Search Results - "Twigg, Frederick F."
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Facile Discovery and Quantification of Isonitrile Natural Products via Tetrazine-Based Click Reactions
Published in Analytical chemistry (Washington) (07-01-2020)“…A facile method for the quick discovery and quantification of isonitrile compounds from microbial cultures was established based on the isonitrile–tetrazine…”
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Biosynthesis of triacsin featuring an N-hydroxytriazene pharmacophore
Published in Nature chemical biology (01-12-2021)“…Triacsins are an intriguing class of specialized metabolites possessing a conserved N -hydroxytriazene moiety not found in any other known natural products…”
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Influence of Cross-Linking on the Physical Properties and Cytotoxicity of Polyhydroxyalkanoate (PHA) Scaffolds for Tissue Engineering
Published in ACS biomaterials science & engineering (13-07-2015)“…In this study, an unsaturated copolyester, poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxy-10-undecenoate] (PHBU), was produced by an engineered strain of…”
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Identifying the Biosynthetic Gene Cluster for Triacsins with an N‐Hydroxytriazene Moiety
Published in Chembiochem : a European journal of chemical biology (02-05-2019)“…Triacsins are a family of natural products having in common an N‐hydroxytriazene moiety not found in any other known secondary metabolites. Though many studies…”
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Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Pseudomonas putida Lysine Metabolism
Published in mBio (07-05-2019)“…Despite intensive study for 50 years, the biochemical and genetic links between lysine metabolism and central metabolism in remain unresolved. To establish…”
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On the Biosynthesis of Triacsins
Published 01-01-2020“…Natural products are a source of engineering innovation and design for small molecules due to their relevance to wide swaths of the chemical sector including…”
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Dissertation -
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Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in italic toggle="yes">Pseudomonas putida /italic> Lysine Metabolism
Published in mBio (01-06-2019)“…ABSTRACT Despite intensive study for 50 years, the biochemical and genetic links between lysine metabolism and central metabolism in Pseudomonas putida remain…”
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Journal Article