Search Results - "Tweedie, J W"

Gamma-glutamyl transpeptidase inhibition suppresses milk protein synthesis in isolated ovine mammary cells by Johnston, S L, Kitson, K E, Tweedie, J W, Davis, S R, Lee, J

“…The membrane spanning enzyme gamma-glutamyl transpeptidase (gamma-GT; EC 2.3.2.2) catalyses the breakdown of the tripeptide glutathione and uses free amino…”
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Elevation of lactoferrin gene expression in developing, ductal, resting, and regressing parenchymal epithelium of the ruminant mammary gland by Molenaar, A J, Kuys, Y M, Davis, S R, Wilkins, R J, Mead, P E, Tweedie, J W

“…Accumulation of lactoferrin mRNA in mammary tissue from virgin, pregnant, lactating, and involuting ewes and cows was localized using 35S-labeled cRNA probes…”
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Studies of the N-terminal half of human lactoferrin produced from the cloned cDNA demonstrate that interlobe interactions modulate iron release by DAY, C. L, STOWELL, K. M, BAKER, E. N, TWEEDIE, J. W

“…The factors influencing iron binding and release by lactoferrin have been addressed by comparison of the native full length molecule (Lf) with the N-terminal…”
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Expression of cloned human lactoferrin in baby-hamster kidney cells by STOWELL, K. M, RADO, T. A, FUNK, W. D, TWEEDIE, J. W

“…Human lactoferrin was expressed from a cloned cDNA introduced into mammalian cells in tissue culture. Total RNA was extracted from human bone marrow, and…”
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cDNA and protein sequence of bovine lactoferrin by MEAD, P. E, TWEEDIE, J. W

“…We report the primary sequence of bovine lactoferrin determined from a combination of cDNA and protein sequencing. Bovine lactoferrin was isolated from…”
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Cloning and characterisation of the cDNA for sheep liver cytosolic aldehyde dehydrogenase by Stayner, C K, Tweedie, J W

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Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution by Day, C L, Anderson, B F, Tweedie, J W, Baker, E N

“…The three-dimensional structure of the N-terminal half-molecule of human lactoferrin, LfN, prepared by recombinant DNA methods, has been determined by X-ray…”
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Preliminary crystallographic studies of the amino terminal half of human lactoferrin in its iron-saturated and iron-free forms by Day, C L, Norris, G E, Anderson, B F, Tweedie, J W, Baker, E N

“…The amino terminal half of human lactoferrin (LfN) produced from transfected baby hamster kidney cells has been crystallized in its iron-saturated and…”
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Human class 1 aldehyde dehydrogenase. Expression and site-directed mutagenesis by Jones, K M, Kitson, T M, Kitson, K E, Hardman, M J, Tweedie, J W

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Crystal Structure and Iron-Binding Properties of the R210K Mutant of the N-Lobe of Human Lactoferrin:  Implications for Iron Release from Transferrins by Peterson, Neil A, Anderson, Bryan F, Jameson, Geoffrey B, Tweedie, John W, Baker, Edward N

“…Lactoferrin (Lf) and serum transferrin (Tf) combine high-affinity iron binding with an ability to release this iron at reduced pH. Lf, however, retains iron to…”
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Altered Domain Closure and Iron Binding in Transferrins: The Crystal Structure of the Asp60Ser Mutant of the Amino-terminal Half-molecule of Human Lactoferrin by Faber, Rick H., Bland, Tony, Day, Catherine L., Norris, Gillian E., Tweedie, John W., Baker, Edward N.

“…The crystal structure of a site-specific mutant of the N-terminal half-molecule of human lactoferrin, Lf N, in which the iron ligand Asp60 has been mutated to…”
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Three-dimensional structure of lactoferrin. Implications for function, including comparisons with transferrin by Baker, E N, Anderson, B F, Baker, H M, MacGillivray, R T, Moore, S A, Peterson, N A, Shewry, S C, Tweedie, J W

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Mutagenesis of the Histidine Ligand in Human Lactoferrin:  Iron Binding Properties and Crystal Structure of the Histidine-253 → Methionine Mutant by Nicholson, Hale, Anderson, Bryan F, Bland, Tony, Shewry, Steven C, Tweedie, John W, Baker, Edward N

“…The contribution of the conserved His ligand to iron binding in transferrins has been addressed by site-directed mutagenesis and X-ray crystallographic…”
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Mutation of Arginine 121 in Lactoferrin Destabilizes Iron Binding by Disruption of Anion Binding:  Crystal Structures of R121S and R121E Mutants by Faber, H. Rick, Baker, Christina J, Day, Catherine L, Tweedie, John W, Baker, Edward N

“…A conserved arginine residue helps to form the synergistic anion binding site in transferrins. To probe the importance of this residue for anion binding and…”
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Cloning and expression of the C-terminal lobe of human lactoferrin by Sheth, B, Stowell, K M, Day, C L, Baker, E N, Tweedie, J W

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Lactoferrin cDNA. Expression and in vitro mutagenesis by Tweedie, J W, Bain, H B, Day, C L, Nicholson, H H, Mead, P E, Sheth, B, Stowell, K M

“…The full length copy DNA (cDNA) for human lactoferrin has been synthesised by the polymerase chain reaction (PCR) using sequence specific primers. The template…”
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Adenosine triphosphate sulfurylase from Penicillium chrysogenum. II. Physical, kinetic, and regulatory properties by Tweedie, J W, Segel, I H

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Specificity of transport processes for sulfur, selenium, and molybdenum anions by filamentous fungi by Tweedie, J W, Segel, I H

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Polyadenylate-containing RNA of polyribosomes isolated from rat liver and Morris hepatoma 7800 by Tweedie, J W, Pitot, H C

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Mutagenesis of the histidine ligand in human lactoferrin: Iron binding properties and crystal structure of the histidine-253 arrow right methionine mutant by Nicholson, H, Anderson, B F, Bland, T, Shewry, S C, Tweedie, J W, Baker, EN

“…The contribution of the conserved His ligand to iron binding in transferrins has been addressed by site-directed mutagenesis and X-ray crystallographic…”
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