Search Results - "Tyagi, Alpana"
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Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis
Published in Oncogene (06-03-2003)“…A loss of functional androgen receptor and an enhanced expression of growth factor receptors and associated ligands are causal genetic events in prostate…”
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Journal Article -
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Silibinin Efficacy against Human Hepatocellular Carcinoma
Published in Clinical cancer research (01-12-2005)“…Purpose: Hepatocellular carcinoma (HCC) is one of the most common recurrent malignancies, for which, currently, there is no effective therapy. Considering the…”
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The Cancer Preventive Flavonoid Silibinin Causes Hypophosphorylation of Rb/p107 and Rb2/p130 Via Modulation of Cell Cycle Regulators in Human Prostate Carcinoma DU145 Cells
Published in Cell cycle (Georgetown, Tex.) (01-03-2002)“…Phosphorylation status of retinoblastoma (Rb) and related proteins is important to drive cell cycle progression. In hyperphosphorylated state, they are growth…”
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Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells
Published in The Prostate (01-11-2002)“…BACKGROUND The tremendous impact of prostate cancer (PCA) on the US male population has led to an increased attention on its prevention and on therapeutic…”
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Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI–CDK–cyclin cascade, and caspase 3 and PARP cleavages
Published in Carcinogenesis (New York) (01-09-2004)“…Bladder cancer is the fourth and eighth most common cancer in men and women in the USA, respectively. Flavonoid phytochemicals are being studied for both…”
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Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate carcinoma LNCaP cells: role in prostate cancer prevention
Published in Molecular cancer therapeutics (01-05-2002)“…Several studies have identified silibinin as an anticarcinogenic agent. Recently, we showed that silibinin inhibits cell growth via G1 arrest, leading to…”
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Changes in structure and functions of prostate by long‐term administration of an androgen, testosterone enanthate, in rhesus monkey (Macaca mulatta)
Published in The Anatomical record (01-12-1998)“…The increasing use of androgens in clinical trials for developing a safe, effective, and reversible male contraceptive has necessitated a critical evaluation…”
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An In-Depth Study of Peer Influence on Collective Decision Making for Multi-party Access Control (Invited Paper)
Published in 2016 IEEE 17th International Conference on Information Reuse and Integration (IRI) (01-07-2016)“…In this paper, we discuss the results of a 159-participant human-subject study on peer influence in multiparty access control decisions in social network…”
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Conference Proceeding -
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Studies on some structural and functional aspects of human spermatozoa in relation to fertility
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Dissertation -
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Effects of long term administration of testosterone enanthate on glucose metabolism in rhesus monkeys
Published in Contraception (Stoneham) (01-05-1999)“…The effects of long term administration of testosterone enanthate (TE) on glucose metabolism including glucose tolerance test (GTT) and fasting serum insulin…”
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Effects of long-term use of testosterone enanthate. II. Effects on lipids, high and low density lipoprotein cholesterol and liver function parameters
Published in International journal of andrology (01-12-1999)“…The present study was designed to evaluate the effects of long‐term administration of testosterone enanthate (TE) on lipid and liver function parameters in…”
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Effects of long-term treatment with testosterone enanthate in rhesus monkeys: I. Pharmacokinetics of testosterone, testicular volume and liver metabolism of testosterone
Published in International journal of andrology (01-06-1999)“…The effects of long‐term administration of testosterone enanthate on the pharmacokinetics and bioavailability of testosterone were studied in adult male rhesus…”
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Journal Article