Search Results - "Twigg, S M"

Diabetes and Nonalcoholic Fatty Liver Disease: A Pathogenic Duo by Williams, K. H, Shackel, N. A, Gorrell, M. D, McLennan, S. V, Twigg, S. M

“…Recent data increasingly support a complex interplay between the metabolic condition diabetes mellitus and the pathologically defined nonalcoholic fatty liver…”
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Thyroid autoimmunity in Type 1 diabetes: systematic review and meta-analysis by Shun, C. B., Donaghue, K. C., Phelan, H., Twigg, S. M., Craig, M. E.

“…Aims To review the incidence and evidence for screening for thyroid autoimmunity and thyroid dysfunction in Type 1 diabetes. Methods Systematic review and…”
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Blood β-hydroxybutyrate vs. urine acetoacetate testing for the prevention and management of ketoacidosis in Type 1 diabetes: a systematic review by Klocker, A. A., Phelan, H., Twigg, S. M., Craig, M. E.

“…Abstact Aim Diabetic ketoacidosis is a life‐threatening complication of Type 1 diabetes. Blood β‐hydroxybutyrate testing is now widely available as an…”
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The emerging role of skeletal muscle extracellular matrix remodelling in obesity and exercise by Martinez‐Huenchullan, S, McLennan, S. V, Verhoeven, A, Twigg, S. M, Tam, C. S

“…Summary Skeletal muscle extracellular matrix remodelling has been proposed as a new feature associated with obesity and metabolic dysfunction. Exercise…”
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Monocyte CD147 is induced by advanced glycation end products and high glucose concentration: possible role in diabetic complications by Bao, W, Min, D, Twigg, S M, Shackel, N A, Warner, F J, Yue, D K, McLennan, S V

“…CD147 is a highly glycosylated transmembrane protein that is known to play a role in regulation of many protein families. It has the unique ability to maintain…”
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Mitochondrial DNA content in peripheral blood monocytes: relationship with age of diabetes onsetand diabetic complications by Wong, J, McLennan, S. V, Molyneaux, L, Min, D, Twigg, S. M, Yue, D. K

“…Aims/hypothesis We examined whether age of type 2 diabetes onset is related to mitochondrial DNA content in peripheral blood monocytes (PBMCs). Methods PBMCs…”
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Topically Applied Connective Tissue Growth Factor/CCN2 Improves Diabetic Preclinical Cutaneous Wound Healing: Potential Role for CTGF in Human Diabetic Foot Ulcer Healing by McLennan, Susan V., Lo, L., Boughton, Philip, Henshaw, F. R., Twigg, Stephen M.

“…Aims/Hypothesis. Topical application of CTGF/CCN2 to rodent diabetic and control wounds was examined. In parallel research, correlation of CTGF wound fluid…”
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Connective Tissue Growth Factor Mediates High Glucose Effects on Matrix Degradation through Tissue Inhibitor of Matrix Metalloproteinase Type 1: Implications for Diabetic Nephropathy by McLennan, S. V, Wang, X. Y, Moreno, V, Yue, D. K, Twigg, S. M

“…High glucose concentration inhibits matrix degradation and affects the activities of the enzymes responsible, the matrix metalloproteinases (MMPs) and their…”
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novel primate model of delayed wound healing in diabetes: dysregulation of connective tissue growth factor by Thomson, S. E, McLennan, S. V, Hennessy, A, Boughton, P, Bonner, J, Zoellner, H, Yue, D. K, Twigg, S. M

“…Aims/hypothesis Chronic non-healing wounds are a common complication of diabetes. Prolonged inflammation and decreased matrix accumulation may contribute…”
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Diastolic dysfunction and abnormalities of the microcirculation in type 2 diabetes by Brooks, B. A., Franjic, B., Ban, C. R., Swaraj, K., Yue, D. K., Celermajer, D. S., Twigg, S. M.

