Search Results - "Twickler, Th B"

Severe hypertriglyceridemia (hyperchylomicronemia), an actual challenge in daily clinic by Roeck, Yentl, Twickler, Marcel Th. B.

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A decrease in peripheral thyroid hormone conversion efficiency in patients treated with immune checkpoint inhibitors and L‐T3 as a possible alternative therapeutic escape option by Verelst, Faro R., Beyens, Michiel Marcel Jozef, Vandenbroucke, Elke, Forceville, Katheleen, (Th. B) Twickler, Marcel

“…Hypothyroidism is a frequently occurring side effect in patients under treatment with immune checkpoint inhibitors (ICIs). Actually, the origin of…”
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An intriguing focus on prolactin and the expression of a diabetic phenotype. New developments on the horizon by Twickler, Marcel Th B

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Vasculopathy in patients with Fabry disease: Current controversies and research directions by Rombach, S.M., Twickler, Th.B., Aerts, J.M.F.G., Linthorst, G.E., Wijburg, F.A., Hollak, C.E.M.

“…Fabry disease is an X-linked lysosomal storage disorder due to deficiency of the enzyme α-galactosidase A. The principal clinical manifestations of Fabry…”
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Functional consequences of prolactin signalling in endothelial cells: a potential link with angiogenesis in pathophysiology? by Reuwer, Anne Q., Nowak‐Sliwinska, Patrycja, Mans, Laurie A., van der Loos, Chris M., von der Thüsen, Jan H., Twickler, Marcel Th. B., Spek, C. Arnold, Goffin, Vincent, Griffioen, Arjan W., Borensztajn, Keren S.

“…Prolactin is best known as the polypeptide anterior pituitary hormone, which regulates the development of the mammary gland. However, it became clear over the…”
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Reducing cardiovascular disease risk in patients with type 2 diabetes and concomitant macrovascular disease: can insulin be too much of a good thing? by Rensing, K. L., Reuwer, A. Q., Arsenault, B. J., von der Thüsen, J. H., Hoekstra, J. B. L., Kastelein, J. J. P., Twickler, Th. B.

“…Despite improvement of microvascular outcomes as a consequence of optimal glucose control in patients with type 2 diabetes, prevention of macrovascular…”
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Could recombinant insulin compounds contribute to adenocarcinoma progression by stimulating local angiogenesis by Rensing, K. L, Houttuijn Bloemendaal, F. M, Weijers, E. M, Richel, D. J, Büller, H. R, Koolwijk, P, van der Loos, C. M, Twickler, Th. B, von der Thüsen, J. H

“…Aims/hypothesis Negative effects on the progression of adenocarcinomas by hyperinsulinaemia and the insulin analogue glargine (A21Gly,B31Arg,B32Arg human…”
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The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis? by Reuwer, Anne Q, van Eijk, Marco, Houttuijn-Bloemendaal, Felicia M, van der Loos, Chris M, Claessen, Nike, Teeling, Peter, Kastelein, John J P, Hamann, Jörg, Goffin, Vincent, von der Thüsen, Jan H, Twickler, Marcel Th B, Aten, Jan

“…Atherosclerotic vascular disease is the consequence of a chronic inflammatory process, and prolactin has been shown to be a component of the inflammatory…”
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Homozygous and heterozygous expression of a novel mutation of the acid-labile subunit by van Duyvenvoorde, H A, Kempers, M J E, Twickler, Th B, van Doorn, J, Gerver, W J, Noordam, C, Losekoot, M, Karperien, M, Wit, J M, Hermus, A R M M

“…ContextAcid-labile subunit (ALS) deficiency due to homozygous inactivation of the ALS gene (IGFALS) is associated with moderate short stature, and in few cases…”
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Hypercoagulable State in Cushing’s Syndrome: A Systematic Review by Van Zaane, Bregje, Nur, Erfan, Squizzato, Alessandro, Dekkers, Olaf M., Twickler, Marcel (Th) B., Fliers, Eric, Gerdes, Victor E. A., Büller, Harry R., Brandjes, Dees P. M.

“…Context: It has been debated whether an increased risk of venous thromboembolism (VTE) exists in patients with Cushing’s syndrome. Objective: We aimed to…”
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Insulin-like growth factors and pancreas beta cells by Van Haeften, T. W., Twickler, Th. B.

