuberculosis by TYAGI, Sandeep, NUERMBERGER, E, YOSHIMATSU, T, WILLIAMS, K, ROSENTHAL, I, LOUNIS, N, BISHAI, W, GROSSET, J

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Designer Arrays for Defined Mutant Analysis To Detect Genes Essential for Survival of Mycobacterium tuberculosis in Mouse Lungs by Lamichhane, Gyanu, Tyagi, Sandeep, Bishai, William R

“…The mechanisms by which Mycobacterium tuberculosis elicits disease are complex, involving a large repertoire of bacterial genes that are required for in vivo…”
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Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer by Converse, Paul J, Almeida, Deepak V, Tasneen, Rokeya, Saini, Vikram, Tyagi, Sandeep, Ammerman, Nicole C, Li, Si-Yang, Anders, Nicole M, Rudek, Michelle A, Grosset, Jacques H, Nuermberger, Eric L

“…ClinicalTrials.gov NCT03474198, NCT01659437…”
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Moxifloxacin-containing Regimen Greatly Reduces Time to Culture Conversion in Murine Tuberculosis by Nuermberger, Eric L, Yoshimatsu, Tetsuyuki, Tyagi, Sandeep, O'Brien, Richard J, Vernon, Andrew N, Chaisson, Richard E, Bishai, William R, Grosset, Jacques H

“…Tuberculosis continues to be a major cause of morbidity and mortality in the world. The expansion of tuberculosis control programs has been limited by the…”
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Combination Chemotherapy with the Nitroimidazopyran PA-824 and First-Line Drugs in a Murine Model of Tuberculosis by NUERMBERGER, Eric, ROSENTHAL, Ian, TYAGI, Sandeep, WILLIAMS, Kathy N, ALMEIDA, Deepak, PELOQUIN, Charles A, BISHAI, William R, GROSSET, Jacques H

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Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease by Converse, Paul J, Tyagi, Sandeep, Xing, Yalan, Li, Si-Yang, Kishi, Yoshito, Adamson, John, Nuermberger, Eric L, Grosset, Jacques H

“…Treatment of Buruli ulcer, or Mycobacterium ulcerans disease, has shifted from surgical excision and skin grafting to antibiotic therapy usually with 8 weeks…”
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Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide by Grosset, Jacques, Almeida, Deepak, Converse, Paul J, Tyagi, Sandeep, Li, Si-Yang, Ammerman, Nicole C, Pym, Alexander S, Wallengren, Kristina, Hafner, Richard, Lalloo, Umesh, Swindells, Susan, Bishai, William R

“…Standard tuberculosis (TB) treatment includes an initial regimen containing drugs that are both rapidly bactericidal (isoniazid) and sterilizing (rifampin and…”
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