Search Results - "Twilley, Danielle"

The Role of the PTEN Tumor Suppressor Gene and Its Anti-Angiogenic Activity in Melanoma and Other Cancers by Maphutha, Jacqueline, Twilley, Danielle, Lall, Namrita

“…Human malignant melanoma and other solid cancers are largely driven by the inactivation of tumor suppressor genes and angiogenesis. Conventional treatments for…”
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Anti-SARS-CoV Natural Products With the Potential to Inhibit SARS-CoV-2 (COVID-19) by Verma, Surjeet, Twilley, Danielle, Esmear, Tenille, Oosthuizen, Carel B., Reid, Anna-Mari, Nel, Marizé, Lall, Namrita

“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the disease COVID-19, was declared a pandemic in early 2020. The objective of…”
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Pathogenesis of Keratinocyte Carcinomas and the Therapeutic Potential of Medicinal Plants and Phytochemicals by Josiah, Andrea Jess, Twilley, Danielle, Pillai, Sreejarani Kesavan, Ray, Suprakas Sinha, Lall, Namrita

“…Keratinocyte carcinoma (KC) is a form of skin cancer that develops in keratinocytes, which are the predominant cells present in the epidermis layer of the…”
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Mupirocin Promotes Wound Healing by Stimulating Growth Factor Production and Proliferation of Human Keratinocytes by Twilley, Danielle, Reva, Oleg, Meyer, Debra, Lall, Namrita

“…Mupirocin has been reported for its role in the treatment of infected wounds through its antibacterial activity, however the role of mupirocin in promoting…”
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Molecules from nature: Reconciling biodiversity conservation and global healthcare imperatives for sustainable use of medicinal plants and fungi by Howes, Melanie‐Jayne R., Quave, Cassandra L., Collemare, Jérôme, Tatsis, Evangelos C., Twilley, Danielle, Lulekal, Ermias, Farlow, Andrew, Li, Liping, Cazar, María‐Elena, Leaman, Danna J., Prescott, Thomas A. K., Milliken, William, Martin, Cathie, De Canha, Marco Nuno, Lall, Namrita, Qin, Haining, Walker, Barnaby E., Vásquez‐Londoño, Carlos, Allkin, Bob, Rivers, Malin, Simmonds, Monique S. J., Bell, Elizabeth, Battison, Alex, Felix, Juri, Forest, Felix, Leon, Christine, Williams, China, Nic Lughadha, Eimear

“…Plants and fungi have provided, or inspired, key pharmaceuticals for global health challenges, including cancer, heart disease, dementia, and malaria, and are…”
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Evaluation of Wound Healing and Antibacterial Potential of Greyia radlkoferi Szyszyl. Ethanolic Leaf Extract by Loggenberg, Samantha Rae, Twilley, Danielle, De Canha, Marco Nuno, Meyer, Debra, Mabena, Ephraim Cebisa, Lall, Namrita

“…Angiogenesis is an essential mechanism in both physiological and pathological functions, such as wound healing and cancer metastasis. Several growth factors…”
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Antiproliferative Activity of Buddleja saligna (Willd.) against Melanoma and In Vivo Modulation of Angiogenesis by Twilley, Danielle, Thipe, Velaphi C, Kishore, Navneet, Bloebaum, Pierce, Roma-Rodrigues, Catarina, Baptista, Pedro V, Fernandes, Alexandra R, Selepe, Mamoalosi A, Langhansova, Lenka, Katti, Kattesh, Lall, Namrita

“…Melanoma cells secrete pro-angiogenic factors, which stimulates growth, proliferation and metastasis, and therefore are key therapeutic targets. (BS), and an…”
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Cannabidiol-Mediated Green Synthesis, Characterization, and Cytotoxicity of Metal Nanoparticles in Human Keratinocyte Cells by Josiah, Andrea Jess, Pillai, Sreejarani K, Cordier, Werner, Nell, Margo, Twilley, Danielle, Lall, Namrita, Ray, Suprakas Sinha

“…This study investigated a unique one-pot microwave-assisted green synthesis method of gold (Au) and silver (Ag) nanoparticles (NPs) using cannabidiol (CBD) as…”
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Sideritis Perfoliata (Subsp. Perfoliata ) Nutritive Value and Its Potential Medicinal Properties by Lall, Namrita, Chrysargyris, Antonios, Lambrechts, Isa, Fibrich, Bianca, Blom Van Staden, Analike, Twilley, Danielle, de Canha, Marco Nuno, Oosthuizen, Carel Basson, Bodiba, Dikonketso, Tzortzakis, Nikolaos

“…L. subsp. is an endemic species of the Eastern Mediterranean region with several uses in traditional medicine. The present study aims to explore the unknown…”
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Assessing Anti-Inflammatory Activities and Compounds in Switchgrass (Panicum virgatum) by Ho, Khanh-Van, Efrat, Novianus, Schreiber, Kathy L., Vo, Phuc H., De Canha, Marco N., van Staden, Analike Blom, Payne, Bianca D., Oosthuizen, Carel B., Twilley, Danielle, Lei, Zhentian, Sumner, Lloyd W., Brown, Charles R., Lall, Namrita, Lin, Chung-Ho

