Search Results - "Tutt, A.L."

Validation of an ELISA for the determination of rituximab pharmacokinetics in clinical trials subjects by Hampson, G., Ward, T.H., Cummings, J., Bayne, M., Tutt, A.L., Cragg, M.S., Dive, C., Illidge, T.M.

“…Rituximab is a chimeric anti-CD20 monoclonal antibody that has revolutionised the treatment of many B-cell malignancies, and is now increasingly being used in…”
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Development, validation and application of ELISAs for pharmacokinetic and HACA assessment of a chimeric anti-CD40 monoclonal antibody in human serum by Chowdhury, F., Tutt, A.L., Chan, C., Glennie, M., Johnson, P.W.

“…As part of a Phase I chimeric anti-CD40 monoclonal antibody clinical trial, two enzyme-linked immunosorbent assays (ELISAs) were developed for secondary…”
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Treatment of B-cell lymphomas with combination of bispecific antibodies and saporin by French, R R, Hamblin, T J, Bell, A J, Tutt, A L, Glennie, M J

“…We report the use of a bispecific F(ab')2 antibody to target the ribosome-inactivating protein saporin to the surface antigen CD22 in the treatment of…”
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Response of B-cell lymphoma to a combination of bispecific antibodies and saporin by French, Ruth R., Bell, A.J., Hamblin, T.J., Tutt, A.L., Glennie, M.J.

“…Observations are described using a combination of two bispecific F(ab′) 2 antibodies (BsAb) to deliver the ribosome-inactivating protein, saporin, in the…”
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Characterization of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab')2 derivative for recruitment of cytotoxic effectors by Greenman, J, Tutt, A L, George, A J, Pulford, K A, Stevenson, G T, Glennie, M J

“…Fc gamma RII (CDw32) on monocytes is capable of triggering both phagocytosis and lysis of chick red blood cells (CRBC) coated with antibody of the appropriate…”
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Monoclonal Anti-Light Chain Idiotype as a Tumor-Specific Probe for Human Neoplastic B Lymphocytes by Wrightham, M., Tutt, A.L., Glennie, M.J., Hamblin, T.J., Stevenson, G.T., Stevenson, F.K.

“…Tumor cells from patients with B cell neoplasms often secrete small amounts of free monoclonal light chains that can be found in the urine. Such tumor-derived…”
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