“…Aim:  Diabetic cardiomyopathy is an increasingly recognized entity. The pathogenic factors that may contribute to its development, especially the earliest…”
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Congestive heart failure presence predicts delayed healing of foot ulcers in diabetes: An audit from a multidisciplinary high-risk foot clinic by Rhou, Yoon Ji Jina, Henshaw, F.R, McGill, M.J, Twigg, S.M

“…Abstract Aims This retrospective study aimed to investigate both established and less well-explored factors as potential predictive variables for failed and…”
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The danger of using inappropriate point-of-care glucose meters in patients on icodextrin dialysis by Perera, N. J., Stewart, P. M., Williams, P. F., Chua, E. L., Yue, D. K., Twigg, S. M.

“…Diabet. Med. 28, 1272–1276 (2011) Aims  Icodextrin is a glucose polymer used to maintain an osmotic gradient in peritoneal dialysis. Metabolites of icodextrin…”
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Metabolic syndrome in type 1 diabetes and its association with diabetes complications by Lee, Angela S., Twigg, S. M., Flack, J. R.

“…Aim To assess the prevalence of metabolic syndrome in type 1 diabetes, and its age‐related association with diabetes complications. Methods Australian National…”
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The time has come to target connective tissue growth factor in diabetic complications by TWIGG, S. M, COOPER, M. E

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Young‐onset type 2 diabetes and younger current age: increased susceptibility to retinopathy in contrast to other complications by Middleton, T. L., Constantino, M. I., Molyneaux, L., D'Souza, M., Twigg, S. M., Wu, T., Yue, D. K., Zoungas, S., Wong, J.

“…Background Type 2 diabetes diagnosed during youth and early adulthood is aggressive and associated with a high burden of vascular complications. The increase…”
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Estimating the diagnostic accuracy of the ankle–brachial pressure index for detecting peripheral arterial disease in people with diabetes: A systematic review and meta‐analysis by Chuter, V. H., Searle, A., Barwick, A., Golledge, J., Leigh, L., Oldmeadow, C., Peterson, B., Tehan, P., Twigg, S. M.

“…Aim To systematically evaluate research investigating the accuracy of the ankle–brachial index (ABI) for diagnosing peripheral artery disease (PAD) in people…”
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Alterations in liver sinusoidal endothelium in a baboon model of type 1 diabetes by Jamieson, H. A, Cogger, V. C, Twigg, S. M, McLennan, S. V, Warren, A, Cheluvappa, R, Hilmer, S. N, Fraser, R, de Cabo, R, Le Couteur, D. G

“…Aims/hypothesis Diabetes mellitus is associated with extensive vascular pathology, yet little is known about its long-term effects on liver sinusoidal…”
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Effects of sodium butyrate on expression of members of the IGF-binding protein superfamily in human mammary epithelial cells by Tsubaki, J, Choi, WK, Ingermann, AR, Twigg, SM, Kim, HS, Rosenfeld, RG, Oh, Y

“…Dietary factors play an important role in both the development and prevention of human cancers, including breast carcinoma. One dietary micronutrient, sodium…”
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Low alanine aminotransferase levels and higher number of cardiovascular events in people with Type 2 diabetes: analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study by Williams, K. H., Sullivan, D. R., Veillard, A. S., O'Brien, R., George, J., Jenkins, A. J., Young, S., Ehnholm, C., Duffield, A., Twigg, S. M., Keech, A. C.

“…Aims To determine whether alanine aminotransferase or gamma‐glutamyltransferase levels, as markers of liver health and non‐alcoholic fatty liver disease, might…”
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Lower serum fibroblast activation protein shows promise in the exclusion of clinically significant liver fibrosis due to non-alcoholic fatty liver disease in diabetes and obesity by Williams, K.H, Viera de Ribeiro, A.J, Prakoso, E, Veillard, A.S, Shackel, N.A, Bu, Y, Brooks, B, Cavanagh, E, Raleigh, J, McLennan, S.V, McCaughan, G.W, Bachovchin, W.W, Keane, F.M, Zekry, A, Twigg, S.M, Gorrell, M.D

“…Highlights • Many patients with diabetes/obesity and NAFLD have significant liver fibrosis. • Circulating biomarkers to exclude liver fibrosis in NAFLD are…”
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