“…Insulin‐like growth factors (IGFs) have been implicated in normal growth, and especially foetal pancreas beta‐cell development. As low birth weight has been…”
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Endothelial insulin receptor expression in human atherosclerotic plaques: Linking micro- and macrovascular disease in diabetes? by Rensing, K.L, von der Thüsen, J.H, Weijers, E.M, Houttuijn Bloemendaal, F.M, van Lammeren, G.W, Vink, A, van der Wal, A.C, van Hinsbergh, V.W.M, van der Loos, C.M, Stroes, E.S, Koolwijk, P, Twickler, Th.B

“…Highlights ► Insulin enhances capillary-like tube formation of human microvascular endothelial cells. ► Insulin receptors are highly expressed on endothelial…”
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Prolactin does not affect human platelet aggregation or secretion by Reuwer, Anne Q, Nieuwland, Rienk, Fernandez, Isabelle, Goffin, Vincent, van Tiel, Claudia M, Schaap, Marianne C L, Berckmans, René J, Kastelein, John J P, Twickler, Marcel Th B

“…Platelets play an important role in the development of plaque formation and in the events after rupture of the atherosclerotic plaque, leading to…”
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Improvement in insulin sensitivity without concomitant changes in body composition and cardiovascular risk markers following fixed administration of a very low growth hormone (GH) dose in adults with severe GH deficiency by Yuen, Kevin C. J., Frystyk, Jan, White, Deborah K., Twickler, Th. B., Koppeschaar, Hans P. F., Harris, Philip E., Fryklund, Linda, Murgatroyd, Peter R., Dunger, David B.

“…Summary Objective  Untreated GH‐deficient adults are predisposed to insulin resistance and excess cardiovascular mortality. We showed previously that…”
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Subthalamic nucleus stimulation does not influence basal glucose metabolism or insulin sensitivity in patients with Parkinson's disease by Lammers, Nicolette M, Sondermeijer, Brigitte M, Twickler, Th B Marcel, de Bie, Rob M, Ackermans, Mariëtte T, Fliers, Eric, Schuurman, P Richard, La Fleur, Susanne E, Serlie, Mireille J

“…Animal studies have shown that central dopamine signaling influences glucose metabolism. As a first step to show this association in an experimental setting in…”
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The Cushing Reflex: Oliguria as a Reflection of an Elevated Intracranial Pressure by Twickler, Marcel Th. B., Abramowicz, D., Menovsky, T., Mortelmans, T., Leyssens, K., Van Gaal, L.

“…Oliguria is one of the clinical hallmarks of renal failure. The broad differential diagnosis is well known, but a rare cause of oliguria is intracranial…”
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Microcirculation and atherothrombotic parameters in prolactinoma patients: a pilot study by Reuwer, Anne Q., Sondermeijer, Brigitte M., Battjes, Suzanne, van Zijderveld, Rogier, Stuijver, Danka J. F., Bisschop, Peter H., Twickler, Marcel Th. B., Meijers, Joost C. M., Schlingemann, Reinier O., Stroes, Erik S.

“…Atherothrombosis is a multifactorial process, governed by an interaction between the vessel wall, hemodynamic factors and systemic atherothrombotic risk…”
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Air pollution as noxious environmental factor in the development of cardiovascular disease by MASSING, H. C, TWICKLER, Th. B, KASTELEIN, J. J. P, CRAMER, M. J. M, CASSEE, F. R

“…A strong epidemiological association has been revealed between air pollution and the occurrence of cardiovascular disease (CVD). Deleterious consequences of…”
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National differences in screening programmes for cardiovascular risks could obstruct understanding of cardiovascular prevention studies in Europe by Thio, S. L., Twickler, Th. B., Cramer, M. J., Giral, P.

“…Introduction In North-West Europe, cardiovascular disease is still a major cause of death and despite several efforts (e.g. European guidelines and…”
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Should anterior pituitary function be tested during follow-up of all patients presenting at the emergency department because of traumatic brain injury? by van der Eerden, Anke W, Twickler, Marcel Th B, Sweep, Fred C G J, Beems, Tjemme, Hendricks, Henk T, Hermus, Ad R M M, Vos, Pieter E

“…ContextA wide range (15–56%) of prevalences of anterior pituitary insufficiency are reported in patients after traumatic brain injury (TBI). However, different…”
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