Search Results - "Tvrdonova, Vendula"

Role of Conserved Residues and F322 in the Extracellular Vestibule of the Rat P2X7 Receptor in Its Expression, Function and Dye Uptake Ability by Rupert, Marian, Bhattacharya, Anirban, Stillerova, Vendula Tvrdonova, Jindrichova, Marie, Mokdad, Audrey, Boué-Grabot, Eric, Zemkova, Hana

“…Activation of the P2X7 receptor results in the opening of a large pore that plays a role in immune responses, apoptosis, and many other physiological and…”
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Identification of functionally important residues of the rat P2X4 receptor by alanine scanning mutagenesis of the dorsal fin and left flipper domains by Tvrdonova, Vendula, Rokic, Milos B, Stojilkovic, Stanko S, Zemkova, Hana

“…Crystallization of the zebrafish P2X4 receptor in both open and closed states revealed conformational differences in the ectodomain structures, including the…”
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Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor by Rokic, Milos B, Stojilkovic, Stanko S, Vavra, Vojtech, Kuzyk, Pavlo, Tvrdonova, Vendula, Zemkova, Hana

“…The binding of ATP to trimeric P2X receptors (P2XR) causes an enlargement of the receptor extracellular vestibule, leading to opening of the cation-selective…”
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Allosteric regulation of the P2X4 receptor channel pore dilation by Zemkova, Hana, Khadra, Anmar, Rokic, Milos B., Tvrdonova, Vendula, Sherman, Arthur, Stojilkovic, Stanko S.

“…Allosteric modulators of ligand-gated receptor channels induce conformational changes of the entire protein that alter potencies and efficacies for orthosteric…”
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Role of the Ectodomain Serine 275 in Shaping the Binding Pocket of the ATP-Gated P2X3 Receptor by Petrenko, Nataliia, Khafizov, Kamil, Tvrdonova, Vendula, Skorinkin, Andrei, Giniatullin, Rashid

“…ATP-activated P2X3 receptors expressed in nociceptive sensory neurons play an important role in pain signaling. Basic properties of this receptor subtype,…”
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Roles of conserved ectodomain cysteines of the rat P2X4 purinoreceptor in agonist binding and channel gating by Rokic, M B, Tvrdoňová, V, Vávra, V, Jindřichová, M, Obšil, T, Stojilkovic, S S, Zemková, H

“…Mammalian P2X receptors contain 10 conserved cysteine residues in their ectodomains, which form five disulfide bonds (SS1-5). Here, we analyzed the relevance…”
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