“…Switchgrass is a bioenergy feedstock that potentially possesses multiple health benefits. However, the biological properties and associated bioactive compounds…”
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A review on traditionally used South African medicinal plants, their secondary metabolites and their potential development into anticancer agents by Twilley, Danielle, Rademan, Sunelle, Lall, Namrita

“…Approximately 70% of anticancer drugs were developed or derived from natural products or plants. Southern Africa boasts an enormous floral diversity with…”
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Evaluating the effects of various ethanolic medicinal plant extracts on metastatic breast cancer proliferation, invasion, and expression of a novel potential drug target; CD82 metastatic suppressor protein, and on in vivo angiogenesis using the ex ovo yolk sac membrane (YSM) assay by Loggenberg, Samantha, Twilley, Danielle, Lall, Namrita

“…Purpose Breast cancer metastasis relies on cellular invasion and angiogenesis facilitated by the downregulation of metastatic suppressor proteins like Cluster…”
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The stimulating effect of extracts of South African plants on melanin production and their antibacterial activity against Cutibacterium acnes by Lall, Namrita, Steyn, Aimee, Blom van Staden, Analike, Kentane, Thobeka, Twilley, Danielle

“…•Sideroxylon inerme ethanolic extract showed an MIC of 125 µg/mL against Cutibacterium acnes.•Bulbine frutescens ethanolic extract increased tyrosinase…”
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Isolation of Flavonoids and Flavonoid Glycosides from Myrsine africana and Their Inhibitory Activities against Mushroom Tyrosinase by Kishore, Navneet, Twilley, Danielle, Blom van Staden, Analike, Verma, Praveen, Singh, Bikram, Cardinali, Giorgia, Kovacs, Daniela, Picardo, Mauro, Kumar, Vivek, Lall, Namrita

“…Bioassay-guided fractionation of the methanol extract of the shoots of Myrsine africana led to the isolation of the new compound myricetin…”
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Antimicrobial and cytotoxic effects of medicinal plants traditionally used for the treatment of sexually transmitted diseases by Dembetembe, Tanyaradzwa Tiandra, Rademan, Sunelle, Twilley, Danielle, Banda, Gill Whittington, Masinga, Lulama, Lall, Namrita, Kritzinger, Quenton

“…Sexually transmitted diseases (STDs) are a major problem internationally, with approximately one million new infections recorded daily. Antibiotic resistance…”
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One‐Step Synthesis of Metal Oxide Nanoparticles Using Cannabidiol: Characterisation and Cytotoxicity Assessment in Human Keratinocyte Cells by Josiah, Andrea Jess, Pillai, Sreejarani Kesavan, Cordier, Werner, Nell, Margo, Lall, Namrita, Twilley, Danielle, Ray, Suprakas Sinha

“…This research paper explores the field of nanobiotechnology, focusing on the design, characterisation, and potential dermal applications of metal oxide…”
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Antiproliferative Activity of IBuddleja saligna/I against Melanoma and IIn Vivo/I Modulation of Angiogenesis by Twilley, Danielle, Thipe, Velaphi C, Kishore, Navneet, Bloebaum, Pierce, Roma-Rodrigues, Catarina, Baptista, Pedro V, Fernandes, Alexandra R, Selepe, Mamoalosi A, Langhansova, Lenka, Katti, Kattesh, Lall, Namrita

“…Melanoma cells secrete pro-angiogenic factors, which stimulates growth, proliferation and metastasis, and therefore are key therapeutic targets. Buddleja…”
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Anti-inflammatory and antiproliferative activity of Helichrysum odoratissimum Sweet. against lung cancer by Esmear, Tenille, Twilley, Danielle, Thipe, Velaphi Clement, Katti, Kattesh V., Mandiwana, Vusani, Kalombo, Michel Lonji, Ray, Suprakas Sinha, Rikhotso-Mbungela, Rirhandzu, Bovilla, Venugopal Reddy, Madhunapantula, SubbaRao, Langhanshova, Lenka, Roma-Rodrigues, Catarina, Fernandes, Alexandra R., Baptista, Pedro, Hlati, Silvestre, Pretorius, Judey, Lall, Namrita

“…•First report of helichrysum odoratissimum ethanolic extract (HO) against A549 lung cancer with an IC50 of 83.43 ± 1.60 µg/mL.•HO inhibited COX-2 and 5-LOX…”
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Pluripharmacological potential of Mascarene endemic plant leaf extracts by Rummun, Nawraj, Payne, Bianca, Blom van Staden, Analike, Twilley, Danielle, Houghton, Brittany, Horrocks, Paul, Li, Wen-Wu, Lall, Namrita, Bahorun, Theeshan, Neergheen, Vidushi S.

“…Tropical forests of the islands of the West Indian Ocean region, have a rich and diverse collection of unique plants containing a multitude of chemical…”
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Cytotoxicity of syringin and 4-methoxycinnamyl alcohol isolated from Foeniculum vulgare on selected human cell lines by Lall, Namrita, Kishore, Navneet, Binneman, Brigitte, Twilley, Danielle, van de Venter, Maryna, Plessis-Stoman, Debbie du, Boukes, Gerhardt, Hussein, Ahmed

“…This study was carried out to determine the cytotoxic effect of seven plant extracts and the isolated compounds - syringin and 4-methoxycinnamyl alcohol - on…”
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