Search Results - "Tuveri, Stefania"
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Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology
Published in Nature communications (12-03-2024)“…Circulating cell-free DNA (cfDNA) fragments have characteristics that are specific to the cell types that release them. Current methods for cfDNA deconvolution…”
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MetDecode: methylation-based deconvolution of cell-free DNA for noninvasive multi-cancer typing
Published in Bioinformatics (Oxford, England) (02-09-2024)“…Abstract Motivation Circulating-cell free DNA (cfDNA) is widely explored as a noninvasive biomarker for cancer screening and diagnosis. The ability to decode…”
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Primary mediastinal large B‐cell lymphoma is characterized by large‐scale copy‐neutral loss of heterozygosity
Published in Genes chromosomes & cancer (01-10-2022)“…Development of primary mediastinal B‐cell lymphoma (PMBL) is driven by cumulative genomic aberrations. We discovered a unique copy‐neutral loss of…”
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Detection of incipient tumours by screening of circulating plasma DNA: hype or hope?
Published in Acta clinica belgica (English ed. Online) (02-01-2020)“…Background: The last half-decade has been marked by a rapid expansion of research efforts in the field of so-called liquid biopsies, thereby investigating the…”
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