Search Results - "Tuytten, Robin"

A machine learning algorithm to differentiate bipolar disorder from major depressive disorder using an online mental health questionnaire and blood biomarker data by Tomasik, Jakub, Han, Sung Yeon Sarah, Barton-Owen, Giles, Mirea, Dan-Mircea, Martin-Key, Nayra A., Rustogi, Nitin, Lago, Santiago G., Olmert, Tony, Cooper, Jason D., Ozcan, Sureyya, Eljasz, Pawel, Thomas, Grégoire, Tuytten, Robin, Metcalfe, Tim, Schei, Thea S., Farrag, Lynn P., Friend, Lauren V., Bell, Emily, Cowell, Dan, Bahn, Sabine

“…The vast personal and economic burden of mood disorders is largely caused by their under- and misdiagnosis, which is associated with ineffective treatment and…”
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Early cost-effectiveness analysis of screening for preeclampsia in nulliparous women: A modelling approach in European high-income settings by Zakiyah, Neily, Tuytten, Robin, Baker, Philip N, Kenny, Louise C, Postma, Maarten J, van Asselt, Antoinette D I

“…Preeclampsia causes substantial maternal and perinatal morbidity and mortality and significant societal economic impact. Effective screening would facilitate…”
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Prediction of preeclampsia risk in first time pregnant women: Metabolite biomarkers for a clinical test by Kenny, Louise C, Thomas, Grégoire, Poston, Lucilla, Myers, Jenny E, Simpson, Nigel A B, McCarthy, Fergus P, Brown, Leslie W, Bond, Alison E, Tuytten, Robin, Baker, Philip N

“…Preeclampsia remains a leading cause of maternal and perinatal morbidity and mortality. Accurate prediction of preeclampsia risk would enable more effective,…”
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Highly efficient peptide separations in proteomics Part 2: Bi-and multidimensional liquid-based separation techniques by SANDRA, Koen, MOSHIR, Mahan, D'HONDT, Filip, TUYTTEN, Robin, VERLEYSEN, Katleen, KAS, Koen, FRANCOIS, Isabelle, SANDRA, Pat

“…Multidimensional liquid-based separation techniques are described for maximizing the resolution of the enormous number of peptides generated upon tryptic…”
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Unbiased plasma proteomics for novel diagnostic biomarkers in cardiovascular disease: identification of quiescin Q6 as a candidate biomarker of acutely decompensated heart failure by Mebazaa, Alexandre, Vanpoucke, Griet, Thomas, Gregoire, Verleysen, Katleen, Cohen-Solal, Alain, Vanderheyden, Marc, Bartunek, Jozef, Mueller, Christian, Launay, Jean-Marie, Van Landuyt, Natalie, D'Hondt, Filip, Verschuere, Elisabeth, Vanhaute, Caroline, Tuytten, Robin, Vanneste, Lies, De Cremer, Koen, Wuyts, Jan, Davies, Huw, Moerman, Piet, Logeart, Damien, Collet, Corinne, Lortat-Jacob, Brice, Tavares, Miguel, Laroy, Wouter, Januzzi, James L, Samuel, Jane-Lise, Kas, Koen

“…Biochemical marker testing has improved the evaluation and management of patients with cardiovascular diseases over the past decade. Natriuretic peptides…”
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Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort by Maher, Gillian M, Kenny, Louise C, Navaratnam, Kate, Alfirevic, Zarko, Sheehan, Darina, Baker, Philip N, Gluud, Christian, Tuytten, Robin, Kublickas, Marius, Niklasson, Boel, Duvekot, Johannes J, van den Berg, Caroline B, Wu, Pensee, Kublickiene, Karolina, McCarthy, Fergus P, Khashan, Ali S

“…Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to enable the…”
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Toward Clinical Proteomics on a Next-Generation Sequencing Platform by Turner, Daniel J, Tuytten, Robin, Janssen, Kris P.F, Lammertyn, Jeroen, Wuyts, Jan, Pollet, Jeroen, Eyckerman, Sven, Brown, Clive, Kas, Koen

“…We report the first next generation sequencing (NGS) application to identify and quantify proteins. Customization of protein specific aptamers enabled direct…”
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A novel method for interrogating receiver operating characteristic curves for assessing prognostic tests by Thomas, Grégoire, Kenny, Louise C, Baker, Philip N, Tuytten, Robin

“…Disease prevalence is rarely explicitly considered in the early stages of the development of novel prognostic tests. Rather, researchers use the area under the…”
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Role of Nitrogen Lewis Basicity in Boronate Affinity Chromatography of Nucleosides by Tuytten, Robin, Lemière, Filip, Esmans, Eddy L, Herrebout, Wouter A, van der Veken, Benjamin J, Maes, Bert U. W, Witters, Erwin, Newton, Russell P, Dudley, Ed

“…Urinary modified nucleosides have a potential role as cancer biomarkers, and most of the methods used in their study have utilized low-pressure phenylboronate…”
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Analysis of urinary nucleosides. IV. Identification of urinary purine nucleosides by liquid chromatography/electrospray mass spectrometry by Dudley, Edward, Lemière, Filip, Van Dongen, Walter, Tuytten, Robin, El-Sharkawi, Salah, Brenton, A. Gareth, Esmans, Eddy L., Newton, Russell P.

“…Modified urinary nucleosides are potentially invaluable in cancer diagnosis. High‐performance liquid chromatography (HPLC) was combined with full scan mass…”
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A step closer to using metabolite biomarkers to improve early pregnancy prediction of preeclampsia by Tuytten, Robin, Syngelaki, Argyro, Thomas, Grégoire, Nicolaides, Kypros H.

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Investigation of the use of immobilised metal affinity chromatography for the on-line sample clean up and pre-concentration of nucleotides prior to their determination by ion pair liquid chromatography-electrospray mass spectrometry: a pilot study by Tuytten, Robin, Lemière, Filip, Van Dongen, Walter, Slegers, Herman, Newton, Russell P, Esmans, Eddy L

“…This study explored an alternative way to enrich and pre-purify biological samples containing nucleoside mono-, di- and triphosphates. These compounds were…”
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Revealing of endogenous Marinobufagin by an ultra-specific and sensitive UHPLC-MS/MS assay in pregnant women by Lenaerts, Charline, Bond, Liz, Tuytten, Robin, Blankert, Bertrand

“…Marinobufagenin (MBG) is a bufadienolide cardiac inotrope implicated in volume expansion-mediated hypertensive states including essential hypertension and…”
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First-trimester preterm preeclampsia prediction with metabolite biomarkers: differential prediction according to maternal body mass index by Tuytten, Robin, Syngelaki, Argyro, Thomas, Grégoire, Panigassi, Ana, Brown, Leslie W., Ortea, Paloma, Nicolaides, Kypros H.

“…Prediction of preeclampsia risk is key to informing effective maternal care. Current screening for preeclampsia at 11 to 13 weeks of gestation using maternal…”
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Relationship between the concentration of ergothioneine in plasma and the likelihood of developing pre-eclampsia by Kenny, Louise C, Brown, Leslie W, Ortea, Paloma, Tuytten, Robin, Kell, Douglas B

“…Ergothioneine, an antioxidant nutraceutical mainly at present derived from the dietary intake of mushrooms, has been suggested as a preventive for…”
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Diagnostic prediction model development using data from dried blood spot proteomics and a digital mental health assessment to identify major depressive disorder among individuals presenting with low mood by Han, Sung Yeon Sarah, Tomasik, Jakub, Rustogi, Nitin, Lago, Santiago G., Barton-Owen, Giles, Eljasz, Pawel, Cooper, Jason D., Ozcan, Sureyya, Olmert, Tony, Farrag, Lynn P., Friend, Lauren V., Bell, Emily, Cowell, Dan, Thomas, Grégoire, Tuytten, Robin, Bahn, Sabine

“…•Diagnostic prediction models of depression were developed.•Models showed good discrimination between depressed patients and low mood controls.•Models could…”
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Preterm preeclampsia screening using biomarkers: combining phenotypic classifiers into robust prediction models by Thomas, Grégoire, Syngelaki, Argyro, Hamed, Karam, Perez-Montaño, Anais, Panigassi, Ana, Tuytten, Robin, Nicolaides, Kypros H.

“…BACKGROUNDPreeclampsia screening is a critical component of antenatal care worldwide. Currently, the most developed screening test for preeclampsia at 11 to 13…”
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Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort [version 3; peer review: 2 approved] by Kate Navaratnam, Louise C. Kenny, Darina Sheehan, Zarko Alfirevic, Christian Gluud, Philip N. Baker, Marius Kublickas, Robin Tuytten, Johannes J. Duvekot, Boel Niklasson, Pensee Wu, Caroline B. van den Berg, Ali S. Khashan, Karolina Kublickiene, Gillian M. Maher, Fergus P. McCarthy

“…Background Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to…”
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Integrated Proteomics Pipeline Yields Novel Biomarkers for Predicting Preeclampsia by Myers, Jenny E, Tuytten, Robin, Thomas, Grégoire, Laroy, Wouter, Kas, Koen, Vanpoucke, Griet, Roberts, Claire T, Kenny, Louise C, Simpson, Nigel A.B, Baker, Philip N, North, Robyn A

“…Preeclampsia, a hypertensive pregnancy complication, is largely unpredictable in healthy nulliparous pregnant women. Accurate preeclampsia prediction in this…”
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Development of an On-Line SPE-LC–ESI-MS Method for Urinary Nucleosides:  Hyphenation of Aprotic Boronic Acid Chromatography with Hydrophilic Interaction LC–ESI-MS by Tuytten, Robin, Lemière, Filip, Van Dongen, Walter, Witters, Erwin, Esmans, Eddy L, Newton, Russell P, Dudley, Ed

“…The development of an on-line automated SPE-HPLC– ESI-MS method is described for targeted metabolomic analysis of urinary modified nucleoside levels. The setup…”
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